INSULIN & MTOR
February 8, 2021POLYAMINES & THEIR EFFECT ON BRAIN (NMDA, DEPRESSION, SUICIDE RISK)
February 9, 2021Excitotoxicity is a process where nerve cells are damaged and killed by excessive stimulation from neurotransmitters, particularly glutamate, leading to an influx of calcium ions into the cells. This triggers a cascade of events that ultimately result in cell death.
Excitotoxicity is harmful to the brain due to various reasons:
– Neuronal damage and death, contributing to neurodegenerative diseases like Alzheimer’s Disease and epilepsy.
– Oxidative stress, disrupting cellular processes and leading to cell death.
– Mitochondrial dysfunction, impairing energy metabolism and producing free radicals.
– Calcium dysregulation, leading to mitochondrial and synaptic dysfunction.
– Astrocytic dysfunction, disrupting glutamate homeostasis and increasing neuronal excitability.
– Inflammatory responses, exacerbating neuronal damage.
– Disruption of normal cellular processes, mitochondrial dysfunction, oxidative stress, and ultimately cell death.
– Contribution to neurodegenerative diseases like ALS.
– Involvement in various neurological disorders such as Parkinson’s disease, stroke, and ALS.
– Disruption of neurotransmitter and ion balance mechanisms.
– Impaired synaptic function and cognitive processes.
The role of glutamate excitotoxicity and neuroinflammation in depression and suicidal behavior are as follows:
1. **Glutamate Excitotoxicity**: – Abnormalities in glutamatergic neurotransmission are common in depressed individuals. – Overactivation of N-methyl-D-aspartate receptors (NMDAR) plays a critical role in major depressive disorder (MDD). – NMDA antagonists have been investigated for their potential antidepressant effects and improvement of suicidal ideation beyond the traditional monoamine hypothesis. – Elevated levels of kynurenic acid, a metabolite of the kynurenine pathway, can reduce glutamate release in certain brain regions and inhibit specific receptors. – Increased levels of kynurenic acid may lead to altered connectivity between cortical structures and the limbic system.
2. **Neuroinflammation**: – Inflammatory processes in depressed patients suggest the immunological origin of major depression. – Inflammatory mediators and oxidative stress can lead to glutamate excitotoxicity, playing a significant role in the pathogenesis of MDD. – Microglial cells, as immunologic sentinel cells of the brain, are associated with abnormal immune responses in MDD and suicidal behavior. – Microglial cells are proposed as potential targets for both glutamatergic- and inflammatory-mediated alterations underlying MDD and suicidal behavior. – Aberrant levels of quinolinic acid, produced by abnormal pathways inside microglia cells, are considered intracellular mediators of pathologically inflammatory- and glutamatergic-related changes.
Therefore, glutamate excitotoxicity and neuroinflammation play crucial roles in the development and progression of depression and suicidal behavior, with a specific focus on the involvement of microglial cells in these processes.
- Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 are involved in both excitotoxin-induced neurodegeneration and regeneration
- excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator
- Inflammatory cytokines IL-1α, IL-1β, IL-6, and TNF-α impart neuroprotection to an excitotoxin through distinct pathways
- Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure
- … dissociations of the effects of amygdala and insular cortex lesions on conditioned taste aversion, passive avoidance, and neophobia in the rat using the excitotoxin …
- L-cysteine, a bicarbonate-sensitive endogenous excitotoxin
- excitotoxin lesions in primates as a model for Huntington’s disease: histopathologic and neurochemical characterization
- A possible central mechanism in autism spectrum disorders, part 3: the role of excitotoxin food additives and the synergistic effects of other environmental toxins.
- The excitotoxin quinolinic acid induces tau phosphorylation in human neurons
- Nerve growth factor (NGF) regulates adult rat cultured dorsal root ganglion neuron responses to the excitotoxin capsaicin
- Activated human microglia produce the excitotoxin quinolinic acid
- The excitotoxin hypothesis in relation to cerebral ischemia.
- Cyclin-dependent kinase 4 and cyclin D1 are required for excitotoxin-induced neuronal cell death in vivo
- … , a cAMP-Specific Phosphodiesterase-4 Inhibitor, Reduces Oxidative Stress and Improves Synapse Functions in Human Cortical Neurons Exposed to the excitotoxin …
- excitotoxin lesions suggest an aspartatergic projection from rat medial prefrontal cortex to ventral tegmental area
- Glutamate‐mediated injury in focal cerebral ischemia: the excitotoxin hypothesis revised
- Glucocorticoids worsen excitotoxin-induced expression of pro-inflammatory cytokines in hippocampal cultures
- Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons
- Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina
- Nuclear factor-κB contributes to excitotoxin-induced apoptosis in rat striatum
- Differential sparing of somatostatin‐neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions
- Extensive neuroprotection by choroid plexus transplants in excitotoxin lesioned monkeys
- Cellular mechanism of action of resiniferatoxin: a potent sensory neuron excitotoxin
- Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans
- Enhanced cellular glutathione peroxidase immunoreactivity in activated astrocytes and in microglia during excitotoxin induced neurodegeneration
- Tissue-type plasminogen activator protects neurons from excitotoxin-induced cell death via activation of the ERK 1/2–CREB–ATF3 signaling pathway
- Resistance to excitotoxin-induced seizures and neuronal death in mice lacking the preprotachykinin A gene
- Motor neuron degeneration induced by excitotoxin agonists has features in common with those seen in the SOD-1 transgenic mouse model of amyotrophic lateral …
- A caspase‐3‐dependent pathway is predominantly activated by the excitotoxin pregnenolone sulfate and requires early and late cytochrome c release and cell …
- Chronic excitotoxin-induced axon degeneration in a compartmented neuronal culture model
- Short-and long-term consequences of intracranial injections of the excitotoxin, quinolinic acid, as evidenced by GFA immunohistochemistry of astrocytes
- Contribution of ventral tegmental area dopamine neurons to expression of conditional fear: effects of electrical stimulation, excitotoxin lesions, and quinpirole infusion …
- Glial cell line-derived neurotrophic factor attenuates the excitotoxin-induced behavioral and neurochemical deficits in a rodent model of Huntington’s disease
- Induction of β-amyloid-containing polypeptides in hippocampus: evidence for a concomitant loss of synaptic proteins and interactions with an excitotoxin
- Evidence for activation of caspase‐3‐like protease in excitotoxin‐and hypoxia/hypoglycemia‐injured neurons
- Gonadal hormones affect neuronal vulnerability to excitotoxin-induced degeneration
- Neurochemical characterization of excitotoxin lesions in the cerebral cortex
- The excitotoxin quinolinic acid is present in the brain of several mammals and its cortical content increases during the aging process
- Proteomic identification of hippocampal proteins vulnerable to oxidative stress in excitotoxin-induced acute neuronal injury
- The HDAC6 inhibitor trichostatin A acetylates microtubules and protects axons from excitotoxin-induced degeneration in a compartmented culture model
- Aminooxyacetic acid results in excitotoxin lesions by a novel indirect mechanism
- PARP cleavage, DNA fragmentation, and pyknosis during excitotoxin-induced neuronal death
- The excitotoxin quinolinic acid is present and unevenly distributed in the rat brain
- excitotoxin-mediated neuron death in youth and old age
- excitotoxin paraventricular nucleus lesions: stress and endocrine reactivity and oxytocin mRNA levels
- Quercetin attenuates oxygen–glucose deprivation-and excitotoxin-induced neurotoxicity in primary cortical cell cultures
- Rod bipolar cells dysfunction occurs before ganglion cells loss in excitotoxin-damaged mouse retina
- excitotoxin-induced caspase-3 activation and microtubule disintegration in axons is inhibited by taxol
- What excitotoxin kills striatal neurons in Huntington’s disease? Clues from neurochemical studies
- Glucocorticoid protection of oligodendrocytes against excitotoxin involving hypoxia-inducible factor-1α in a cell-type-specific manner
- Overexpression of neurotrophin receptor p75 contributes to the excitotoxin-induced cholinergic neuronal death in rat basal forebrain
- Nerve growth factor selectively prevents excitotoxin induced degeneration of striatal cholinergic neurones
- Sources of reactive oxygen species production in excitotoxin-stimulated cerebellar granule cells
- Age-related changes in tolerance to the marine algal excitotoxin domoic acid
- Ubiquinone protects cultured neurons against spontaneous and excitotoxin-induced degeneration
- The Lathyrus excitotoxin β-N-oxalyl-l-α, β-diaminopropionic acid is a substrate of the l-cystine/l-glutamate exchanger system xc−
- Induction of tumor suppressor p53 and DNA fragmentation in organotypic hippocampal cultures following excitotoxin treatment
- Brain and retinal damage from lathyrus excitotoxin, β-N-oxalyl-L-α, β-diaminopropionic acid
- Movement disorder following excitotoxin lesions in primates.
- Neuronal and nonneuronal COX‐2 expression confers neurotoxic and neuroprotective phenotypes in response to excitotoxin challenge
- Cyclophilin-A is involved in excitotoxin-induced caspase activation in rat neuronal B50 cells
- Moderately delayed post-insult treatment with normobaric hyperoxia reduces excitotoxin-induced neuronal degeneration but increases ischemia-induced …
- Behavioral disinhibition following basal forebrain excitotoxin lesions: alcohol consumption, defensive aggression, impulsivity and serotonin levels
- Iron‐mediated oxidation of 3, 4‐dihydroxyphenylalanine to an excitotoxin
- Potential mechanism of cellular uptake of the excitotoxin quinolinic acid in primary human neurons
- Strain differences in convulsive response to the excitotoxin kainic acid.
- Safranal attenuates excitotoxin-induced oxidative OLN-93 cells injury
- Increased levels of the excitotoxin quinolinic acid in spinal cord following contusion injury
- Hypoxia-ischemia or excitotoxin-induced tissue plasminogen activator-dependent gelatinase activation in mice neonate brain microvessels
- Calcium influx accompanies but does not cause excitotoxin-induced neuronal necrosis in retina
- Hippocalcin protects hippocampal neurons against excitotoxin damage by enhancing calcium extrusion
- Pregnenolone sulfate, a naturally occurring excitotoxin involved in delayed retinal cell death
- The effects of excitotoxin lesions of the lateral hypothalamus on self-stimulation reward
- Co-stimulation of cyclic-AMP-linked metabotropic glutamate receptors in rat striatum attenuates excitotoxin-induced nuclear factor-κB activation and apoptosis
- excitotoxin lesions do not mimic the alteration of somatostatin in Huntington’s disease
- Protection by MK-801 against hypoxia-, excitotoxin-, and depolarization-induced neuronal damage in vitro
- excitotoxin lesions of the zona incerta/lateral tegmentum continuum: effects on male sexual behavior in rats
- 3-Nitropropionic acid is an indirect excitotoxin to cultured cerebellar granule neurons
- Variation in Galr1 expression determines susceptibility to excitotoxin‐induced cell death in mice
- excitotoxin‐Induced Neuronal Death Is Associated with Response of a Unique Intracellular Aspartic Proteinase, Cathepsin E
- Differences in ionotropic glutamate receptor subunit expression are not responsible for strain-dependent susceptibility to excitotoxin-induced injury
- Induction of Ornithine Decarboxylase in Cerebral Cortex by excitotoxin Lesion of Nucleus Basalis: Association with Postsynaptic Responsiveness and N‐Methyl‐d …
- The direction of apomorphine-induced rotation behavior is dependent on the location of excitotoxin in the rat basal ganglia
- Comparison of in vivo binding properties of the 18-kDa translocator protein (TSPO) ligands [18 F] PBR102 and [18 F] PBR111 in a model of excitotoxin-induced …
- Microtubule‐dependent processes precede pathological calcium influx in excitotoxin‐induced axon degeneration
- Lathyrus excitotoxin: mechanism of neuronal excitation by L-2-oxalylamino-3-amino-and L-3-oxalylamino-2-amino-propionic acid
- … of glia‐derived nexin/protease nexin 1 depends on mode of lesion‐induction or terminal degeneration: Observations after excitotoxin or 6‐hydroxydopamine lesions …
- GM1 ganglioside protects nucleus basalis from excitotoxin damage: reduced cortical cholinergic losses and animal mortality
- Effects of excitotoxin exposure on metabolic rate of primary hippocampal cultures: application of silicon microphysiometry to neurobiology
- Patterns of excitotoxin-induced brain lesions in the newborn rabbit: a neuropathological and MRI correlation
- Alterations in behavioral responses to stressors following excitotoxin lesions of dorsomedial hypothalamic regions
- Long-term sensitization of apomorphine-induced rotation behavior in rats with dopamine deafferentation or excitotoxin lesions of the striatum
- NO-flurbiprofen attenuates excitotoxin-induced brain inflammation, and releases nitric oxide in the brain
- Effect of excitotoxin lesions in the medial prefrontal cortex on cortical and subcortical catecholamine turnover in the rat
- Magnetic resonance imaging to monitor pathology of caudate-putamen after excitotoxin-induced neuronal loss in the nonhuman primate brain
- excitotoxin-induced myocardial necrosis
- TOPA quinone, a kainate-like agonist and excitotoxin is generated by a catecholaminergic cell line
- Effects of antenatal uteroplacental hypoperfusion on neonatal microvascularisation and excitotoxin sensitivity in mice
- Alterations in Extracellular Amino Acids and Ca2+ Following excitotoxin Administration and During Status Epilepticus
- Induction of c-fos mRNA in cerebral cortex by excitotoxin stimulation of cortical inputs: involvement ofN-methyl-d-aspartate receptors
- Distribution of neuropeptide Y immunoreactivity in the rat basal ganglia: effects of excitotoxin lesions to caudate-putamen
- Fetal striatal tissue grafts into excitotoxin-lesioned striatum: pharmacological and behavioral aspects
- In vitro culture duration does not impact the ability of encapsulated choroid plexus transplants to prevent neurological deficits in an excitotoxin-lesioned rat model of …
- excitotoxin-induced lesions of the central but not basolateral nucleus of the amygdala modulate the baroreceptor heart rate reflex in conscious rats
- Recombinant human ciliary neurotrophic factor alters the threshold of hippocampal pyramidal neuron sensitivity to excitotoxin damage: synergistic effects of …
- T1 and T2 weighted magnetic resonance imaging of excitotoxin lesions and neural transplants in rat brain in vivo
- L-trans-2, 3-pyrrolidine dicarboxylate: characterization of a novel excitotoxin
- 6-Hydroxydopamine and excitotoxin lesions of medial prefrontal cortex fail to affect schedule-induced drinking in the rat
- Is quinolinic acid an endogenous excitotoxin in alcohol withdrawal?
- The calcium response to the excitotoxin kainate is amplified by subsequent reduction of extracellular sodium
- Quantitative morphometric analysis of the neurotoxic effects of the excitotoxin, ibotenic acid, on the basal forebrain.
- Receptor interactions of β-N-oxalyl-L-α, β-diaminopropionic acid, the Lathyrus sativus putative excitotoxin, with synaptic membranes
- The NMDA receptor agonist DL-(tetrazol-5-yl) glycine is a highly potent excitotoxin
- Crude and Partition Extracts of Newbouldia laevis Leaves Attenuate excitotoxin-induced Stereotypy in Mice
- Effect of fetal striatal and astrocyte transplants into unilateral excitotoxin-lesioned striatum
- Low dose quetiapine reverses deficits in contextual and cued fear conditioning in rats with excitotoxin-induced hippocampal neuropathy
- excitotoxin-induced cerebral hyperemia in newborn piglets: regional cerebral blood flow mapping with contrast-enhanced power Doppler US.
- Effects of nigral dopaminergic lesions and striatal excitotoxin lesions on brain converting enzyme
- excitotoxin-induced degeneration of rat vagal afferent neurons
- Differential temporal patterns of expression of immediate early genes in cerebral cortex induced by intracerebral excitotoxin injection: sensitivity to dexamethasone …
- Ultrastructural and immunocytochemical studies of macrophages in an excitotoxin induced lesion in the rat brain.
- … and anatomical analysis of cholinergic, noradrenergic and serotonergic innervation of fetal neocortical transplants placed in excitotoxin-induced neocortical lesions of …
- excitotoxin-induced changes in transglutaminase during differentiation of cerebellar granule cells
- Synthesis and pharmacology of N-alkylated derivatives of the excitotoxin ibotenic acid
- Local and remote microvascular changes in excitotoxin-induced focal brain lesions
- 6-Hydroxydopa, a catecholamine neurotoxin and endogenous excitotoxin at non-NMDA receptors
- ATP as a marker of excitotoxin-induced nerve cell death in vivo
- Immuno-electron microscopy reveals that the excitotoxin quinolinate is associated with the plasma membrane in human peripheral blood monocytes/macrophages
- Central administration of the excitotoxin N-methyl-D-aspartate increases nerve growth factor mRNA in vivo.
- Role of Group III Metabotropic Glutamate Receptors in excitotoxin‐Induced Cerebellar Granule Cell Death
- Expression of c-fos mRNA and c-fos protein in neocortical transplants placed into excitotoxin-induced lesions in adult rats
- excitotoxin lesion of nucleus basalis causes a specific decrease in Go mRNA in cerebral cortex: sensitivity to MK-801
- excitotoxin induction of ornithine decarboxylase in cerebral cortex is reduced by phospholipase A2 inhibition
- excitotoxin mediated neuronal loss and the regulation of excitatory amino acid release in the aging brain
- Depletion of cortical cholecystokinin levels after excitotoxin injection into the nucleus basalis: sensitivity to MK-801
- Neuronal damage in the albino rat: excitotoxin, microtubule inhibitor synergism
- Differential effects of dexamethasone on the induction of c-fos, zif-268 and ornithine decarboxylase by excitotoxin
- Neuroprotective Effects of a Variety of Pomegranate Juice Extracts (PJE) Against the excitotoxin Quinolinic Acid in Human Primary Neurons.
- excitotoxin-lesioned rat striatum
- Macrophage-microglia responses to excitotoxin-induced degeneration in the central nervous system
- Effect of selective excitatory amino acid antagonists on excitotoxin-induced changes in APP mRNA expression
- Mechanisms of Zn2+-and excitotoxin-induced oligodendrocyte progenitor cell injury.
- The role of metabotropic receptors in excitotoxin-induced rat cerebellar granule cell death
- Evidence for the endogenous formation of the excitotoxin TOPA quinone.
- 47. Noradrenaline re-uptake inhibition influences neuroinflammatory and degenerative changes associated with the excitotoxin kainic acid
- MECHANISMS OF KAINIC ACID INDUCED HIPPOCAMPAL EPILEPSY (GLUTAMIC ACID DECARBOXYLASE, excitotoxin, NEUROTOXICOLOGY).
- The excitotoxin Elimination Diet: A Novel Dietary Intervention for those with Fibromyalgia and Irritable Bowel Syndrome
- Upregulation of hippocampal Senescence marker protein 30 in response to excitotoxin is involved in the ERK-mediated activation of astrocytes
- MSG (Monosodium Glutamate): The Flavor Enhancing excitotoxin Linked to Obesity, Brain Damage and other Diseases
- Pretreatment of curcumin protects hippocampal neurons against excitotoxin-induced cell death
- Variation in Galr1 expression determines the susceptibility to excitotoxin-induced neuronal death in mice
- EVALUATION OF excitotoxin RECEPTORS
- excitotoxic and excitoprotective mechanisms
- excitotoxic cell death
- Alternative excitotoxic hypotheses
- II. excitotoxic models for neurodegenerative disorders
- Calcium and excitotoxic neuronal injury
- Inciting excitotoxic cytocide among central neurons
- excitotoxic mechanisms of epileptic brain damage.
- Progression of ischaemic stroke and excitotoxic aminoacids
- excitotoxic amino acids and neuropsychiatric disorders.
- Requirement for superoxide in excitotoxic cell death
- Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches
- excitotoxic injury of the neostriatum: a model for Huntington’s disease
- NBQX attenuates excitotoxic injury in developing white matter
- Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?
- Glutamate receptors and the induction of excitotoxic neuronal death
- Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death
- Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions
- A revised excitotoxic hypothesis of schizophrenia: therapeutic implications
- β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage
- Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models
- excitotoxic spinal cord injury: behavioral and morphological characteristics of a central pain model
- Glioma cells release excitotoxic concentrations of glutamate
- Zinc and excitotoxic brain injury: a new model
- The link between excitotoxic oligodendroglial death and demyelinating diseases
- Molecular mechanisms underlying specificity of excitotoxic signaling in neurons
- Buckminsterfullerenol free radical scavengers reduce excitotoxic and apoptotic death of cultured cortical neurons
- Diffusion-weighted imaging of acute excitotoxic brain injury
- Calcium, free radicals, and excitotoxic neuronal death in primary cell culture
- Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage
- Conditioned taste aversion in rats with excitotoxic brain lesions
- excitotoxic neuronal death in the immature brain is an apoptosis‐necrosis morphological continuum
- Mutant huntingtin enhances excitotoxic cell death
- excitotoxic neurodegeneration in Alzheimer disease: new hypothesis and new therapeutic strategies
- Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis
- excitotoxic mechanisms in the pathogenesis of amyotrophic lateral sclerosis.
- Models of white matter injury: comparison of infectious, hypoxic‐ischemic, and excitotoxic insults
- excitotoxic mechanisms and the role of astrocytic glutamate transporters in traumatic brain injury
- Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults
- Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors
- Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration?
- Distinguishing excitotoxic from apoptotic neurodegeneration in the developing rat brain
- Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid
- Postpubertal emergence of hyperresponsiveness to stress and to amphetamine after neonatal excitotoxic hippocampal damage: a potential animal model of …
- Object recognition and location memory in monkeys with excitotoxic lesions of the amygdala and hippocampus
- The basal forebrain-cortical cholinergic system: interpreting the functional consequences of excitotoxic lesions
- Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
- Protection and reversal of excitotoxic neuronal damage by glucagon-like peptide-1 and exendin-4
- Manganese injection into the rat striatum produces excitotoxic lesions by impairing energy metabolism
- Akt1 regulates a JNK scaffold during excitotoxic apoptosis
- Ethambutol is toxic to retinal ganglion cells via an excitotoxic pathway.
- excitotoxic index—a biochemical marker of selective vulnerability
- Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor
- Early microglial activation following neonatal excitotoxic brain damage in mice: a potential target for neuroprotection
- Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage
- Primate analogue of the Wisconsin Card Sorting Test: effects of excitotoxic lesions of the prefrontal cortex in the marmoset.
- Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge
- Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration
- Retrograde abolition of conditional fear after excitotoxic lesions in the basolateral amygdala of rats: absence of a temporal gradient.
- Age‐dependent striatal excitotoxic lesions produced by the endogenous mitochondrial inhibitor malonate
- Rethinking the excitotoxic ionic milieu: the emerging role of Zn 2+ in ischemic neuronal injury
- Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death
- Central role of microglia in neonatal excitotoxic lesions of the murine periventricular white matter
- excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement
- Transforming Growth Factor-β1-Mediated Neuroprotection against excitotoxic Injury in Vivo
- Intracellular calcium concentrations during” chemical hypoxia” and excitotoxic neuronal injury
- Comparing deficits following excitotoxic and contusion injuries in the thoracic and lumbar spinal cord of the adult rat
- excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis
- Activation of calpain I converts excitotoxic neuron death into a caspase-independent cell death
- Uric acid protects neurons against excitotoxic and metabolic insults in cell culture, and against focal ischemic brain injury in vivo
- Increased brain damage after stroke or excitotoxic seizures in melatonin‐deficient rats
- Effect of excitotoxic lesions of rat medial prefrontal cortex on spatial memory
- Dissociating context and space within the hippocampus: effects of complete, dorsal, and ventral excitotoxic hippocampal lesions on conditioned freezing and spatial …
- The ALIAmide palmitoylethanolamide and cannabinoids, but not anandamide, are protective in a delayed postglutamate paradigm of excitotoxic death in cerebellar …
- Lack of the p50 subunit of nuclear factor-κB increases the vulnerability of hippocampal neurons to excitotoxic injury
- Inhibition of succinate dehydrogenase by malonic acid produces an “excitotoxic” lesion in rat striatum
- Cell cycle regulators in neuronal death evoked by excitotoxic stress: implications for neurodegeneration and its treatment
- A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid β‐peptide
- Synaptic regeneration and functional recovery after excitotoxic injury in the guinea pig cochlea.
- Delayed mitochondrial dysfunction in excitotoxic neuron death: cytochrome c release and a secondary increase in superoxide production
- Both pre-and posttraining excitotoxic lesions of the basolateral amygdala abolish the expression of olfactory and contextual fear conditioning.
- Neuronal, astroglial and microglial cytokine expression after an excitotoxic lesion in the immature rat brain
- Distinct roles for sodium, chloride, and calcium in excitotoxic dendritic injury and recovery
- AMPA-induced excitotoxic lesions of the basal forebrain: a significant role for the cortical cholinergic system in attentional function
- Aggravation of acute ischemic stroke by hyperthermia is related to an excitotoxic mechanism
- Neurotoxic responses by microglia elicited by excitotoxic injury in the mouse hippocampus
- Vasoactive intestinal peptide prevents excitotoxic cell death in the murine developing brain.
- Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat
- CREB and NF-κB transcription factors regulate sensitivity to excitotoxic and oxidative stress induced neuronal cell death
- Selective excitotoxic degeneration of adult pig retinal ganglion cells in vitro
- Poly (ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death
- excitotoxic lesions of basal forebrain cholinergic neurons: effects on learning, memory and attention
- Behavioral effects of excitotoxic lesions of ventral medial prefrontal cortex in the rat are hemisphere-dependent
- Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats
- excitotoxic lesions of the amygdala fail to produce impairment in visual learning for auditory secondary reinforcement but interfere with reinforcer devaluation effects in …
- excitotoxic lesions of the prelimbic‐infralimbic areas of the rodent prefrontal cortex disrupt motor preparatory processes
- Protection of the neostriatum against excitotoxic damage by neurotrophin-producing, genetically modified neural stem cells
- β‐Amyloid neurotoxicity is mediated by a glutamate‐triggered excitotoxic cascade in rat nucleus basalis
- NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults
- Non‐NMDA and NMDA receptor‐mediated excitotoxic neuronal deaths in adult brain are morphologically distinct: further evidence for an apoptosis‐necrosis …
- Role of P2X7 Receptors in Ischemic and excitotoxic Brain Injury In Vivo
- The PSD95–nNOS interface: a target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death
- Carnosine protects against excitotoxic cell death independently of effects on reactive oxygen species
- A transforming growth factor-β antagonist unmasks the neuroprotective role of this endogenous cytokine in excitotoxic and ischemic brain injury
- Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine
- Thalamic retrograde degeneration following cortical injury: an excitotoxic process?
- The effects of dexmedetomidine on perinatal excitotoxic brain injury are mediated by the α2A-adrenoceptor subtype
- Cerebrospinal fluid studies in children with cerebral malaria: an excitotoxic mechanism?
- Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury
- Characteristics of acute and chronic kainate excitotoxic damage to the optic nerve
- Effects of selective excitotoxic lesions of the nucleus accumbens core, anterior cingulate cortex, and central nucleus of the amygdala on autoshaping performance in …
- Cell-permeant Ca2+ chelators reduce early excitotoxic and ischemic neuronal injury in vitro and in vivo
- Effects of interleukin-10 (IL-10) on pain behavior and gene expression following excitotoxic spinal cord injury in the rat
- excitotoxic lesions of the pedunculopontine tegmental nucleus produce contralateral hemiparkinsonism in the monkey
- Protective effect of parvalbumin on excitotoxic motor neuron death
- Post‐training excitotoxic lesions of the dorsal hippocampus attenuate forward trace, backward trace, and delay fear conditioning in a temporally specific manner
- Cellular defenses against excitotoxic insults
- Eugenol protects neuronal cells from excitotoxic and oxidative injury in primary cortical cultures
- Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation
- Asymmetrical motor behavior in rats with unilateral striatal excitotoxic lesions as revealed by the elevated body swing test
- Micromolar L-glutamate induces extensive apoptosis in an apoptotic-necrotic continuum of insult-dependent, excitotoxic injury in cultured cortical neurones
- On the excitotoxic properties of quinolinic acid, 2, 3-piperidine dicarboxylic acids and structurally related compounds
- A microtiter trypan blue absorbance assay for the quantitative determination of excitotoxic neuronal injury in cell culture
- Glial changes following an excitotoxic lesion in the CNS—I. Microglia/macrophages
- Effects of α2-Adrenoceptor Agonists on Perinatal excitotoxic Brain Injury: Comparison of Clonidine and Dexmedetomidine
- L-homocysteic acid: an endogenous excitotoxic ligand of the NMDA receptor
- Apolipoprotein E expression by neurons surviving excitotoxic stress
- Glial changes following an excitotoxic lesion in the CNS—II. Astrocytes
- Neuroprotective effects of interleukin-10 following excitotoxic spinal cord injury
- Calpain mediates excitotoxic DNA fragmentation via mitochondrial pathways in adult brains: evidence from calpastatin mutant mice
- Neuroprotective effect of developmental docosahexaenoic acid supplement against excitotoxic brain damage in infant rats
- Effects of selective excitotoxic prefrontal lesions on acquisition of nonmatching‐and matching‐to‐place in the T‐maze in the rat: Differential involvement of the …
- excitotoxic brain damage in the rat induces interleukin‐1β protein in microglia and astrocytes: Correlation with the progression of cell death
- Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis
- Specific antagonism of excitotoxic action of ‘uncommon’amino acids assayed in organotypic mouse cortical cultures
- Hemoglobin potentiates excitotoxic injury in cortical cell culture
- Cell type-specific roles for tissue plasminogen activator released by neurons or microglia after excitotoxic injury
- Selective excitotoxic pathology in the rat hippocampus
- excitotoxic septal lesions result in spatial memory deficits and altered flexibility of hippocampal single-unit representations
- excitotoxic calcium overload in a subpopulation of mitochondria triggers delayed death in hippocampal neurons
- BDNF-induced white matter neuroprotection and stage-dependent neuronal survival following a neonatal excitotoxic challenge
- Neuroprotection by neurotrophins and GDNF family members in the excitotoxic model of Huntington’s disease
- Topiramate prevents excitotoxic damage in the newborn rodent brain
- Differential effects of excitotoxic lesions of the basolateral amygdala, ventral subiculum and medial prefrontal cortex on responding with conditioned reinforcement and …
- Guanosine enhances glutamate uptake in brain cortical slices at normal and excitotoxic conditions
- Release of TNF alpha in the rat hippocampus following epileptic seizures and excitotoxic neuronal damage.
- Bioluminescence imaging of Smad signaling in living mice shows correlation with excitotoxic neurodegeneration
- δ-, but not μ-and κ-, opioid receptor activation protects neocortical neurons from glutamate-induced excitotoxic injury
- Dual-gene, dual-cell type therapy against an excitotoxic insult by bolstering neuroenergetics
- Transient expression of the NG2 proteoglycan by a subpopulation of activated macrophages in an excitotoxic hippocampal lesion
- excitotoxic and post-ischemic neurodegeneration: Involvement of transglutaminases
- Selective activation of mGlu4 metabotropic glutamate receptors is protective against excitotoxic neuronal death
- Alterations in dendritic morphology of prefrontal cortical and nucleus accumbens neurons in post-pubertal rats after neonatal excitotoxic lesions of the ventral …
- Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators
- Prolonged exposure to submicromolar concentrations of quinolinic acid causes excitotoxic damage in organotypic cultures of rat corticostriatal system
- excitotoxic lesions of the medial prefrontal cortex attenuate fear responses in the elevated-plus maze, social interaction and shock probe burying tests
- Perseveration and strategy in a novel spatial self-ordered sequencing task for nonhuman primates: effects of excitotoxic lesions and dopamine depletions of the …
- Vinpocetin protects against excitotoxic cell death in primary cultures of rat cerebral cortex
- Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington’s disease, as demonstrated by adenoviral gene …
- Quantitative analysis of the generation of different striatal neuronal subtypes in the adult brain following excitotoxic injury
- Behavioral and morphological alterations following neonatal excitotoxic lesions of the medial prefrontal cortex in rats
- excitotoxic neuronal damage and neuropsychiatric disorders
- Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid β‐peptide toxicity
- excitotoxic oligodendrocyte death and axonal damage induced by glutamate transporter inhibition
- Paraquat induces long-lasting dopamine overflow through the excitotoxic pathway in the striatum of freely moving rats
- The effect of excitotoxic lesions centered on the hippocampus or perirhinal cortex in object recognition and spatial memory tasks.
- Nitric oxide mediates neurodegeneration and breakdown of the blood-brain barrier in tPA-dependent excitotoxic injury in mice
- excitotoxic lesions of the hippocampus disrupt runway but not consummatory contrast
- excitotoxic mechanisms in the pathogenesis of dementia
- Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate
- Specific neuronal protein: a new tool for histological evaluation of excitotoxic lesions
- Altered sexual partner preference in male ferrets given excitotoxic lesions of the preoptic area/anterior hypothalamus
- A primate model of Huntington’s disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon
- Mitochondrial uncoupling protein‐2 protects the immature brain from excitotoxic neuronal death
- Proton magnetic resonance spectroscopy in Huntington’s disease: Evidence in favour of the glutamate excitotoxic theory?
- Hypoxic and excitotoxic damage to cultured rat retinal ganglion cells
- excitotoxic acid lesions of the primate subthalamic nucleus result in transient dyskinesias of the contralateral limbs
- Differential oxidative stress in oligodendrocytes and neurons after excitotoxic insults and protection by natural polyphenols
- Caspase-mediated degradation of AMPA receptor subunits: a mechanism for preventing excitotoxic necrosis and ensuring apoptosis
- Comparison of excitotoxic profiles of ATPA, AMPA, KA and NMDA in organotypic hippocampal slice cultures
- A specific form of cognitive rigidity following excitotoxic lesions of the basal forebrain in marmosets
- Selective putaminal excitotoxic lesions in non-human primates model the movement disorder of Huntington disease
- Cholinergic system and memory in the rat: effects of chronic ethanol, embryonic basal forebrain brain transplants and excitotoxic lesions of cholinergic basal forebrain …
- excitotoxic cytopathology, progression, and reversibility of thiamine deficiency-induced diencephalic lesions
- excitotoxic mitochondrial depolarisation requires both calcium and nitric oxide in rat hippocampal neurons
- excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons
- excitotoxic cell death dependent on inhibitory receptor activation
- … a reactive oxygen species (ROS)-dependent fashion and can operate as a ROS scavenger and as a respiratory substrate in cerebellar neurons undergoing excitotoxic …
- Domoic acid: a dementia-inducing excitotoxic food poison with kainic acid receptor specificity
- Apoptosis in substantia nigra following developmental striatal excitotoxic injury
- Erythropoietin is neuroprotective against NMDA-receptor-mediated excitotoxic brain injury in newborn mice
- Wogonin inhibits excitotoxic and oxidative neuronal damage in primary cultured rat cortical cells
- Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage
- Effects of excitotoxic lesions of the basolateral amygdala on cocaine-seeking behavior and cocaine conditioned place preference in rats
- Müller cell swelling, glutamate uptake, and excitotoxic neurodegeneration in the isolated rat retina
- Reactive astrocytosis from excitotoxic injury in hippocampal organ culture parallels that seen in vivo
- Changes in the diffusion of water and intracellular metabolites after excitotoxic injury and global ischemia in neonatal rat brain
- Enhanced drinking after excitotoxic lesions of the parabrachial nucleus in the rat
- Glucocorticoids, stress and exacerbation of excitotoxic neuron death
- excitotoxic versus apoptotic mechanisms of neuronal cell death in perinatal hypoxia/ischemia
- Subchronic treatment with haloperidol and clozapine in rats with neonatal excitotoxic hippocampal damage
- Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration
- Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective
- excitotoxic amino acid injections into the medial amygdala facilitate maternal behavior in virgin female rats
- excitotoxic lesions of the rat medial prefrontal cortex: effects on abnormal behaviors associated with neonatal hippocampal damage
- Dependence of excitotoxic neurodegeneration on mitochondrial aconitase inactivation
- Rolipram reduces excitotoxic neuronal damage
- Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina
- Differential effects of excitotoxic lesions of the amygdala on cocaine-induced conditioned locomotion and conditioned place preference
- Spatial and associative learning deficits induced by neonatal excitotoxic hippocampal damage in rats: further evaluation of an animal model of schizophrenia
- Time course of glial proliferation and glial apoptosis following excitotoxic CNS injury
- The hippocampus and appetitive Pavlovian conditioning: effects of excitotoxic hippocampal lesions on conditioned locomotor activity and autoshaping
- Intracerebral implantation of NGF-releasing biodegradable microspheres protects striatum against excitotoxic damage
- Vampire bat salivary plasminogen activator (desmoteplase) inhibits tissue-type plasminogen activator-induced potentiation of excitotoxic injury
- Calpain activation contributes to dendritic remodeling after brief excitotoxic injury in vitro
- Effects of excitotoxic lesions in the ventral striatopallidal–thalamocortical pathway on odor reversal learning: inability to extinguish an incorrect response
- Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: acute excitotoxic necrosis and delayed apoptosis
- Nitric oxide and S‐nitrosylation: excitotoxic and cell signaling mechanism
- Perinatal hypoxia-ischemia induces apoptotic and excitotoxic death of periventricular white matter oligodendrocyte progenitors
- excitotoxic injury to mitochondria isolated from cultured neurons
- Memantine is highly potent in protecting cortical cultures against excitotoxic cell death evoked by glutamate and N-methyl-D-aspartate
- Proinflammatory cytokines and interleukin‐9 exacerbate excitotoxic lesions of the newborn murine neopallium
- Synaptic activity becomes excitotoxic in neurons exposed to elevated levels of platelet-activating factor
- Testosterone amplifies excitotoxic damage of cultured oligodendrocytes
- Differential blood–brain barrier breakdown and leucocyte recruitment following excitotoxic lesions in juvenile and adult rats
- Induction of GABAergic phenotype in a neural stem cell line for transplantation in an excitotoxic model of Huntington’s disease
- Neuronal death and blood–brain barrier breakdown after excitotoxic injury are independent processes
- Comparative behavioral changes between male and female postpubertal rats following neonatal excitotoxic lesions of the ventral hippocampus
- Endogenous methylarginines regulate neuronal nitric-oxide synthase and prevent excitotoxic injury
- Enhanced nucleus accumbens dopamine and plasma corticosterone stress responses in adult rats with neonatal excitotoxic lesions to the medial prefrontal cortex
- 21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures
- Low-dose ouabain protects against excitotoxic apoptosis and up-regulates nuclear Bcl-2 in vivo
- excitotoxic lesions of the core and shell subregions of the nucleus accumbens differentially disrupt body weight regulation and motor activity in rat
- The nature and timing of excitotoxic neuronal necrosis in the cerebral cortex, hippocampus and thalamus due to flurothyl-induced status epilepticus
- Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries
- Inhibition of free radical production or free radical scavenging protects from the excitotoxic cell death mediated by glutamate in cultures of cerebellar granule neurons
- excitotoxic food additives: functional teratological aspects
- N‐methyl‐D‐aspartate receptor‐mediated mitochondrial Ca2+ overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after …
- Transcription of the NR1 subunit of the N-methyl-D-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia
- Effects of biologically delivered NGF, BDNF and bFGF on striatal excitotoxic lesions.
- Antioxidant treatment protects striatal neurons against excitotoxic insults
- Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death
- excitotoxic destruction facilitates brain tumor growth
- Nervous system-specific expression of a novel serine protease: regulation in the adult rat spinal cord by excitotoxic injury
- Growth factors protect neurons against excitotoxic/ischemic damage by stabilizing calcium homeostasis.
- Urocortin, but not urocortin II, protects cultured hippocampal neurons from oxidative and excitotoxic cell death via corticotropin-releasing hormone receptor type I
- Antagonists for group I mGluRs attenuate excitotoxic neuronal death in cortical cultures
- excitotoxic lesions of the parabrachial nuclei prevent conditioned taste aversions and sodium appetite in rats.
- Enhanced amphetamine sensitivity and increased expression of dopamine D2 receptors in postpubertal rats after neonatal excitotoxic lesions of the medial prefrontal …
- Short-term lithium treatment promotes neuronal survival and proliferation in rat striatum infused with quinolinic acid, an excitotoxic model of Huntington’s …
- excitotoxic cell death
- Nociceptin/orphanin FQ exacerbates excitotoxic white-matter lesions in the murine neonatal brain
- The effects of excitotoxic lesions of the nucleus accumbens core or shell regions on intravenous heroin self-administration in rats
- BDNF heightens the sensitivity of motor neurons to excitotoxic insults through activation of TrkB
- Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death
- The effects of excitotoxic lesion of the medial prefrontal cortex on latent inhibition, prepulse inhibition, food hoarding, elevated plus maze, active avoidance and …
- excitotoxic mechanism of cell swelling in rat cerebral cortical slices treated acutely with ammonia
- excitotoxic neuronal injury in chronic homocysteine neurotoxicity studied in vitro: the role of NMDA and group I metabotropic glutamate receptors
- Kynurenergic manipulations influence excitatory synaptic function and excitotoxic vulnerability in the rat hippocampus in vivo
- High-affinity calcium indicators underestimate increases in intracellular calcium concentrations associated with excitotoxic glutamate stimulations
- Dimethyl sulfoxide suppresses NMDA-and AMPA-induced ion currents and calcium influx and protects against excitotoxic death in hippocampal neurons
- S100B potently activates p65/c-Rel transcriptional complexes in hippocampal neurons: clinical implications for the role of S100B in excitotoxic brain injury
- Learning disturbances following excitotoxic lesion of cholinergic pedunculo-pontine nucleus in the rat
- Calretinin and calbindin D-28k delay the onset of cell death after excitotoxic stimulation in transfected P19 cells
- The critical role of calpain versus caspase activation in excitotoxic injury induced by nitric oxide
- Mitochondrial peroxiredoxin‐3 protects hippocampal neurons from excitotoxic injury in vivo
- Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo
- Dissociation of function within the hippocampus: effects of dorsal, ventral and complete excitotoxic hippocampal lesions on spatial navigation
- excitotoxic brain damage involves early peroxynitrite formation in a model of Huntington’s disease in rats: protective role of iron porphyrinate 5, 10, 15, 20-tetrakis (4 …
- excitotoxic mechanisms may be involved in the pathophysiology of tardive dyskinesia.
- Tf-lipoplex-mediated NGF gene transfer to the CNS: neuronal protection and recovery in an excitotoxic model of brain injury
- Endocannabinoids potently protect the newborn brain against AMPA‐kainate receptor‐mediated excitotoxic damage
- Effects of interleukin-10 on neonatal excitotoxic brain lesions in mice
- Oral treatment with rofecoxib reduces hippocampal excitotoxic neurodegeneration
- excitotoxic acid lesions of the primate subthalamic nucleus result in reduced pallidal neuronal activity during active holding
- … minocycline plus pyruvate treatment enhances effects of each agent to inhibit inflammation, oxidative damage, and neuronal loss in an excitotoxic animal model of …
- Interleukin‐1β and the interleukin‐1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat
- Barbiturates induce mitochondrial depolarization and potentiate excitotoxic neuronal death
- Neural cell adhesion molecule L1-transfected embryonic stem cells promote functional recovery after excitotoxic lesion of the mouse striatum
- The effect of excitotoxic hippocampal lesions on simple and conditional discrimination learning in the rat
- Activation of the ERK1/2 signaling cascade by excitotoxic spinal cord injury
- Anti-excitotoxic actions of taurine in the rat hippocampus studied in vivo and in vitro
- excitotoxic neurodegeneration induced by intranasal administration of kainic acid in C57BL/6 mice
- Selected peptides targeted to the NMDA receptor channel protect neurons from excitotoxic death
- The effects of excitotoxic lesions of the basal forebrain on the acquisition, retention and serial reversal of visual discriminations in marmosets
- Nitric oxide mediates excitotoxic and anoxic damage in rat retinal ganglion cells cocultured with astroglia
- Delayed excitotoxic neurodegeneration induced by excitatory amino acid agonists in isolated retina
- The effect of streptozotocin-induced diabetes on the release of excitotoxic and other amino acids from the ischemic rat cerebral cortex
- Impaired delayed spatial win-shift behaviour on the eight arm radial maze following excitotoxic lesions of the medial prefrontal cortex in the rat
- … factors [activity-dependent neurotrophic factor (ADNF) and basic fibroblast growth factor (bFGF)] interrupt excitotoxic neurodegenerative cascades promoted by a PS1 …
- Dissociable effects on spatial maze and passive avoidance acquisition and retention following AMPA-and ibotenic acid-induced excitotoxic lesions of the basal …
- Oncostatin M is a neuroprotective cytokine that inhibits excitotoxic injury in vitro and in vivo
- Enhancement of amphetamine-induced locomotor activity and dopamine release in nucleus accumbens following excitotoxic lesions of the hippocampus
- excitotoxic amino acids
- excitotoxic activation of the NMDA receptor results in inhibition of calcium/calmodulin kinase II activity in cultured hippocampal neurons
- Imaging of primary and remote ischaemic and excitotoxic brain lesions. An autoradiographic study of peripheral type benzodiazepine binding sites in the rat and cat
- The identification and characterization of excitotoxic nerve-endings in Alzheimer disease
- Evidence for proteolytic cleavage of brevican by the ADAMTSs in the dentate gyrus after excitotoxic lesion of the mouse entorhinal cortex
- Neonatal hypoxic-ischemic or excitotoxic striatal injury results in a decreased adult number of substantia nigra neurons
- The effects of excitotoxic lesions of the nucleus accumbens on a matching to position task
- Effects of excitotoxic lesions of the basal forebrain on MFB self-stimulation
- The excitotoxic concept
- excitotoxic death of a subset of embryonic rat motor neurons in vitro
- Cu/Zn superoxide dismutase expression in the postnatal rat brain following an excitotoxic injury
- Apoptosis and necrosis occurring in excitotoxic cell death in isolated chick embryo retina
- Acute excitotoxic injury induces expression of monocyte chemoattractant protein-1 and its receptor, CCR2, in neonatal rat brain
- Implication of NMDA type glutamate receptors in neural regeneration and neoformation of synapses after excitotoxic injury in the guinea pig cochlea
- Lentiviral‐mediated gene transfer of brain‐derived neurotrophic factor is neuroprotective in a mouse model of neonatal excitotoxic challenge
- The anti-excitotoxic effects of certain anesthetics, analgesics and sedative-hypnotics
- p53 is present in synapses where it mediates mitochondrial dysfunction and synaptic degeneration in response to DNA damage, and oxidative and excitotoxic insults
- The CNS acute inflammatory response to excitotoxic neuronal cell death
- Effects of excitotoxic lesions of the rat ventral striatum on the perception of reward cost
- Ultrastructure of excitotoxic neuronal death in murine cortical culture
- Loss of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus: rescue by neurotrophins
- Inhibition by anion channel blockers of ischemia-evoked release of excitotoxic and other amino acids from rat cerebral cortex
- Selective excitotoxic lesions of the hippocampus and basolateral amygdala have dissociable effects on appetitive cue and place conditioning based on path …
- Astrocytic factors protect neuronal integrity and reduce microglial activation in an in vitro model of N‐methyl‐d‐aspartate‐induced excitotoxic injury in organotypic …
- Inhibition of excitotoxic neuronal death by methanol extract of Acori graminei rhizoma in cultured rat cortical neurons
- Non-invasive neurochemical analysis of focal excitotoxic lesions in models of neurodegenerative illness using spectroscopic imaging
- excitotoxic lesions of the pre‐and parasubiculum disrupt the place fields of hippocampal pyramidal cells
- Neuronal protein kinase signaling cascades and excitotoxic cell death
- Selective vulnerability of the CA1 region of hippocampus to the indirect excitotoxic effects of malonic acid
- The effects of endogenous interleukin-10 on gray matter damage and the development of pain behaviors following excitotoxic spinal cord injury in the mouse
- Activated microglial cells migrate towards sites of excitotoxic neuronal injury inside organotypic hippocampal slice cultures
- AMPA receptors are the major mediators of excitotoxic death in mature oligodendrocytes
- Topiramate reduces excitotoxic and ischemic injury in the rat retina
- Effects of excitotoxic lesions of the central amygdaloid nucleus on the potentiation of reward-related stimuli by intra-accumbens amphetamine
- Thalamic amnesia reconsidered: excitotoxic lesions of the intralaminar nuclei, but not the mediodorsal nucleus, disrupt place delayed matching-to-sample …
- Extragonadal synthesis of estradiol is protective against kainic acid excitotoxic damage to the hippocampus
- Platelet-derived growth factor-BB pretreatment attenuates excitotoxic death in cultured hippocampal neurons
- Neurons are protected from excitotoxic death by p53 antisense oligonucleotides delivered in anionic liposomes
- Gas1 is induced during and participates in excitotoxic neuronal death
- Potent protection of ferulic acid against excitotoxic effects of maternal intragastric administration of monosodium glutamate at a late stage of pregnancy on developing …
- excitotoxic death induced by released glutamate in depolarized primary cultures of mouse cerebellar granule cells is dependent on GABAA receptors and niflumic …
- The selective cyclooxygenase-2 inhibitor rofecoxib suppresses brain inflammation and protects cholinergic neurons from excitotoxic degeneration in vivo
- Effects of excitotoxic lesions of the basolateral amygdala on conditional discrimination learning with primary and conditioned reinforcement
- NMDA and non-NMDA receptor antagonists protect against excitotoxic injury in the rat spinal cord
- Dopaminergic neurotoxins require excitotoxic stimulation in organotypic cultures
- Calcium buffering and protection from excitotoxic cell death by exogenous calbindin-D28k in HEK 293 cells
- Comparative effects of excitotoxic lesions of the hippocampus and septum/diagonal band on conditional visual discrimination and spatial learning
- Disruption of Pavlovian contextual conditioning by excitotoxic lesions of the nucleus accumbens core.
- Microglial expression of prostaglandin EP3 receptor in excitotoxic lesions in the rat striatum
- Aminooxyacetic acid produces excitotoxic lesions in the rat striatum
- The influence of excitotoxic basal ganglia lesions on motor performance in the common marmoset
- excitotoxic lesions centered on perirhinal cortex produce delay-dependent deficits in a test of spatial memory.
- Recombinant peroxiredoxin 5 protects against excitotoxic brain lesions in newborn mice
- Mice transgenically overexpressing sulfonylurea receptor 1 in forebrain resist seizure induction and excitotoxic neuron death
- excitotoxic cell death and delayed rescue in human neurons derived from NT2 cells
- Contribution of endogenous glycine site NMDA agonists to excitotoxic retinal damage in vivo
- The role of excitotoxic injury in post-traumatic syringomyelia
- Diffusion-weighted MR imaging in a rat model of syringomyelia after excitotoxic spinal cord injury
- Changes in sleep–waking cycle after striatal excitotoxic lesions
- Iodoacetate produces striatal excitotoxic lesions
- Protection provided by cyclosporin A against excitotoxic neuronal death is genotype dependent
- Up-regulation of Eph tyrosine kinase receptors after excitotoxic injury in adult hippocampus
- excitotoxic lesions of the septum produce anxiolytic effects in the elevated plus-maze and the shock-probe burying tests
- GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults
- Local protective effects of nerve growth factor-secreting fibroblasts against excitotoxic lesions in the rat striatum
- … and dysfunctions of the nucleus basalis as Alzheimer’s disease models: general and critical overview and analysis of the long-term changes in several excitotoxic …
- Selective excitotoxic lesions of the nucleus accumbens core and shell differentially affect aversive Pavlovian conditioning to discrete and contextual cues
- Protective effects of PACAP in excitotoxic striatal lesion
- Heparin-binding epidermal growth factor-like growth factor in hippocampus: modulation of expression by seizures and anti-excitotoxic action
- Platelet‐activating factor antagonists reduce excitotoxic damage in cultured neurons from embryonic chick telencephalon and protect the rat hippocampus and …
- Flupirtine protects neurons against excitotoxic or ischemic damage and inhibits the increase in cytosolic Ca2+ concentration
- Chronic, selective forebrain responses to excitotoxic dorsal horn injury
- excitotoxic neuronal injury in acute homocysteine neurotoxicity: role of calcium and mitochondrial alterations
- excitotoxic brain injury stimulates expression of the chemokine receptor CCR5 in neonatal rats
- The effect of excitotoxic lesions centered on the perirhinal cortex in two versions of the radial arm maze task.
- Contingent versus incidental context processing during conditioning: dissociation after excitotoxic hippocampal plus dentate gyrus lesions
- Tumor necrosis factor α increases neuronal vulnerability to excitotoxic necrosis by inducing expression of the AMPA–glutamate receptor subunit GluR1 via an acid …
- GABA accelerates excitotoxic cell death in cortical cultures: protection by blockers of GABA-gated chloride channels
- excitotoxic damage in traumatic brain injury
- Multiple pathways of neuroprotection against oxidative stress and excitotoxic injury in immature primary hippocampal neurons
- Naproxen reduces excitotoxic neurodegeneration in vivo with an extended therapeutic window
- Effects of laterodorsal tegmentum excitotoxic lesions on behavioral and dopamine responses evoked by morphine and d-amphetamine
- Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre‐ and postsynaptic sites in the rat striatum
- Comparative behavioral changes in postpubertal rats after neonatal excitotoxic lesions of the ventral hippocampus and the prefrontal cortex
- Interpretation of intrinsic optical signals and calcein fluorescence during acute excitotoxic insult in the hippocampal slice
- excitotoxic lesions of the pre-and parasubiculum disrupt object recognition and spatial memory processes.
- excitotoxic neurodegeneration induced by deprivation of oxygen and glucose in isolated retina.
- Calpain I activation in rat hippocampal neurons in culture is NMDA receptor selective and not essential for excitotoxic cell death
- Ca2+-independent excitotoxic neurodegeneration in isolated retina, an intact neural net: a role for Cl− and inhibitory transmitters
- Neonatal excitotoxic ventral hippocampal damage alters dopamine response to mild repeated stress and to chronic haloperidol
- Both electrolytic and excitotoxic lesions of nucleus accumbens disrupt latent inhibition of learning in rats
- Striatal modulation of cAMP‐response‐element‐binding protein (CREB) after excitotoxic lesions: implications with neuronal vulnerability in Huntington’s disease
- Monocyte chemoattractant protein-1 is a mediator of acute excitotoxic injury in neonatal rat brain
- Brain‐derived neurotrophic factor induces excitotoxic sensitivity in cultured embryonic rat spinal motor neurons through activation of the phosphatidylinositol 3‐kinase …
- Convection-enhanced selective excitotoxic ablation of the neurons of the globus pallidus internus for treatment of parkinsonism in nonhuman primates
- Differential effects of excitotoxic basolateral and corticomedial lesions of the amygdala on the behavioural and endocrine responses to either sexual or aggression …
- excitotoxic lesions of the hippocampus leave sensory preconditioning intact: Implications for models of hippocampal functioning.
- Opposite effects of TGF-β1 on rapidly-and slowly-triggered excitotoxic injury
- Primary CA1 and conditionally immortal MHP36 cell grafts restore conditional discrimination learning and recall in marmosets after excitotoxic lesions of the …
- Developmental spectrum of the excitotoxic cascade induced by ibotenate: a model of hypoxic insults in fetuses and neonates
- Increase in ferric and ferrous iron in the rat hippocampus with time after kainate-induced excitotoxic injury
- Intrinsic neurons of fastigial nucleus mediate neurogenic neuroprotection against excitotoxic and ischemic neuronal injury in rat
- Discriminable excitotoxic effects of ibotenic acid, AMPA, NMDA and quinolinic acid in the rat laterodorsal tegmental nucleus
- Transplanted human embryonic germ cell‐derived neural stem cells replace neurons and oligodendrocytes in the forebrain of neonatal mice with excitotoxic brain …
- Effects of excitotoxic brain lesions on taste-mediated odor learning in the rat
- excitotoxic lesions of the pedunculopontine tegmental nucleus of the rat. II. Examination of eating and drinking, rotation, and reaching and grasping following …
- Changes in secondary glutamate release underlie the developmental regulation of excitotoxic neuronal cell death
- Effects of cholinergic-rich neural grafts on radial maze performance of rats after excitotoxic lesions of the forebrain cholinergic projection system—II. Cholinergic drugs …
- Mechanistic distinctions between excitotoxic and acidotic hippocampal damage in an in vitro model of ischemia
- Tissue inhibitor of metalloproteinase 1 inhibits excitotoxic cell death in neurons
- excitotoxic lesion of rat brain with quinolinic acid induces expression of p53 messenger RNA and protein and p53-inducible genes Bax and Gadd-45 in brain areas …
- BDNF, and full length and truncated TrkB expression in the hippocampus of the rat following kainic acid excitotoxic damage. Evidence of complex time-dependent and …
- Gustatory functions, sodium appetite, and conditioned taste aversion survive excitotoxic lesions of the thalamic taste area.
- Conditions affecting the onset, severity, and progression of a spontaneous pain-like behavior after excitotoxic spinal cord injury
- Hypoxia induces an excitotoxic-type of dark cell degeneration in cerebellar Purkinje neurons
- Evaluation of the pathologic characteristics of excitotoxic spinal cord injury with MR imaging
- 2‐deoxy‐d‐glucose protects hippocampal neurons against excitotoxic and oxidative injury: Evidence for the involvement of stress proteins
- excitotoxic mechanisms in hypoglycaemic hippocampal injury
- The selective p38 inhibitor SB-239063 protects primary neurons from mild to moderate excitotoxic injury
- Glial cell line-derived neurotrophic factor protects striatal calbindin-immunoreactive neurons from excitotoxic damage
- excitotoxic lesions of the pedunculopontine tegmental nucleus in rats impair performance on a test of sustained attention
- The effects of excitotoxic lesions of the basolateral amygdala on the acquisition of heroin-seeking behaviour in rats
- The effects of excitotoxic lesions of the substantia innominata, ventral and dorsal globus pallidus on the acquisition and retention of a conditional visual discrimination …
- Neuroprotective cannabinoid receptor antagonist SR141716A prevents downregulation of excitotoxic NMDA receptors in the ischemic penumbra
- excitotoxic food additives–relevance of animal studies to human safety.
- Interleukin‐1β exacerbates and interleukin‐1 receptor antagonist attenuates neuronal injury and microglial activation after excitotoxic damage in organotypic …
- Chronic multichannel recordings from organotypic hippocampal slice cultures: protection from excitotoxic effects of NMDA by non-competitive NMDA antagonists
- Fenamates protect neurons against ischemic and excitotoxic injury in chick embryo retina
- Rapid appearance of β-amyloid precursor protein immunoreactivity in glial cells follwing excitotoxic brain injury
- Brain-derived neurotrophic factor prevents the loss of nigral neurons induced by excitotoxic striatal-pallidal lesions
- Are human neurodegenerative disorders linked to environmental chemicals with excitotoxic properties?
- Glutamate-mediated excitotoxic death of cultured striatal neurons is mediated by non-NMDA receptors
- Adrenocorticosteroid receptor blockade and excitotoxic challenge regulate adrenocorticosteroid receptor mRNA levels in hippocampus
- excitotoxic and metabolic damage to the rodent striatum: role of the P75 neurotrophin receptor and glial progenitors
- Atrophy of cholinergic basal forebrain neurons following excitotoxic cortical lesions is reversed by intravenous administration of an NGF conjugate
- excitotoxic preconditioning elicited by both glutamate and hypoxia and abolished by lactate transport inhibition in rat hippocampal slices
- Late N‐methyl‐d‐aspartate receptor blockade rescues hippocampal neurons from excitotoxic stress and death after 4‐aminopyridine‐induced epilepsy
- SIN‐1‐induced cytotoxicity in mixed cortical cell culture: peroxynitrite‐dependent and‐independent induction of excitotoxic cell death
- Are NMDA or AMPA/kainate receptor antagonists more efficacious in the delayed treatment of excitotoxic neuronal injury?
- … that laminin-10 is a major isoform in the mouse hippocampus and is degraded by the tissue plasminogen activator/plasmin protease cascade during excitotoxic injury
- excitotoxic hippocampal injury is attenuated in thioredoxin transgenic mice
- Intrinsic optical signaling denoting neuronal damage in response to acute excitotoxic insult by domoic acid in the hippocampal slice
- Bright light suppresses hyperactivity induced by excitotoxic dorsal hippocampus lesions in the rat.
- Vulnerability to excitotoxic stimuli of cultured rat hippocampal neurons containing the calcium-binding proteins calretinin and calbindin D28K
- Comparative effects of levobupivacaine and racemic bupivacaine on excitotoxic neuronal death in culture and N-methyl-D-aspartate-induced seizures in mice
- excitotoxic injury stimulates pro-drug-induced 7-chlorokynurenate formation in the rat striatum in vivo
- Methylmalonic acid induces excitotoxic neuronal damage in vitro
- Increased amyloid precursor protein expression and serotonergic sprouting following excitotoxic lesion of the rat magnocellular nucleus basalis: neuroprotection by …
- excitotoxic hippocampal lesions disrupt allocentric spatial learning in mice: effects of strain and task demands
- Nitric oxide participates in excitotoxic mechanisms induced by chemical hypoxia
- Decrease of proinflammatory molecules correlates with neuroprotective effect of the fluorinated salicylate triflusal after postnatal excitotoxic damage
- Triflusal posttreatment inhibits glial nuclear factor-κB, downregulates the glial response, and is neuroprotective in an excitotoxic injury model in postnatal brain
- Amelioration of behavioral deficits in a rat model of Huntington’s disease by an excitotoxic lesion to the globus pallidus
- Neuronal expression of AP-1 proteins in excitotoxic-neurodegenerative disorders and following nerve fiber lesions
- VPAC2 receptors mediate vasoactive intestinal peptide-induced neuroprotection against neonatal excitotoxic brain lesions in mice
- Inhibition of cell cycle pathway by flavopiridol promotes survival of cerebellar granule cells after an excitotoxic treatment
- excitotoxic mechanisms of neurodegeneration in transmissible spongiform encephalopathies.
- Effects of agmatine, interleukin-10, and cyclosporin on spontaneous pain behavior after excitotoxic spinal cord injury in rats
- excitotoxic lesions of the gustatory thalamus eliminate consummatory but not instrumental successive negative contrast in rats
- excitotoxic degeneration of hypothalamic orexin neurons in slice culture
- Prevention of post-traumatic excitotoxic brain damage with NMDA antagonist drugs: a new strategy for the nineties
- Prostaglandin A1 protects striatal neurons against excitotoxic injury in rat striatum
- Contrasting effects of excitotoxic lesions of the prefrontal cortex on the behavioural response to D-amphetamine and presynaptic and postsynaptic measures of striatal …
- Spatial discrimination deficits by excitotoxic lesions in the Morris water escape task
- Prostate apoptosis response‐4 production in synaptic compartments following apoptotic and excitotoxic insults: evidence for a pivotal role in mitochondrial dysfunction …
- Quantitative analysis of microglial reaction to a cortical excitotoxic lesion in the early postnatal brain
- Glial expression of small heat shock proteins following an excitotoxic lesion in the immature rat brain
- Neuroprotection from NMDA excitotoxic lesion by Cu/Zn superoxide dismutase gene delivery to the postnatal rat brain by a modular protein vector
- Distinct roles for striatal subregions in mediating response processing revealed by focal excitotoxic lesions.
- Neurons derived from embryonic stem (ES) cells resemble normal neurons in their vulnerability to excitotoxic death
- Differential brain area vulnerability to long-term subcortical excitotoxic lesions
- Cortical neurons containing somatostatin‐or parvalbumin‐like immunoreactivity are atypically vulnerable to excitotoxic injury in vitro
- excitotoxic insults to the optic nerve alter visual evoked potentials
- The immunosuppressant mycophenolate mofetil attenuates neuronal damage after excitotoxic injury in hippocampal slice cultures
- Selective activation of group-II metabotropic glutamate receptors is protective against excitotoxic neuronal death
- Effects of excitotoxic amino acids on pituitary hormone secretion in the rat
- Susceptibilities to and mechanisms of excitotoxic cell death of adult mouse inner retinal neurons in dissociated culture
- Effects of adrenal medullary transplants on pain-related behaviors following excitotoxic spinal cord injury
- Apoptotic neuron death in rat substantia nigra induced by striatal excitotoxic injury is developmentally dependent
- (-)-Nicotine protects against systemic kainic acid-induced excitotoxic effects
- excitotoxic insult due to ibogaine leads to delayed induction of neuronal NOS in Purkinje cells.
- The severity of excitotoxic brain injury is dependent on brain temperature in immature rat
- Long-term evolution of excitotoxic cortical dysgenesis induced in the developing rat brain
- Rapid subcellular redistribution of Bax precedes caspase-3 and endonuclease activation during excitotoxic neuronal apoptosis in rat brain
- Chronic excitotoxic lesion of the dorsal raphe nucleus induces sodium appetite
- excitotoxic damage in neurotrauma: fact or fiction
- 17β-Estradiol enhances cortical cholinergic innervation and preserves synaptic density following excitotoxic lesions to the rat nucleus basalis magnocellularis
- Inhibition of TNF-α can attenuate or exacerbate excitotoxic injury in neonatal rat brain
- Early appearance of functional deficits after neonatal excitotoxic and hypoxic-ischemic injury: fragile recovery after development and role of the NMDA receptor
- Aminoglutethimide prevents excitotoxic and ischemic injuries in cortical neurons
- Endogenous brain-derived neurotrophic factor protects dopaminergic nigral neurons against transneuronal degeneration induced by striatal excitotoxic injury
- excitotoxic lesions of the rat entorhinal cortex. Effects of selective neuronal damage on acquisition and retention of a non-spatial reference memory task
- excitotoxic effect of kainic acid on chicken otoacoustic emissions and cochlear potentials
- excitotoxic lesions of the tegmental pedunculopontine nucleus impair copulation in naive male rats and block the rewarding effects of copulation in experienced male …
- excitotoxic effects of non-NMDA receptor agonists in organotypic corticostriatal slice cultures
- Calpain inhibitors prevent nitric oxide-triggered excitotoxic apoptosis
- VIP neuroprotection against excitotoxic lesions of the developing mouse brain
- Diltiazem protects against neurotoxicity induced by excitotoxic amino acids on cochlear afferent fibers
- N-methyl-D-aspartate receptor subunit expression and phosphorylation following excitotoxic spinal cord injury in rats
- excitotoxic lesions of the medial amygdala differentially disrupt prolactin secretory responses in cycling and mated female rats
- Role of zinc in blockade of excitotoxic action of quinolinic acid by picolinic acid
- excitotoxic swelling occurs in oxygen and glucose deprived human cortical slices
- Mitochondrial transmembrane potential and free radical production in excitotoxic neurodegeneration
- Effects of excitotoxic thalamic intralaminar nuclei lesions on attention and working memory
- The effects of excitotoxic lesions of the pedunculopontine tegmental nucleus on conditioned place preference to 4%, 12% and 20% sucrose solutions
- Systemic or local administration of azide produces striatal lesions by an energy impairment-induced excitotoxic mechanism
- Potentiation of excitotoxic injury by high concentrations of extracellular reduced glutathione
- NOS Expression in Nigral Cells after excitotoxic and Non‐excitotoxic Lesion of the Pedunculopontine Tegmental Nucleus
- Is the cuneiform nucleus a critical component of the mesencephalic locomotor region? An examination of the effects of excitotoxic lesions of the cuneiform nucleus on …
- gp120, a human immunodeficiency virus-1 coat protein, augments excitotoxic hippocampal injury in perinatal rats
- Effects of excitotoxic lesions of the central or basolateral nucleus of the amygdala on naloxone-precipitated withdrawal-induced conditioned place aversion in …
- excitotoxic lateral pallidotomy does not relieve L-DOPA-induced dyskinesia in MPTP parkinsonian monkeys
- Opioid peptide messenger RNA expression is increased at spinal and supraspinal levels following excitotoxic spinal cord injury
- The vulnerability of spinal cord neurons to excitotoxic injury: comparison with cortical neurons
- Galantamine-induced behavioral recovery after sublethal excitotoxic lesions to the rat medial septum
- Early evolution and recovery from excitotoxic injury in the neonatal rat brain: a study combining magnetic resonance imaging, electrical impedance, and histology
- Role of the excitotoxic mechanism in the development of neuronal damage following repeated brief cerebral ischemia in the gerbil: protective effects of MK-801 and …
- Immediate early gene activation during the initial phases of the excitotoxic cascade
- Transneuronal degeneration in substantia nigra pars reticulata following striatal excitotoxic injury in adult rat: time-course, distribution and morphology of cell death
- Thioltransferase (glutaredoxin) mediates recovery of motor neurons from excitotoxic mitochondrial injury
- excitotoxic hippocampal membrane breakdown and its inhibition by bilobalide: role of chloride fluxes
- excitotoxic lesions of the pedunculopontine differentially mediate morphine-and d-amphetamine-evoked striatal dopamine efflux and behaviors
- Seizures and selective CA-1 hippocampal lesions induced by an excitotoxic cyanide metabolite, 2-iminothiazolidine-4-carboxylic acid.
- Cerebral organic acid disorders induce neuronal damage via excitotoxic organic acids in vitro
- The cardiac glycoside ouabain potentiates excitotoxic injury of adult neurons in rat hippocampus
- Lack of excitotoxic cell death in serum-free cultures of rat cerebral cortex
- An examination of the effects of bilateral excitotoxic lesions of the pedunculopontine tegmental nucleus on responding to sucrose reward
- excitotoxic lesions of the pedunculopontine tegmental nucleus of the rat. I. Comparison of the effects of various excitotoxins, with particular reference to the loss of …
- Hippocampal neurons exhibit both persistent Ca2+ influx and impairment of Ca2+ sequestration/extrusion mechanisms following excitotoxic glutamate exposure
- 1‐Methyl‐4‐phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism
- Ectopic parvalbumin expression in mouse forebrain neurons increases excitotoxic injury provoked by ibotenic acid injection into the striatum
- Effects of neonatal excitotoxic lesions of the entorhinal cortex on cognitive functions in the adult rat
- The neuroprotective effects of the recombinant interleukin–1 receptor antagonist rhIL–1ra after excitotoxic stimulation with kainic acid and its relationship to the …
- Systemic application of granulocyte-colony stimulating factor and stem cell factor exacerbates excitotoxic brain injury in newborn mice
- excitotoxic lesions of the parafascicular nucleus produce deficits in a socially transmitted food preference
- Protective action of idebenone against excitotoxic degeneration in cultured cortical neurons
- Interactive effects of excitotoxic injury and dietary restriction on microgliosis and neurogenesis in the hippocampus of adult mice
- excitotoxic lesions of the mediodorsal thalamic nucleus attenuate intravenous cocaine self-administration
- excitotoxic injury induces monocyte chemoattractant protein-1 expression in neonatal rat brain
- Deficits in response initiation, but not attention, following excitotoxic lesions of posterior parietal cortex in the rat
- Biphasic NF-κB activation in the excitotoxic hippocampus
- Timing the excitotoxic induction of heat shock protein 70 transcription.
- Gene therapies that enhance hippocampal neuron survival after an excitotoxic insult are not equivalent in their ability to maintain synaptic transmission
- Ischemia does not induce the release of excitotoxic amino acids from the hippocampus of newborn rats
- Glutamate receptor transmission and ischemic nerve cell damage: evidence for involvement of excitotoxic mechanisms
- Two temporal stages of oligodendroglial response to excitotoxic lesion in the gray matter of the adult rat brain
- Susceptibility of striatal neurons to excitotoxic injury correlates with basal levels of Bcl-2 and the induction of P53 and c-Myc immunoreactivity
- A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N‐methyl‐d‐aspartate or quisqualate, and the effects on toxicity of 2 …
- excitotoxic basolateral amygdala lesions potentiate the memory impairment effect of muscimol injected into the medial septal area
- excitotoxic lesions of rat basal forebrain: differential effects on choline acetyltransferase in the cortex and amygdala
- Opposing effects of excitatory amino acids on chick embryo spinal cord motoneurons: excitotoxic degeneration or prevention of programmed cell death
- Are aminoglycoside antibiotics excitotoxic?
- Tat, a human immunodeficiency virus-1 derived protein, augments excitotoxic hippocampal injury in neonatal rats
- Proteasome inhibitors prevent cytochrome c release during apoptosis but not in excitotoxic death of cerebellar granule neurons
- Caspase-3-associated apoptotic cell death in excitotoxic necrosis of the entorhinal cortex following intraperitoneal injection of kainic acid in the rat
- In vivo role of caspases in excitotoxic neuronal death: generation and analysis of transgenic mice expressing baculoviral caspase inhibitor, p35, in postnatal neurons
- Inhibition of apoptosis‐inducing factor translocation is involved in protective effects of hepatocyte growth factor against excitotoxic cell death in cultured hippocampal …
- Cells over-expressing EAAT2 protect motoneurons from excitotoxic death in vitro
- Continuous physostigmine infusion in rats with excitotoxic lesions of the nucleus basalis magnocellularis: effects on performance in the water maze task and cortical …
- … and metabotropic glutamate receptors in the regulation of opioid mRNA expression and the onset of pain-related behavior following excitotoxic spinal cord injury
- Differential effects of prolonged high frequency stimulation and of excitotoxic lesion of the subthalamic nucleus on dopamine denervation‐induced cellular defects in …
- Dietary N-3 fatty acids inhibit ischaemic and excitotoxic brain damage in the rat
- Expression of inducible nitric oxide synthase and cyclooxygenase‐2 after excitotoxic damage to the immature rat brain
- β‐cyano‐L‐alanine toxicity: Evidence for the involvement of an excitotoxic mechanism
- Delayed death of septal cholinergic neurons after excitotoxic ablation of hippocampal neurons during early postnatal development in the rat
- Expression of growth inhibitory factor (metallothionein-III) mRNA and protein following excitotoxic immature brain injury
- Ciliary neurotrophic factor protects hippocampal neurons from excitotoxic damage
- Reversed actrocytic GLT-1 during ischemia is crucial to excitotoxic death of neurons, but contributes to the survival of astrocytes themselves
- Stat3 and NFκB glial expression after excitotoxic damage to the postnatal brain
- iNOS contribution to the NMDA-induced excitotoxic lesion in the rat striatum
- Intracellular glutathione levels determine cerebellar granule neuron sensitivity to excitotoxic injury by kainic acid
- Stability of septohippocampal neurons following excitotoxic lesions of the rat hippocampus
- Effects of excitotoxic lesions of the septum and vertical limb nucleus of the diagonal band of Broca on conditional visual discrimination: relationship between …
- Quisqualate‐induced excitotoxic death of glial cells: Transient vulnerability of cultured astrocytes
- Choline release and inhibition of phosphatidylcholine synthesis precede excitotoxic neuronal death but not neurotoxicity induced by serum deprivation
- Kainic acid-induced excitotoxic hippocampal neurodegeneration in C57BL/6 mice: B cell and T cell subsets may contribute differently to the pathogenesis
- Spinal and supraspinal changes in opioid mRNA expression are related to the onset of pain behaviors following excitotoxic spinal cord injury
- Effects of excitotoxic lesions of the substantia innominata, ventral and dorsal globus pallidus on visual discrimination acquisition, performance and reversal in the rat
- Effects of excitotoxic lesions of the rat prefrontal cortex on CREB regulation and presynaptic markers of dopamine and amino acid function in the nucleus accumbens
- Astroglial nitration after postnatal excitotoxic damage: correlation with nitric oxide sources, cytoskeletal, apoptotic and antioxidant proteins
- The neurotrophin receptors trkA, trkB and trkC are differentially regulated after excitotoxic lesion in rat striatum
- Recovery of song preferences after excitotoxic HVC lesion in female canaries
- Development of cholinergic amacrine cell stratification in the ferret retina and the effects of early excitotoxic ablation
- Association between inflammation and nigral neuronal damage following striatal excitotoxic lesion
- Behavioural sensitisation to repeated d-amphetamine: effects of excitotoxic lesions of the pedunculopontine tegmental nucleus
- Schedule-induced polydipsia and the nucleus accumbens: electrochemical measurements of dopamine efflux and effects of excitotoxic lesions in the core
- Selenium reduces the proapoptotic signaling associated to NF‐κB pathway and stimulates glutathione peroxidase activity during excitotoxic damage produced by …
- Cortical grafts prevent atrophy of cholinergic basal nucleus neurons induced by excitotoxic cortical damage
- NGF reduces striatal excitotoxic neuronal loss without affecting concurrent neuronal stress.
- excitotoxic lesions of the ventral anteroventral third ventricle and pressor responses to central sodium, ouabain and angiotensin II
- Short‐and long‐term survival of large neurons in the excitotoxic lesioned rat caudate nucleus: A light and electron microscopic study
- Cyclic GMP modulators and excitotoxic injury in cerebral cortical cultures
- Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat‐shock proteins and Bcl‐2
- Status of the neonatal rat brain after NMDA‐induced excitotoxic injury as measured by MRI, MRS and metabolic imaging
- Heme oxygenase‐1 activity after excitotoxic injury: Immunohistochemical localization of bilirubin in neurons and astrocytes and deleterious effects of heme oxygenase …
- excitotoxic lesions of the gustatory thalamus spare simultaneous contrast effects but eliminate anticipatory negative contrast: evidence against a memory deficit.
- Release of the excitotoxic amino acids, glutamate and aspartate, from the isolated ischemic/anoxic rat heart
- excitotoxic action of NMDA agonists on nigrostriatal dopaminergic neurons: modulation by inhibition of nitric oxide synthesis
- Local and downstream effects of excitotoxic lesions in the rat medial prefrontal cortex on in vivo 1H-MRS signals
- Susceptibility to excitotoxic and metabolic striatal neurodegeneration in the mouse is genotype dependent
- No effect of apolipoprotein E on neuronal cell death due to excitotoxic and apoptotic agents in vitro and neonatal hypoxic ischaemia in vivo
- On the probabilistic nature of excitotoxic neuronal death in hippocampal neurons
- Ontogeny of excitotoxic injury to nicotinamide adenine dinucleotide phosphate diaphorase reactive neurons in the neonatal rat striatum
- Enprofylline protects motor neurons from in vitro excitotoxic challenge
- Degeneration of neurons in the thalamic reticular nucleus following transient ischemia due to raised intracranial pressure: excitotoxic degeneration mediated via non …
- Varied actions of proinflammatory cytokines on excitotoxic cell death in the rat central nervous system
- Neuropeptide changes following excitotoxic lesion of the insular cortex in rats
- The effect of excitotoxic lesions of the pedunculopontine tegmental nucleus on performance of a progressive ratio schedule of reinforcement
- Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells
- Differential fos expression following aspiration, electrolytic, or excitotoxic lesions of the perirhinal cortex in rats.
- … MPEP and the Na+ channel blocker riluzole show different neuroprotective profiles in reversing behavioral deficits induced by excitotoxic prefrontal cortex lesions
- Grafting of fetal CA3 neurons to excitotoxic, axon-sparing lesions of the hippocampal CA3 area in adult rats
- Inorganic Pi Increases Neuronal Survival in the Acute Early Phase Following excitotoxic/Oxidative Insults
- Adenovirus-mediated over-expression of interleukin-1 receptor antagonist reduces susceptibility to excitotoxic brain injury in perinatal rats
- Effects of chronic lithium treatment on ornithine decarboxylase induction and excitotoxic neuropathology in the rat
- excitotoxic lesions of the paraventricular hypothalamus: metabolic and cardiac effects
- Conditioning heat stress reduces excitotoxic and apoptotic components of oxygen‐glucose deprivation‐induced neuronal death in vitro
- excitotoxic hippocampal neuron loss following sustained electrical stimulation of the perforant pathway in the mouse
- Nitric oxide applications prior and simultaneous to potentially excitotoxic NMDA-evoked calcium transients: Cell death or survival
- Two phases of behavioral plasticity in rats following unilateral excitotoxic lesion of the hippocampus
- Protection of excitotoxic neuronal death by gluconate through blockade of N-methyl-D-aspartate receptors
- The effects of excitotoxic hippocampal lesions in rats on risperidone-and olanzapine-induced locomotor suppression
- Prolonged infusion of quinolinic acid into rat striatum as an excitotoxic model of neurodegenerative disease
- Postnatal development of functional properties of visual cortical cells in rats with excitotoxic lesions of basal forebrain cholinergic neurons
- Evaluation of quinolinic acid induced excitotoxic neurodegeneration in rat striatum by quantitative magnetic resonance imaging in vivo
- Age dependent sensitivity of the rat retina to the excitotoxic action ofN-methyl-D-aspartate
- excitotoxic injury stimulates glial fibrillary acidic protein mRNA expression in perinatal rat brain
- Transcription of the Huntington disease gene during the quinolinic acid excitotoxic cascade
- The impact of excitotoxic blockade on the evolution of injury following combined mechanical and hypoxic insults in primary rat neuronal culture
- … -elicited immediate early gene expression in neurons and glia of the hippocampus: novel patterns of FOS, JUN, and KROX expression following excitotoxic injury
- Aminooxyacetic acid produces excitotoxic brain injury in neonatal rats
- A Tau antisense oligonucleotide decreases neurone sensitivity to excitotoxic injury.
- Ischemia as an excitotoxic lesion: protection against hippocampal nerve cell loss by denervation
- Behavioral evaluation of the anti-excitotoxic properties of MK-801: comparison with neurochemical measurements
- Mitogen and stress response kinase‐1 (MSK1) mediates excitotoxic induced death of hippocampal neurones
- … properties of competitive and uncompetitive N-methyl-D-aspartate receptor antagonists in vivo: implications for the process of excitotoxic degeneration and its therapy
- Non-spatial acquisition and retention deficits following small excitotoxic lesions within the hippocampus in monkeys
- Peptidyl α‐keto amide inhibitor of calpain blocks excitotoxic damage without affecting signal transduction events
- Differential DNA damage in response to the neonatal and adult excitotoxic hippocampal lesion in rats
- Effects of excitotoxic lesions of the nucleus basalis magnocellularis on conditioned taste aversion and inhibitory avoidance in the rat
- Effects of excitotoxic lesions of the gustatory thalamus on latent inhibition and blocking of conditioned taste aversion in rats
- Topical Insulin and Accumulation of excitotoxic and Other Amino Acids in Ischemic Rat Cerebral Cortex (44510)
- excitotoxic lesions of the lateral hypothalamus made by N-methyl-d-aspartate in the rat: behavioural, histological and biochemical analyses
- Fructose-1, 6-biphosphate prevents excitotoxic neuronal cell death in the neonatal mouse brain
- Glycine antagonist and NO synthase inhibitor protect the developing mouse brain against neonatal excitotoxic lesions
- excitotoxic damage of retinal glial cells depends upon normal neuron‐glial interactions
- Glucocorticoid treatment in an ischaemic-like excitotoxic model of periventricular leucomalacia in mice
- Retrograde degenerative changes in the substantia nigra pars compacta following an excitotoxic lesion of the striatum
- The effect of intravenous insulin on accumulation of excitotoxic and other amino acids in the ischemic rat cerebral cortex
- Striatopallidal neurons are selectively protected by neurturin in an excitotoxic model of Huntington’s disease
- 3-Nitropropionic acid produces indirect excitotoxic damage to rat striatum
- Behavioral effects of neonatal and adult excitotoxic lesions of the mediodorsal thalamus in the adult rat
- excitotoxic lesions of the entorhinal cortex leave gustatory within-event learning intact.
- Metabotropic glutamate receptor activation selectively limits excitotoxic damage in the intact neostriatum
- Enhanced locomotor activity in rats with excitotoxic lesions of the entorhinal cortex, a neurodevelopmental animal model of schizophrenia: behavioral and in vivo …
- Nitric oxide mediates the sustained opening of NMDA receptor-gated ionic channels which follows transient excitotoxic exposure in hippocampal slices
- Anti-porin antibodies prevent excitotoxic and ischemic damage to brain tissue
- Neurotrophic factor protection against excitotoxic neuronal death
- Thiokynurenates prevent excitotoxic neuronal death in vitro and in vivo by acting as glycine antagonists and as inhibitors of lipid peroxidation
- Apomorphine-induced dyskinesias after excitotoxic caudate-putamen lesions and the effects of neural transplantation in non-human primates
- Neonatal excitotoxic brain injury
- excitotoxic lesioning of the rat basal forebrain with S-AMPA: consequent mineralization and associated glial response
- GABA does not protect cerebro-cortical cultures against excitotoxic cell death
- Modulation of stress-induced dopamine release by excitotoxic damage of the entorhinal cortex in the rat
- Effect of nootropic Solcoseryl® on kainic acid-induced excitotoxic brain injury
- Bone marrow transplantation reveals roles for brain macrophage/microglia TNF signaling and nitric oxide production in excitotoxic neuronal death
- Increased proportion of high-affinity dopamine D2 receptors in rats with excitotoxic damage of the entorhinal cortex, an animal model of schizophrenia
- The calretinin‐containing mossy cells survive excitotoxic insult in the gerbil dentate gyrus. Comparison of excitotoxicity‐induced neuropathological changes in the …
- Changes in extracellular glutamate concentration after acute subdural haematoma in the rat—evidence for an “excitotoxic” mechanism?
- excitotoxic effect of kainic acid on chicken cochlear afferent neurons
- Long-lasting aberrant tubulovesicular membrane inclusions accumulate in developing motoneurons after a sublethal excitotoxic insult: a possible model for neuronal …
- A novel inhibitor of glutamate release reduces excitotoxic injury in vitro
- Role of tissue-derived plasminogen activator (t-PA) in an excitotoxic mouse model of neonatal white matter lesions
- Mineralization of the globus pallidus following excitotoxic lesions of the basal forebrain
- Protective effects of neurotrophin-4/5 and transforming growth factor-α on striatal neuronal phenotypic degeneration after excitotoxic lesioning with quinolinic acid
- In vivo microdialysis studies on the effects of decortication and excitotoxic lesions on kainic acid‐induced calcium fluxes, and endogenous amino acid release, in the …
- excitotoxic lesions of the pedunculopontine tegmental nucleus disinhibit orofacial behaviours stimulated by microinjections of d-amphetamine into rat ventrolateral …
- Competing approaches to excitotoxic neuroprotection by inert and catalytic antioxidant porphyrins
- excitotoxic lesions of the rhinal cortex in the baboon differentially affect visual recognition memory, habit memory and spatial executive functions
- excitotoxic Amino Acids Cause Appearance of Magnetic Resonance Spectroscopy‐Observable Zinc in Supervised Cortical Slices
- Adenoviral expression of CREB protects neurons from apoptotic and excitotoxic stress
- Cerebral metabolic consequences in the adult brain after neonatal excitotoxic lesions of the amygdala in rats
- Impairment of energy metabolism and excitotoxic cell death in Huntington disease.
- Administration of a non-NMDA antagonist, GYKI 52466, increases excitotoxic Purkinje cell degeneration caused by ibogaine
- Sustained, long-lasting inhibition of nitric oxide synthase aggravates the neural damage in some models of excitotoxic brain injury
- Topical glucose and accumulation of excitotoxic and other amino acids in ischemic cerebral cortex
- Dissociation between the excitatory and” excitotoxic” effects of quinolinic acid analogs on the striatal cholinergic interneuron.
- Learning impairments in monkeys with combined but not separate excitotoxic lesions of the anterior and mediodorsal thalamic nuclei
- excitotoxic neuronal death: mechanisms and clinical relevance
- Differential postreceptor signaling events triggered by excitotoxic stimulation of different ionotropic glutamate receptors in retinal neurons
- Evidence for synaptic proliferation, reorganization, and growth in the excitotoxic lesioned adult rat caudate nucleus
- Cortical changes in cholecystokinin mRNA are related to spontaneous pain behaviors following excitotoxic spinal cord injury in the rat
- Effect of perinatal alcohol exposure on ibotenic acid-induced excitotoxic cortical lesions in newborn hamsters
- 17β-Estradiol treatment retards excitotoxic delayed degeneration in substantia nigra reticulata neurons
- excitotoxic injury induces production of monocyte chemoattractant protein-1 in rat cortico-striatal slice cultures
- Comparison of the effects of the 5-HT 3 receptor antagonists WAY-100579 and ondansetron on spatial learning in the water maze in rats with excitotoxic lesions of the …
- excitotoxic increase of xanthine dehydrogenase and xanthine oxidase in the rat olfactory cortex
- Parallel development of excitotoxic vulnerability to N-methyl-l-aspartate and kainate in dispersed cultures of the rat cerebral cortex
- Anti-excitotoxic activity of trimetazidine in the retina
- MK-801 is cytotoxic to microglia in vitro and its cytotoxicity is attenuated by glutamate, other excitotoxic agents and atropine: Possible presence of glutamate receptor …
- Effect of excitotoxic lesions of the neonatal ventral hippocampus on the immobility response in rats
- excitotoxic lesions of the rostral thalamic reticular nucleus do not affect the performance of spatial learning and memory tasks in the rat
- Glial expression of the 90‐kDa heat shock protein (HSP90) and the 94‐kDa glucose‐regulated protein (GRP94) following an excitotoxic lesion in the mouse …
- Effect of acamprosate on neonatal excitotoxic cortical lesions in in utero alcohol-exposed hamsters
- Disparity of cell swelling and rapid neuronal death by excitotoxic insults in rat hippocampal slice cultures
- Dissociation of effects of glutamate receptor antagonists on excitotoxic and hypoxic neuronal cell death in a novel rat cortical culture system
- Expression of c-fos mRNA is increased and related to dynorphin mRNA expression following excitotoxic spinal cord injury in the rat
- excitotoxic injury profiles of low-affinity kainate receptor agonists in cortical neuronal cultures
- Myosin Va is proteolysed in rat cerebellar granule neurons after excitotoxic injury
- Bursting properties of units in cat globus pallidus and entopeduncular nucleus: the effect of excitotoxic striatal lesions
- excitotoxic lesions of the rat striatum: different responses of kynurenine pathway enzymes during ontogeny
- Synergistic effects of tetrahydroaminoacridine and lithium on cholinergic function after excitotoxic basal forebrain lesions in rat
- Extrasynaptic NMDA receptors: mediators of excitotoxic cell death
- PET studies of domoic acid poisoning in humans: excitotoxic destruction of brain glutamatergic pathways, revealed in measurements of glucose metabolism by …
- Effects of excitotoxic striatal lesions on single unit activity in globus pallidus and entopeduncular nucleus of the cat
- excitotoxic and anti-excitotoxic mechanisms in neurological disease
- Bioenergetics and excitotoxicity: the weak excitotoxic hypothesis
- Distribution of the messenger RNA for the extracellularly regulated kinases 1, 2 and 3 in rat brain: effects of excitotoxic hippocampal lesions
- Strychnine protection against excitotoxic cell death in primary cultures of rat cerebral cortex
- Cerebral cortical neuron apoptosis after mild excitotoxic injury in vitro: different roles of mesencephalic and cortical astrocytes
- excitotoxic amino acid receptors in human complex partial epilepsy
- excitotoxic lesions of the medial striatum delay extinction of a reinforcement color discrimination operant task in domestic chicks; a functional role of reward …
- Differential excitatory effects of kainic acid on CA3 and CA1 hippocampal pyramidal neurons: further evidence for the excitotoxic hypothesis and for a receptor …
- … of damage to the basal forebrain on brain glucose utilization: a reevaluation using positron emission tomography in baboons with extensive unilateral excitotoxic …
- Concomitant distribution shift of glial GABA transporter and S100 calcium-binding proteins in the rat retina after kainate-induced excitotoxic injury
- excitotoxic brain injury suppresses striatal high‐affinity glutamate uptake in perinatal rats
- Polymicrogyria: role of the excitotoxic damage
- Degeneration of hippocampal CA1 neurons following transient ischemia due to raised intracranial pressure: evidence for a temperature-dependent excitotoxic …
- Impaired volume regulation is the mechanism of excitotoxic sensitization to complement
- Mechanical and excitotoxic lesion of motoneurons: effects of neurotrophins and ciliary neurotrophic factor on survival and regeneration
- Is Purkinje cell loss in Leigh’s disease an excitotoxic event secondary to damage to inferior olivary nuclei?
- Attenuation of excitotoxic cell swelling and GABA release by the GABA transport inhibitor SKF 89976A
- Selectivity of excitotoxic mechanisms in Alzheimer’s disease
- excitotoxic striatal lesions protect against subsequent methamphetamine-induced dopamine depletions.
- excitotoxic profiles of novel, low-affinity kainate receptor agonists in primary cultures of murine cerebellar granule cells
- Effects of a new excitotoxic amino acid, dysiherbaine, on cultured Müller cells
- … alpha-methyl-p-tyrosine abolishes the enhancement of methamphetamine-induced extracellular dopamine levels in the amygdala of rats with excitotoxic lesions of the …
- The fatty acid composition of maternal diet affects the response to excitotoxic neural injury in neonatal rat pups
- excitotoxic lesions of the subthalamic nucleus ameliorate asymmetry induced by striatal dopamine depletion in the rat
- Quantitative histochemical measurement of GABA-transminase: Method for evaluation of intracerebral lesions produced by excitotoxic agents
- Differentially expressed genes in hippocampal cell cultures in response to an excitotoxic insult by quinolinic acid
- [24] excitotoxic amino acids as neuroendocrine research tools
- Site-specific actions of interleukin-1 on excitotoxic cell death in the rat striatum
- Electron spin resonance studies of the effects of naturally-occurring excitotoxic amino acid analogues on the physical state of membrane proteins in human …
- 3-Acetylpyridine produces age-dependent excitotoxic lesions in rat striatum
- Inhibition of excitotoxic neuronal cell death by total extracts from oriental medicines used for stroke treatment
- Mitochondrial impairment induces excitotoxic death in cerebellar granule cells
- Dissociation between the effects of interleukin-1 on excitotoxic brain damage and body temperature in the rat
- Impact of a preceding striatal excitotoxic lesion and treatment with ciliary neurotrophic factor on striatal graft survival
- Dextromethorphan analogs are neuroprotective in vitro and block glutamate-induced excitotoxic calcium signals in neurons
- Age-related vulnerability of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus
- A 24 h corticosterone exposure exacerbates excitotoxic insult in rat hippocampal slice cultures independently of glucocorticoid receptor activation or protein synthesis
- excitotoxic lesions of the prefrontal cortex attenuate the potentiation of amphetamine-induced locomotion by repeated neurotensin receptor activation
- Fos protein induction, neuropathology, and pharmacological protection after excitotoxic brain insult
- Ischemic and excitotoxic damage to brain slices from normal and microencephalic rats
- … ‐gated channels mediates the delayed, elevated increases in steady‐state c‐fos mRNA levels in cerebellar granule cells exposed to excitotoxic levels of glutamate
- Alteration of neuronal calcium homeostasis and excitotoxic vulnerability by chronic depolarization
- Preservation of cholinergic activity and prevention of neuron death by CEP-1347/KT-7515 following excitotoxic injury of the nucleus basalis magnocellularis
- Determination of acetylcholine and dopamine content in thalamus and striatum after excitotoxic lesions of the pedunculopontine tegmental nucleus in rats
- Distributed neurodegenerative changes 2–28 days after ventral hippocampal excitotoxic lesions in rats
- excitotoxic lesions of the prefrontal cortex reduce dopamine D1-like receptors in the ventral tegmental area
- Diltiazem protects human NT-2 neurons against excitotoxic damage in a model of simulated ischemia
- excitotoxic Brain Lesion Modifies Binding to a USF Binding Site Acting as a Negative Regulatory Element in theProtease Nexin-1Promoter
- Caffeine does not affect excitotoxic brain lesions in newborn mice
- excitotoxic effect of glutamate on the afferent neurons in guinea pigs
- Magnetic resonance spectroscopy studies on changes in cerebral calcium and zinc and the energy state caused by excitotoxic amino acids
- excitotoxic and apoptotic neuronal death induce different patterns of glial activation in vitro
- Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo
- An analysis of bioelectrical phenomena evoked by microiontophoretically applied excitotoxic amino-acids in the feline spinal cord
- Activation of the ornithine decarboxylase-polyamine system and induction of c-fos and p53 expression in relation to excitotoxic neuronal apoptosis in normal and …
- Extracellular putrescine content after acute excitotoxic brain damage in the rat
- excitotoxic amino acid neurotransmitters are increased in human cerebrospinal fluid after subarachnoid haemorrhage.
- Ontogenic study of the influence of tissue plasminogen activator (t-PA) in neonatal excitotoxic brain insult and the subsequent microglia/macrophage activation
- Ventricular dilatation over several weeks following induction of excitotoxic (systemic lithium/pilocarpine) lesions: potential role of damage to the substantia nigra …
- Expression of N‐methyl‐D‐aspartate receptors using vaccinia virus causes excitotoxic death in human kidney cells
- excitotoxic mechanisms of apoptosis in the mammalian visual system following monocular visual deprivation
- Effect of carnosine and its natural derivatives on apoptosis of neurons induced by excitotoxic compounds
- c-JUN, KROX-24, and c-FOS expression in hippocampal grafts placed in excitotoxic hippocampal lesions of the rat
- Taste Functions and Na+-Appetite After excitotoxic Lesions of the Parabrachial Nuclei in Rats
- Recombinant core protein fragment of phosphacan, a brain specific chondroitin sulfate proteoglycan, promote excitotoxic cell death of cultured rat hippocampal …
- Involvement of excitatory amino acid receptors in the mechanisms underlying excitotoxic phenomena
- excitotoxic cascade and neuroprotection in various stages of cerebral development
- Glial response to excitotoxic injury in the immature rat brain
- C-fos expression in the rat nucleus basalis upon excitotoxic lesion with quisqualic acid: a study in adult and aged animals
- Effects of excitotoxic median raphe lesion on working memory deficits produced by the dorsal hippocampal muscarinic receptor blockade in the inhibitory avoidance in …
- The pyrimidine derivative BW 1003C87 protects against excitotoxic lesions induced by kainate in the rat striatum
- excitotoxic mechanisms and neurological disease
- Nerve growth factor response to excitotoxic lesion of the cholinergic basal forebrain is slightly impaired in aged rats
- Crosstalk between calpain and calcineurin in excitotoxic neurodegeneration; Therapeutic targets for the treatment of excitotoxic neurodegeneration
- excitotoxic profile of LY339434, a GluR5 agonist, in cultured murine cortical neurons
- Morphological study on the excitotoxic effect of glutamate on rat hippocampus
- Impaired learning correlates with size of excitotoxic hippocampal CA3 lesions in adult rats, but shows no amelioration by CA3 transplants
- Decreased dendrite growth from cultured mouse cortical neurons surviving excitotoxic activation of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate/kainate …
- Morphological study on excitotoxic neurodegeneration of exogenous glutamate in newborn rat brain
- Inhibition of phosphatidylcholine synthesis is associated with excitotoxic cell death in cerebellar granule cell cultures
- Electrolytic lesions of the locus coeruleus or 6-hydroxydopamine lesions of the medial forebrain bundle protect against excitotoxic damage in rat hippocampus
- Heat-shock protein 72 expression in excitotoxic versus penetrating injuries of the rodent cerebral cortex
- excitotoxic neurodegeneration in Alzheimer disease
- Glutamate receptors and excitotoxic mechanisms in Alzheimer’s disease
- Ginkgolides protects the cultured rat cortical cells against metabolic, excitotoxic and oxidative insults
- Changes in the mitochondrial enzyme activity in striatal projection areas after unilateral excitotoxic striatal lesions: partial restoration by embryonic striatal transplants
- Decreased excitotoxic sensitivity in the olfactory cortex of adult rats after neonatal NMDA blockade.
- Olfactory bulbectomy protects hippocampal pyramidal neurons against excitotoxic death
- Fetal striatal transplants reinstate the electrophysiological response of pallidal neurons to systemic apomorphine challenge in rats with excitotoxic striatal lesions.
- excitotoxic lesions of histaminergic neurons by excitatory amino acid agonists in the rat brain
- … within primary cultures of mouse cerebellar granule cells stimulated with the excitatory amino acid L-glutamate: Correlation with excitotoxic outcome and derivation of …
- Absence of excitotoxic neuropathology in microencephalic rats after systemic kainic acid administration
- Glutamate-receptor elicited acetylcholinesterase release in mouse spinal cord slice: a model of early excitotoxic injury
- Transient potassium conductances protect nucleus tractus solitarius neurons from NMDA induced excitotoxic plateau depolarizations
- … neonatal blockade of NMDA receptor does not affect developmental polyamine metabolism but results in altered response to the excitotoxic induction of ornithine …
- Long-term cortical atrophy after excitotoxic striatal lesion: Effects of intrastriatal fetal-striatum grafts and implications for Huntington disease
- Effects of excitotoxic median raphe lesions on scopolamine-induced working memory deficits in inhibitory avoidance
- Constitutive nitric oxide synthase and ischemic/excitotoxic brain injury
- TH mRNA over-expression in rats with chronic excitotoxic striatal lesions.
- NGF treatment potentiates c-fos expression in the rat nucleus basalis upon excitotoxic lesion with quisqualic acid
- excitotoxic lesions of the neostriatum as an animal model of Huntington’s disease
- Changes in gene expression after transient ischemia as potential markers for excitotoxic pathology
- c-fos and tyrosine hydroxylase expression after an excitotoxic lesion on the nigrostriatal system: a study on the effects of hypoxia used as a preconditioning stimulus
- Chemokines and neonatal excitotoxic brain injury
- Knockout of p75 NTR does not alter the viability of striatal neurons following a metabolic or excitotoxic injury
- Facilitated extinction of appetitive instrumental conditioning following excitotoxic lesions of the core or the medial shell subregion of the nucleus accumbens in rats
- Blood-brain barrier permeability and stress; a study on excitotoxic stress and vasogenic edema
- … α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionate and N‐methyl‐d‐aspartate but not kainate receptors inhibits phosphatidylcholine synthesis before excitotoxic …
- Use of MRI to study excitotoxic spinal cord injury
- Effects and mechanisms of ginsenoside Rb3 on glutamate excitotoxic injury in cultured neurons of rat hippocampus
- Studies on excitotoxic damage in hippocampal neurons
- An excitotoxic Model of Alzheimer’s Disease: NMDA Lesions and Initial Neural Grafting Results
- Activation of NOS Interneurones in Striatum after excitotoxic Lesions of Rat Globus Pallidus
- Connective integration of hippocampal grafts in excitotoxic hippocampal lesions in adult rats: an anterograde axonal tracing study
- Effects of RU 52583, an α2-antagonist, on memory in rats with excitotoxic damage to the septal area
- Differential alterations of second messenger systems and cerebral glucose use following excitotoxic lesion of rat cerebral cortex
- Transplantation of developing hippocampal neurons to ischemic and excitotoxic lesions of the adult rat hippocampus
- excitotoxic lbnino Acids
- Induction of transcription factor A-myb expression in reactive astrocytes following an excitotoxic lesion in the mouse hippocampus
- Assessment of role of methyl cobalamine in excitotoxic effects of glutamicaid
- excitotoxic ablation.
- … desensitisation-preventing properties of a novel, subtype-selective AMPA receptor agonist,(S)-CPW 399, as a possible explanation for its excitotoxic action in cultured …
- Effects of excitotoxic lesions of the medial prefrontal cortex on density of high affinity [125I-Tyr3] neurotensin binding sites within the ventral midbrain and striatum
- excitotoxic lesions of the lateral parabrachial nucleus do not prevent cholecystokinin-induced suppression of milk intake in rats
- Chronic excitotoxic neurodegeneration induced by low dose of kainic acid administration intranasally in C57BL/6 mice
- Effects of excitotoxic lesions of the nucleus basalis magnocellularis on the acquisition of cocaine self-administration in the rat
- excitotoxic median raphe lesions aggravate working memory storage performance deficits caused by scopolamine infusion into the dentate gyrus of the …
- Cerebrospinal fluid flow in the excitotoxic model of posttraumatic syringomyelia
- An improved model for examining delayed excitotoxic neurodegeneration in isolated chick retina
- Neuroprotection of excitotoxic Brain Lesions in the Newborn Mouse by Glycine Antagonist and Inhibitor of No°. 159
- Spinal and supraspinal expression of PKC isoforms following excitotoxic spinal cord injury and implications for chronic pain management
- Methylation of the NMDA Receptor Agonistl-trans-2, 3-Pyrrolidine-Dicarboxylate: Enhanced excitotoxic Potency and Selectivity
- α‐Amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionic acid‐mediated excitotoxic axonal damage is attenuated in the absence of myelin proteolipid protein
- Anti-excitotoxic Therapies in Neurologic Diseases: Current Evidences and New Perspectives
- 25. Brain excitotoxic NetWorks in Heatstroke
- Anti-excitotoxic and Antioxidant TGF-BETA Family Neurotrophic Factors: In Vitro Screening Models of Motor Neuron Degeneration
- Drug discrimination learning in rats with excitotoxic lesions of nucleus basalis and ventral globus pallidus
- Barrier distruption following excitotoxic lesions in the brain of the anaesthetized rat
- excitotoxic and anti-excitotoxic effects of pyridine carboxylic acids and related compounds on various cholinergic brain nucleii.
- Studies on immediate early gene activation and excitotoxic neuronal death.
- The effect of pedunculopontine tegmental nucleus and lateral hypothalamic excitotoxic lesions on motivational strength as measured by the progressive ratio …
- Cerebellar neurones: Differentiation and modulation of sensitivity to excitotoxic treatment
- Progression of ischaemic stroke and excitotoxic aminoacids
- Effects of a New excitotoxic Amino Acid, Dysiherbaine, on Cultured Müller Cells
- Effects of a new excitotoxic amino acid, dysiherbaine, on cultured Müller cells
- On the role of mGluR1 in acute excitotoxic neuronal degeneration
- excitotoxic neuronal cell death in the adult rodent brain.
- excitotoxic mechanisms in Huntington’s disease
- Anti-excitotoxic Activity of Trimetazidine in the Retina
- Early evolution and recovery from excitotoxic injury in the neonatal rat brain
- excitotoxic Mechanisms in Adult Dissociated Mouse Retinal Cell Cultures
- Inhibition of Oxidative Stress-induced and excitotoxic Neuronal Cell Damage by Xuesaitong Ruanjiaonang
- Role of Nitric Oxide in excitotoxic and Ischemic Neuronal Damage
- excitotoxic neurodegeneration in mouse brain: Roles of immune cells and cytokines
- excitotoxic neurotoxicity in an in vitro brain slice model
- APOPTOSIS IN AN excitotoxic MODEL OF POST-TRAUMATIC SYRINGOMYELIA
- Interaction of excitotoxic and oxidative mechanisms in selective motor neuron injury: A hypothesis of ALS pathogenesis.
- 2-iminothiazolidine-4-carboxylic acid (2-ICA): An excitotoxic-independent hippocampal neurotoxin
- Modulation of the brain histaminergic system by excitotoxic lesions
- Early events following an excitotoxic insult in rat striatum
- Chemokines and Neonatal excitotoxic Brain Injury
- excitotoxic Cell Death in Cultured Retinal Neurons
- Factors Regulating excitotoxic Neurodegeneration: The Role of Calcium and the Mitochondria
- Neural regeneration and recovery in the cochlea after excitotoxic injury
- CHANGES IN NEURONS AND GLIA IN RESPONSE TO GLUTAMATERGIC excitotoxic EVENTS
- The role of calpain in excitotoxic neuronal cell death.
- Developmental Changes in excitotoxic Properties of Glutamate in Cultured Central Neurons† 257
- excitotoxic effects of glutamate on the in vitro spiral ganglion cells [J]
- excitotoxic Neurodegeneration by Vital Stains in Isolated Rat Retinas
- The time-course changes of astrocytes following an excitotoxic lesion in the CNS
- excitotoxic effects of glutamate on the in vitro spiral ganglion cells
- Activation of volume-sensitive Cl− channel in association with excitotoxic varicosity formation in cortical neurons
- Xenon Prevents a Long-Term excitotoxic Injury in Adult Rats
- Effect of excitotoxic lesions of rat medial prefrontal cortex on spatial memory
- Polyamines Exacerbate excitotoxic Death of Adult Retinal Ganglion Cells in vivo
- Effects of excitotoxic and immunotoxic lesions of the posterior parietal cortex on attention
- Pharmacological inhibition of NADPH oxidase does not reduce excitotoxic brain lesion in newborn mice
- Modulation of glutamate receptors in search of protection from excitotoxic-induced neuron death
- Mechanisms of dantrolene‐induced neuroprotection against excitotoxic injury
- excitotoxic change of Hippocampal Neuron by Kainic Acid in Rat Brain
- Functional changes in pyramidal neurons surviving an excitotoxic challenge in mouse organotypic slice cultures
- Glutamate Transporters: Molecular Mechanisms of Functional Alteration and Role in the Development of excitotoxic Neuronal Injury
- the excitotoxic cell death that is brought about by excess glutamate3. What have we learned from these findings and what remains enigmatic? We finally have a …
- Inhibitory Effects of Xiaoshuan Zaizao Wan on excitotoxic and Oxidative Neuronal Damage Induced in Primary Cultured Rat Cortical Cells
- Further evidence for the role of inositol trisphosphate as an excitotoxic death signal in hippocampal neurons
- Unusual Molecular Form of Cathepsin E Expressed at Early Stage of excitotoxic Damage in Hippocampal Neurons of Rats
- Effect of excitotoxic striatal lesions on the discharge pattern in globus pallidus and entopeduncular nucleus of the cat.
- The role of the AMPA receptor GluR2 subunit in anesthetic neurodepression and excitotoxic cell death
- Acute production of hydroxyl radicals does not participate in the excitotoxic effect of an intrastriatal perfusion of glutamate in rats
- excitotoxic damage of the hippocampus in the rat: involvement of N-methyl-D-aspartate receptors
- Neuroprotection against excitotoxic cell damage in rat striatum and hippocampus.
- Inhibition of a downstream effector of COX2 can attenuate excitotoxic brain injury
- Unsettled Role of Glutamate/Glutamate Receptors in Ischemic excitotoxic Neuronal Damage
- NMDA-evoked inhibition of phosphatidylcholine synthesis precedes excitotoxic neuronal death
- Glutamate receptor transmission and ischemic nerve cell damage: evidence for involvement of excitotoxic
- excitotoxic lesions of the rat nucleus basalis magnocellularis: implication of basoamygdaloid cholinergic projections in memory.
- INCREASED CSF-LEVELS OF excitotoxic AMINO-ACIDS AFTER FULL-TERM PERINATAL ASPHYXIA
- Stress-induced changes in sensitivity to thermal nociceptive stimulation in normal rats and following excitotoxic spinal cord injury
- Regulation of brain adenosine and adenine-nucleotide levels under excitotoxic conditions and in sleep regulation
- Ganglioside and Growth Factor Interactions Promote Mesencephalic Cell Survival from the excitotoxic Actions of 2, 4, 5-Trihydroxyphenylalanine
- … and dysfunctions of the nucleus basalis as Alzheimer’s disease models: general and critical overview and analysis of the long-term changes in several excitotoxic …
- Carbon monoxide (CO) protects against apoptosis caused by seizure‐related excitotoxic and inflammatory factors in the cerebral vasculature
- Inhibition of Tissue Plasminogen Activator Attenuates Non–NMDA Receptor–Mediated excitotoxic Retinal Degeneration
- IMPAIRED COGNITIVE PERFORMANCE AFTER NEONATAL excitotoxic HIPPOCAMPAL DAMAGE IN RATS: FURTHER EVALUATION OF AN ANIMAL MODEL …
- excitotoxic lesions of the hippocampus leave sensory preconditioning intact: Implications for models of hippocampal functioning
- Comparison between aspirative versus excitotoxic lesions of the lateral entorhinal cortex on conditioned odor aversionin the rat
- Fentanyl, but Not Sufentanil, Exacerbates Neonatal excitotoxic White Matter Lesions Via the ORL-1 Receptor
- EFFECTS OF excitotoxic LESIONS OF THE NUCLEUS BASALIS MAGNOCELLULARIS ON LOCOMOTOR RESPONSES TO CONDITIONED AND …
- Detection of Single and Double Strand DNA Breaks during excitotoxic or Apoptotic Neuronal Cell Death
- Region-specific expression of the interleukin-1 system in rat brain following endotoxin challenge and excitotoxic neurodegeneration
- Potential neuroprotective characteristics of cannabinoids on excitotoxic neurodegeneration in the spastic Han-Wistar rat
- Anti-excitotoxic and Antioxidant TGF-BETA Family Neurotropic Factors: In Vitro Screening Models of Motor Neuron Degeneration
- S. Marty, I. Dusart and M. Peschanski.“Glial Changes Following an excitotoxic Lesion in the CNS–I. Microglia/Macrophages.” Neuroscience. vol. 45, No. 3,(1991 …
- EFFECTS OF excitotoxic LESIONS OF THE CA1 FIELD IN MARMOSET HIPPOCAMPUS AS A MODEL OF HUMAN AMNESIA
- Imaging of spreading depression under low oxygen/glucose and excitotoxic conditions in the mouse hemi-brain slice.
- Wogonin protects neuronal cells from excitotoxic and oxidative injuries in primary cultured rat cortical cells
- Neuroprotective effects of overexpression of the inhibitor of apoptosis proteins in the quinolinic acid model of excitotoxic injury.
- The effects of GDNF against kainic acid excitotoxic injury on neonatal rat doral root ganglion neurons in vitro
- Chronic in utero ischemia protects newborn mice against excitotoxic periventricular white matter cysts• 1122
- Wogonin protects neuronal cells from excitotoxic and oxidative injuries in primary cultured rat cortical cells
- Changes in Basal Forebrain Cholinergic Systems Following excitotoxic Cell Death in the Hippocampus and Cerebral Neocortex
- The role of group I metabotropic glutamate receptors in excitotoxic cell death induced by exposure to ionotropic agonist kainic acid
- Regulation of CNTF and CNTF receptor phosphorylation after excitotoxic lesion in neuron/astrocyte co-culture
- excitotoxic damage to brain tissue subsequent to a graft-induced excess of neurotransmitter substance in some brain areas remains an important subject that …
- Cytological alterations in nrm neurons in male rats following formalin induced pain and excitotoxic lesion of vl pag-nrm pathway by ibotenic acid
- The human NT-2 cell line as in vitro model system for the excitotoxic cascade during stroke
- Effects of excitotoxic thalamic lesion upon 14C-2-deoxyglucose (DG) uptake in the somatosensory cortex of the adult mouse
- Effect of Mediodorsal Thalamus and Ventral Hippocampus excitotoxic Lesion in the Adult Rat: Implicate the Neuropathology of Schizophrenia
- SELF-ORDERED SPATIAL SEARCHING IN PRIMATES: CONTRASTING EFFECTS OF excitotoxic LESIONS AND DOPAMINE DEPLETION OF THE …
- Sites and mechanisms of IL-1 action in ischemic and excitotoxic brain damage
- POSTERS: Localised changes in expression of calcium binding proteins induced by chronic application of an excitotoxic agent, β-N-oxalyl-L-α, β diaminopropionic …
- (647): Effects of acute stress on nociceptive responses following excitotoxic spinal injury: A model of stress induced hyperalgesia
- … COMMUNICATIONFetal striatal transplants reinstate the electrophysiological response of pallidal neurons to systemic apomorphine challenge in rats with excitotoxic …
- 347 Cannabinoids Protect Against excitotoxic Brain Lesions in Newborn Mice
- 318 Maternal LPS Enhances excitotoxic Brain Lesions in Newborn Rats
- … , nitric oxide; nNOS, neuronal NOS; NOS, NO synthase; ONOO−, peroxynitrite; PBD, PSD95-binding domain. a target for inhibition of excitotoxic p38 stress-activated …
- 325 Effect of Triiodothyronine (T3) on excitotoxic Brain Damage of Newborn Mice
- Distribution of betaine/gaba transporter BGT-1 in excitotoxic brain injury and its role in osmoregulation in the brain
- Protective Effects of Neurotrophin-3 on The excitotoxic Damage of Cochlear Afferent Neurons in Guinea Pigs
- Current Problems in Epilepsy, vol. 8: Epileptogenic and excitotoxic Mechanisms
- THE ADENOSINE A2A RECEPTOR ANTAGONIST ZM 241385 DIFFERENTIALLY INFLUENCES excitotoxic MECHANISMS AT PRE AND POST-SYNAPTIC SITE …
- 17 excitotoxic and oxidative cross-talk between motor neurons and glia in ALS pathogenesis
- A study of neuronal calcium (2+) homeostasis: Application to the pathophysiology and treatment of early excitotoxic and hypoxic/ischemic neuronal injury in vitro and …
- excitotoxic mechanisms in stroke: an update of concepts and treatment strategies
- excitotoxic damage to white matter
- Molecular and cellular mechanisms of excitotoxic neuronal death
- NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo
- excitotoxic neuronal death and the pathogenesis of Huntington’s disease
- The subtype of GluN2 C-terminal domain determines the response to excitotoxic insults
- Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain
- excitotoxic death of retinal neurons in vivo occurs via a non-cell-autonomous mechanism
- An overview of brain-derived neurotrophic factor and implications for excitotoxic vulnerability in the hippocampus
- Targeting excitotoxic/free radical signaling pathways for therapeutic intervention in glaucoma
- Tau exacerbates excitotoxic brain damage in an animal model of stroke
- Involvement of autophagy in hypoxic-excitotoxic neuronal death
- The role of excitotoxic programmed necrosis in acute brain injury
- Synaptic NMDA receptors mediate hypoxic excitotoxic death
- Calpains are downstream effectors of bax-dependent excitotoxic apoptosis
- excitotoxic mechanisms of ischemic injury in myelinated white matter
- excitotoxic neuroprotection and vulnerability with CaMKII inhibition
- NP031112, a thiadiazolidinone compound, prevents inflammation and neurodegeneration under excitotoxic conditions: potential therapeutic role in brain disorders
- Context-but not familiarity-dependent forms of object recognition are impaired following excitotoxic hippocampal lesions in rats.
- Tumor necrosis factor is elevated in progressive multiple sclerosis and causes excitotoxic neurodegeneration
- Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture
- Intracellular zinc is a critical intermediate in the excitotoxic cascade
- Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis
- Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death
- Role of NMDA receptor–dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries
- Pilocarpine-induced status epilepticus in rats involves ischemic and excitotoxic mechanisms
- Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease
- Roles of prostaglandin synthesis in excitotoxic brain diseases
- Ex vivo and in vivo neuroprotection induced by argon when given after an excitotoxic or ischemic insult
- Fingolimod protects cultured cortical neurons against excitotoxic death
- excitotoxic potential of the cyanotoxin β-methyl-amino-L-alanine (BMAA) in primary human neurons
- Roles of volume-sensitive chloride channel in excitotoxic neuronal injury
- Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic neuronal injuries
- Striatal astrocytes produce neuroblasts in an excitotoxic model of Huntington’s disease
- Dysregulation of tau phosphorylation in mouse brain during excitotoxic damage
- Increased levels of proinflammatory cytokines in the aged rat brain attenuate injury‐induced cytokine response after excitotoxic damage
- Neuroprotection by co-treatment and post-treating with calcitriol following the ischemic and excitotoxic insult in vivo and in vitro
- Rho mediates calcium-dependent activation of p38α and subsequent excitotoxic cell death
- Glucocorticoids increase excitotoxic injury and inflammation in the hippocampus of adult male rats
- Dexamethasone-induced acute excitotoxic cell death in the developing brain
- excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of l‐carnitine
- A β-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis
- excitotoxic glutamate insults block autophagic flux in hippocampal neurons
- A fluorescence vital assay for the recognition and quantification of excitotoxic cell death by necrosis and apoptosis using confocal microscopy on neurons in culture
- TNF receptor I sensitizes neurons to erythropoietin-and VEGF-mediated neuroprotection after ischemic and excitotoxic injury
- NMDA receptor modulation by the neuropeptide apelin: implications for excitotoxic injury
- CCL11 enhances excitotoxic neuronal death by producing reactive oxygen species in microglia
- Apelin, an endogenous neuronal peptide, protects hippocampal neurons against excitotoxic injury
- excitotoxic lesions in the central nucleus of the amygdala attenuate stress-induced anxiety behavior
- Increased vesicular glutamate transporter expression causes excitotoxic neurodegeneration
- Monosodium glutamate neonatal treatment as a seizure and excitotoxic model
- Nanomolar concentrations of anabolic–androgenic steroids amplify excitotoxic neuronal death in mixed mouse cortical cultures
- Faster perceptual learning through excitotoxic neurodegeneration
- The mouse brain metabolome: region-specific signatures and response to excitotoxic neuronal injury
- Intracellular pH reduction prevents excitotoxic and ischemic neuronal death by inhibiting NADPH oxidase
- excitotoxic lesions restricted to the dorsal CA1 field of the hippocampus impair spatial memory and extinction learning in C57BL/6 mice
- excitotoxic stimulus stabilizes PFKFB3 causing pentose-phosphate pathway to glycolysis switch and neurodegeneration
- Neuroinflammation is associated with changes in glial mGluR5 expression and the development of neonatal excitotoxic lesions
- Novel positive allosteric modulators of glutamate transport have neuroprotective properties in an in vitro excitotoxic model
- Interleukin-1β causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53
- Quercetin, kaempferol and biapigenin from Hypericum perforatum are neuroprotective against excitotoxic insults
- Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice
- excitotoxic brain injury in adult zebrafish stimulates neurogenesis and long‐distance neuronal integration
- Protective effect of Calendula officinalis L. flowers against monosodium glutamate induced oxidative stress and excitotoxic brain damage in rats
- BACE1 mediates HIV-associated and excitotoxic neuronal damage through an APP-dependent mechanism
- Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate
- excitotoxic loss of post‐synaptic sites is distinct temporally and mechanistically from neuronal death
- Norrin protects retinal ganglion cells from excitotoxic damage via the induction of leukemia inhibitory factor
- Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X7 receptor‐mediated IL‐1β release
- The excitotoxic effect of NMDA on human lymphocyte immune function
- Ca2+-permeable AMPARs mediate glutamatergic transmission and excitotoxic damage at the hair cell ribbon synapse
- Na+, K+-ATPase functionally interacts with the plasma membrane Na+, Ca2+ exchanger to prevent Ca2+ overload and neuronal apoptosis in excitotoxic stress
- Enhanced autophagy contributes to excitotoxic lesions in a rat model of preterm brain injury
- Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice
- Lithium prevents excitotoxic cell death of motoneurons in organotypic slice cultures of spinal cord
- Quantitative proteomic analyses of dynamic signalling events in cortical neurons undergoing excitotoxic cell death
- p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autophagic mechanisms
- Protection of cochlear synapses from noise-induced excitotoxic trauma by blockade of Ca2+-permeable AMPA receptors
- The redox biology of excitotoxic processes: the NMDA receptor, TOPA quinone, and the oxidative liberation of intracellular zinc
- The effects of glycemic control on seizures and seizure-induced excitotoxic cell death
- Role of CCR5 and its ligands in the control of vascular inflammation and leukocyte recruitment required for acute excitotoxic seizure induction and neural damage
- Stimulation of prostaglandin E2-EP3 receptors exacerbates stroke and excitotoxic injury
- Vascular endothelial growth factor prevents paralysis and motoneuron death in a rat model of excitotoxic spinal cord neurodegeneration
- Expression of osteopontin in the rat retina: effects of excitotoxic and ischemic injuries
- ACTH protects mature oligodendroglia from excitotoxic and inflammation‐related damage in vitro
- Assessment of intrinsic and extrinsic signaling pathway in excitotoxic retinal ganglion cell death
- A beacon of hope in stroke therapy—Blockade of pathologically activated cellular events in excitotoxic neuronal death as potential neuroprotective strategies
- α-MSH rescues neurons from excitotoxic cell death
- Cofilin activation mediates Bax translocation to mitochondria during excitotoxic neuronal death
- Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo
- Bax and calpain mediate excitotoxic oligodendrocyte death induced by activation of both AMPA and kainate receptors
- Kidins220/ARMS downregulation by excitotoxic activation of NMDARs reveals its involvement in neuronal survival and death pathways
- Longitudinal characterization of cognitive and motor deficits in an excitotoxic lesion model of striatal dysfunction in non-human primates
- Wallerian-like axonal degeneration in the optic nerve after excitotoxic retinal insult: an ultrastructural study
- CCAAT/enhancer binding protein β deficiency provides cerebral protection following excitotoxic injury
- Tat-NR2B9c prevents excitotoxic neuronal superoxide production
- Protective effect of spermidine against excitotoxic neuronal death induced by quinolinic acid in rats: possible neurotransmitters and neuroinflammatory mechanism
- Selective dendritic susceptibility to bioenergetic, excitotoxic and redox perturbations in cortical neurons
- Laquinimod ameliorates excitotoxic damage by regulating glutamate re-uptake
- excitotoxic superoxide production and neuronal death require both ionotropic and non-ionotropic NMDA receptor signaling
- Diazepam neuroprotection in excitotoxic and oxidative stress involves a mitochondrial mechanism additional to the GABAAR and hypothermic effects
- VEGFD protects retinal ganglion cells and, consequently, capillaries against excitotoxic injury
- Identification of novel pharmacological targets to minimize excitotoxic retinal damage
- Melatonin reduces excitotoxic blood–brain barrier breakdown in neonatal rats
- An organotellurium compound with antioxidant activity against excitotoxic agents without neurotoxic effects in brain of rats
- Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology
- A new transgenic mouse model for studying the neurotoxicity of spermine oxidase dosage in the response to excitotoxic injury
- The specific PKR inhibitor C16 prevents apoptosis and IL-1β production in an acute excitotoxic rat model with a neuroinflammatory component
- c‐Jun N‐terminal kinase signaling pathway in excitotoxic cell death following kainic acid‐induced status epilepticus
- A cannabinoid receptor-mediated mechanism participates in the neuroprotective effects of oleamide against excitotoxic damage in rat brain synaptosomes and cortical …
- Different pathways lead to mitochondrial fragmentation during apoptotic and excitotoxic cell death in primary neurons
- Sustained NMDA receptor activation by spreading depolarizations can initiate excitotoxic injury in metabolically compromised neurons
- Anti-excitotoxic effects of cannabidiol are partly mediated by enhancement of NCX2 and NCX3 expression in animal model of cerebral ischemia
- Neuroprotective effects of hydroxysafflor yellow A against excitotoxic neuronal death partially through down-regulation of NR2B-containing NMDA receptors
- Allosteric modulation of AMPA receptors counteracts Tau-related excitotoxic synaptic signaling and memory deficits in stress-and Aβ-evoked hippocampal pathology
- Copaiba oil-resin treatment is neuroprotective and reduces neutrophil recruitment and microglia activation after motor cortex excitotoxic injury
- NR2A and NR2B subunits differentially mediate MAP kinase signaling and mitochondrial morphology following excitotoxic insult
- The fate of “dark” neurons produced by transient focal cerebral ischemia in a non-necrotic and non-excitotoxic environment: neurobiological aspects
- Cleavage of the vesicular GABA transporter under excitotoxic conditions is followed by accumulation of the truncated transporter in nonsynaptic sites
- Hydroxysafflor yellow A protects neurons from excitotoxic death through inhibition of NMDARs
- Trasmembrane chemokines CX3CL1 and CXCL16 drive interplay between neurons, microglia and astrocytes to counteract pMCAO and excitotoxic neuronal …
- excitotoxic glutamate causes neuronal insulin resistance by inhibiting insulin receptor/Akt/mTOR pathway
- Neuroprotective effect of inhaled nitric oxide on excitotoxic-induced brain damage in neonatal rat
- Procyanidin B2 protects neurons from oxidative, nitrosative, and excitotoxic stress
- Hippocampus glutamate and N-acetyl aspartate markers of excitotoxic neuronal compromise in posttraumatic stress disorder
- A role for polyamines in retinal ganglion cell excitotoxic death
- excitotoxic stimulation downregulates the ubiquitin–proteasome system through activation of NMDA receptors in cultured hippocampal neurons
- Vulnerability of hippocampal GABA‐ergic interneurons to kainate‐induced excitotoxic injury during old age
- … nicotinic acetylcholine receptors can be overcome by positive allosteric modulation and serum factors leading to the generation of excitotoxic currents at physiological …
- Beneficial effects of remifentanil against excitotoxic brain damage in newborn mice
- Neuroprotection by glutamate receptor antagonists against seizure-induced excitotoxic cell death in the aging brain
- Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: possible involvement of the endocannabinoid and endovanilloid systems
- Reduced axonal transport and increased excitotoxic retinal ganglion cell degeneration in mice transgenic for human mutant P301S tau
- TNF-α triggers rapid membrane insertion of Ca2+ permeable AMPA receptors into adult motor neurons and enhances their susceptibility to slow excitotoxic injury
- The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for GRIA2 mRNA processing
- Persistent cognitive deficits, induced by intrathecal methotrexate, are associated with elevated CSF concentrations of excitotoxic glutamate analogs and can be …
- Phosphoinositide 3-kinase couples NMDA receptors to superoxide release in excitotoxic neuronal death
- Cellular interplay between neurons and glia: toward a comprehensive mechanism for excitotoxic neuronal loss in neurodegeneration
- G protein–coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation‐induced sensitization to excitotoxic neurodegeneration
- Childhood status epilepticus and excitotoxic neuronal injury
- S-Allylcysteine protects against excitotoxic damage in rat cortical slices via reduction of oxidative damage, activation of Nrf2/ARE binding, and BDNF preservation
- Functional role of neurotrophin-3 in synapse regeneration by spiral ganglion neurons on inner hair cells after excitotoxic trauma in vitro
- Matrine regulates glutamate-related excitotoxic factors in experimental autoimmune encephalomyelitis
- NMDA receptor‐mediated excitotoxic neuronal apoptosis in vitro and in vivo occurs in an ER stress and PUMA independent manner
- Antenatal bacterial endotoxin sensitizes the immature rat brain to postnatal excitotoxic injury
- Xenon-mediated neuroprotection in response to sustained, low-level excitotoxic stress
- The GluK4 kainate receptor subunit regulates memory, mood, and excitotoxic neurodegeneration
- Reactivity of microglia and astrocytes after an excitotoxic injury induced by kainic acid in the rat spinal cord
- Bok is not pro-apoptotic but suppresses poly ADP-ribose polymerase-dependent cell death pathways and protects against excitotoxic and seizure-induced neuronal …
- Response of transcription factor NFATc3 to excitotoxic and traumatic brain insults: identification of a subpopulation of reactive astrocytes
- Zeta inhibitory peptide, a candidate inhibitor of protein kinase Mζ, is excitotoxic to cultured hippocampal neurons
- Otx2 promotes the survival of damaged adult retinal ganglion cells and protects against excitotoxic loss of visual acuity in vivo
- Modulation of extrasynaptic GABAergic receptor activity influences glutamate release and neuronal survival following excitotoxic damage to mouse spinal cord …
- Cytosolic zinc accumulation contributes to excitotoxic oligodendroglial death
- Identification of synaptotagmin 10 as effector of NPAS4-mediated protection from excitotoxic neurodegeneration
- Genetic inhibition of caspase‐2 reduces hypoxic‐ischemic and excitotoxic neonatal brain injury
- A Neurotoxic Ménage-à-trois: Glutamate, Calcium, and Zinc in the excitotoxic Cascade
- Permissive role for mGlu1 metabotropic glutamate receptors in excitotoxic retinal degeneration
- Role of cyclophilin D-dependent mitochondrial permeability transition in glutamate-induced calcium deregulation and excitotoxic neuronal death
- Role of HSP70 in motoneuron survival after excitotoxic stress in a rat spinal cord injury model in vitro
- Stereotaxic surgery for excitotoxic lesion of specific brain areas in the adult rat
- Expression of CD200 in alternative activation of microglia following an excitotoxic lesion in the mouse hippocampus
- Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia
- Correlation between afferent rearrangements and behavioral deficits after local excitotoxic insult in the mammalian vestibule: a rat model of vertigo symptoms
- Endogenous Wnt/β-catenin signaling in Müller cells protects retinal ganglion cells from excitotoxic damage
- Nicotinamide mononucleotide adenylyl transferase 1 protects against acute neurodegeneration in developing CNS by inhibiting excitotoxic-necrotic cell death
- PACAP improves functional outcome in excitotoxic retinal lesion: an electroretinographic study
- A functional dissociation of the anterior and posterior pedunculopontine tegmental nucleus: excitotoxic lesions have differential effects on locomotion and the …
- Ondansetron reduces lasting vestibular deficits in a model of severe peripheral excitotoxic injury
- Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3–phosphatidylinositol 3-kinase–akt pathway through its sex hormone-binding …
- excitotoxic targeting of Kidins220 to the Golgi apparatus precedes calpain cleavage of Rap1-activation complexes
- JNK1 inhibition by Licochalcone A leads to neuronal protection against excitotoxic insults derived of kainic acid
- Presynaptic silencing is an endogenous neuroprotectant during excitotoxic insults
- Flavor and object recognition memory impairment induced by excitotoxic lesions of the perirhinal cortex
- Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism
- iNOS-derived NO and nox2-derived superoxide confer tolerance to excitotoxic brain injury through peroxynitrite
- Ceftriaxone preserves glutamate transporters and prevents intermittent hypoxia-induced vulnerability to brain excitotoxic injury
- The inflammatory cytokine, interleukin‐1 beta, mediates loss of astroglial glutamate transport and drives excitotoxic motor neuron injury in the spinal cord during acute …
- Calpain activation and Na+/Ca2+ exchanger degradation occur downstream of calcium deregulation in hippocampal neurons exposed to excitotoxic glutamate
- Possible prophylactic anti-excitotoxic and anti-oxidant effects of virgin coconut oil on aluminium chloride-induced Alzheimer’s in rat models
- Exposure of neurons to excitotoxic levels of glutamate induces cleavage of the RNA editing enzyme, adenosine deaminase acting on RNA 2, and loss of GLUR2 …
- excitotoxic and radiation stress increase TERT levels in the mitochondria and cytosol of cerebellar Purkinje neurons
- The pharmacological inhibition of fatty acid amide hydrolase prevents excitotoxic damage in the rat striatum: possible involvement of CB1 receptors regulation
- Olfactory training prevents olfactory dysfunction induced by bulbar excitotoxic lesions: role of neurogenesis and dopaminergic interneurons
- Protective effects of 7, 8-dihydroxyflavone on retinal ganglion and RGC-5 cells against excitotoxic and oxidative stress
- HIP/PAP prevents excitotoxic neuronal death and promotes plasticity
- In vivo evaluation of white matter integrity and anterograde transport in visual system after excitotoxic retinal injury with multimodal MRI and OCT
- TRPing into excitotoxic neuronal death
- Excitatory neurosteroids attenuate apoptotic and excitotoxic cell death in primary cortical neurons
- Absence of aryl hydrocarbon receptors increases endogenous kynurenic acid levels and protects mouse brain against excitotoxic insult and oxidative stress
- Neuroprotection by GH against excitotoxic-induced cell death in retinal ganglion cells
- Contribution of endogenous glycine and d-serine to excitotoxic and ischemic cell death in rat cerebrocortical slice cultures
- Glial response to 17β-estradiol in neonatal rats with excitotoxic brain injury
- Differential effects of serotonin-specific and excitotoxic lesions of OFC on conditioned reinforcer devaluation and extinction in rats
- Delayed neuroprotection by riluzole against excitotoxic damage evoked by kainate on rat organotypic spinal cord cultures
- excitotoxic lesions of the infralimbic, but not prelimbic cortex facilitate reversal of appetitive discriminative context conditioning: the role of the infralimbic cortex …
- Combined excitotoxic–oxidative stress and the concept of non-cell autonomous pathology of ALS: Insights into motoneuron axonopathy and astrogliosis
- ASIC channel inhibition enhances excitotoxic neuronal death in an in vitro model of spinal cord injury
- Minocycline treatment reduces white matter damage after excitotoxic striatal injury
- Treatment with the ketone body D-β-hydroxybutyrate attenuates autophagy activated by NMDA and reduces excitotoxic neuronal damage in the rat striatum in vivo
- Mild in vitro trauma induces rapid Glur2 endocytosis, robustly augments calcium permeability and enhances susceptibility to secondary excitotoxic insult in cultured …
- VEGF protects spinal motor neurons against chronic excitotoxic degeneration in vivo by activation of PI3‐K pathway and inhibition of p38MAPK
- Mutant LRRK2 enhances glutamatergic synapse activity and evokes excitotoxic dendrite degeneration
- Blood glutamate grabbing does not reduce the hematoma in an intracerebral hemorrhage model but it is a safe excitotoxic treatment modality
- excitotoxic neurodegeneration is associated with a focal decrease in metabotropic glutamate receptor type 5 availability: an in vivo PET imaging study
- Interactive effect of excitotoxic injury and dietary restriction on neurogenesis and neurotrophic factors in adult male rat brain
- Interleukin-10 and Interleukin refeceptor-I Are Upregulated in Glial Cells After an excitotoxic Injury to the Postnatal Rat Brain
- Oxidative and excitotoxic insults exert differential effects on spinal motoneurons and astrocytic glutamate transporters: Implications for the role of astrogliosis in …
- Sequential expression of cell‐cycle regulators and Alzheimer’s disease–related proteins in entorhinal cortex after hippocampal excitotoxic damage
- Recovery of olfactory function after excitotoxic lesion of the olfactory bulbs is associated with increases in bulbar SIRT1 and SIRT4 expressions
- Effects of neuron-specific ADAM10 modulation in an in vivo model of acute excitotoxic stress
- Adenine nucleotide translocator 1 deficiency increases resistance of mouse brain and neurons to excitotoxic insults
- The C‐terminal domain of tetanus toxin protects motoneurons against acute excitotoxic damage on spinal cord organotypic cultures
- Neural crest stem cells protect spinal cord neurons from excitotoxic damage and inhibit glial activation by secretion of brain-derived neurotrophic factor
- Neuroprotective effects of the sigma-1 receptor ligand PRE-084 against excitotoxic perinatal brain injury in newborn mice
- Delayed Administration of VEGF Rescues Spinal Motor Neurons from Death with a Short Effective Time Frame in excitotoxic Experimental Models in Vivo
- Intracellular Zn2+ increases contribute to the progression of excitotoxic Ca2+ increases in apical dendrites of CA1 pyramidal neurons
- S100β as an early biomarker of excitotoxic damage in spinal cord organotypic cultures
- N‐Methyl‐d‐aspartate receptor subunit‐ and neuronal‐type dependence of excitotoxic signaling through post‐synaptic density 95
- Neuroprotective effects of NAP against excitotoxic brain damage in the newborn mice: implications for cerebral palsy
- Neuroprotective effects of a protein tyrosine phosphatase inhibitor against hippocampal excitotoxic injury
- Inhibition of the adenosine A2A receptor mitigates excitotoxic injury in organotypic tissue cultures of the rat cochlea
- Cleavage of the vesicular glutamate transporters under excitotoxic conditions
- Cyclooxygenase-2 mediates the sensitizing effects of systemic IL-1-beta on excitotoxic brain lesions in newborn mice
- Olfactory function in an excitotoxic model for secondary neuronal degeneration: role of dopaminergic interneurons
- Implanted neurosphere-derived precursors promote recovery after neonatal excitotoxic brain injury
- Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins
- Subarachnoid transplant of a human neuronal cell line attenuates chronic allodynia and hyperalgesia after excitotoxic spinal cord injury in the rat
- Generating excitotoxic lesion models of Huntington’s disease
- excitotoxic lesions of the superior colliculus preferentially impact multisensory neurons and multisensory integration
- Neuroprotection of Ilex latifolia and caffeoylquinic acid derivatives against excitotoxic and hypoxic damage of cultured rat cortical neurons
- Sphingosine 1‐phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes
- Drug screening of neuroprotective agents on an organotypic-based model of spinal cord excitotoxic damage
- Caspase‐3 activation in astrocytes following postnatal excitotoxic damage correlates with cytoskeletal remodeling but not with cell death or proliferation
- Hydrogen-rich saline protects retina against glutamate-induced excitotoxic injury in guinea pig
- NAD (P) H oxidase contributes to neurotoxicity in an excitotoxic/prooxidant model of Huntington’s disease in rats: protective role of apocynin
- The G Protein‐Coupled Receptor 55 Ligand l‐α‐Lysophosphatidylinositol Exerts Microglia‐Dependent Neuroprotection After excitotoxic Lesion
- Magnesium sulfate prevents neurochemical and long-term behavioral consequences of neonatal excitotoxic lesions: comparison between male and female mice
- Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D …
- Growth hormone reverses excitotoxic damage induced by kainic acid in the green iguana neuroretina
- The mechanism of axonal degeneration after perikaryal excitotoxic injury to the retina
- Successful inhibition of excitotoxic neuronal damage and microglial activation after delayed application of interleukin‐1 receptor antagonist
- Neuroinflammation in glaucoma: soluble tumor necrosis factor alpha and the connection with excitotoxic damage
- Neuroprotection against excitotoxic brain injury in mice after ovarian steroid depletion
- Heme oxygenase-1 (HO-1) upregulation delays morphological and oxidative damage induced in an excitotoxic/pro-oxidant model in the rat striatum
- Neuroprotective potential of biphalin, multireceptor opioid peptide, against excitotoxic injury in hippocampal organotypic culture
- Apnea produces excitotoxic hippocampal synapses and neuronal apoptosis
- Necrotic death of neurons following an excitotoxic insult is prevented by a peptide inhibitor of c‐jun N‐terminal kinase
- Persistently altered metabolic phenotype following perinatal excitotoxic brain injury
- N -Methyl-d-Aspartate (NMDA)-Mediated excitotoxic Damage: A Mouse Model of Acute Retinal Ganglion Cell Damage
- Proteolytic fragments of laminin promote excitotoxic neurodegeneration by up-regulation of the KA1 subunit of the kainate receptor
- Mitochondrial dysfunction during the early stages of excitotoxic spinal motor neuron degeneration in vivo
- Reduced connexin43 expression correlates with c‐Src activation, proliferation, and glucose uptake in reactive astrocytes after an excitotoxic insult
- Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death
- Exploration of the glutamate-mediated retinal excitotoxic damage: a rat model of retinal neurodegeneration
- HIV-1, methamphetamine and astrocyte glutamate regulation: combined excitotoxic implications for neuro-AIDS
- Role of Energy Metabolic Deficits and Oxidative Stress in excitotoxic Spinal Motor Neuron Degeneration in Vivo
- Leonurine ameliorates cognitive dysfunction via antagonizing excitotoxic glutamate insults and inhibiting autophagy
- NMDA receptor-mediated neuroprotective effect of the Scutellaria baicalensis Georgi extract on the excitotoxic neuronal cell death in primary rat cortical cell …
- Astrocytic expressions of phosphorylated Akt, GSK3β and CREB following an excitotoxic lesion in the mouse hippocampus
- Neuroprotective effect of propofol against excitotoxic injury to locomotor networks of the rat spinal cord in vitro
- Antiepileptic and neuroprotective effects of oleamide in rat striatum on kainate-induced behavioral seizure and excitotoxic damage via calpain inhibition
- Intracranial V. cholerae sialidase protects against excitotoxic neurodegeneration
- Accurate timing but increased impulsivity following excitotoxic lesions of the subthalamic nucleus
- The PtdIns (3, 4) P 2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
- Fatherhood diminishes the hippocampal damaging action of excitotoxic lesioning in mice
- Novel application of stem cell-derived neurons to evaluate the time-and dose-dependent progression of excitotoxic injury
- Calpastatin overexpression protects against excitotoxic hippocampal injury and traumatic spinal cord injury
- Neuroprotective effect of the alpha 7 nicotinic receptor agonist PHA 543613 in an in vivo excitotoxic adult rat model
- Neuropeptide Y can rescue neurons from cell death following the application of an excitotoxic insult with kainate in rat organotypic hippocampal slice cultures
- Cytoplasmic calcium mediates oxidative damage in an excitotoxic/energetic deficit synergic model in rats
- Neuroprotective effects of pyruvate following NMDA-mediated excitotoxic insults in hippocampal slices
- Neuroprotective effects of R, R-tetrahydrochrysene against glutamate-induced cell death through anti-excitotoxic and antioxidant actions involving estrogen receptor …
- Enhanced neurogenesis in organotypic cultures of rat hippocampus after transient subfield-selective excitotoxic insult induced by domoic acid
- Tenascin‐R promotes neuronal differentiation of embryonic stem cells and recruitment of host‐derived neural precursor cells after excitotoxic lesion of the mouse …
- Using MRI to predict the fate of excitotoxic lesions in rats
- Glial expression of interleukin-18 and its receptor after excitotoxic damage in the mouse hippocampus
- excitotoxic lesion of the medial prefrontal cortex in Wistar rats: effects on trait and state anxiety
- Brain‐derived neurotrophic factor inhibits cell cycle reentry but not endoplasmic reticulum stress in cultured neurons following oxidative or excitotoxic stress
- Post‐training excitotoxic lesions of the dorsal hippocampus attenuate generalization in auditory delay fear conditioning
- Differential induction of rat neuronal excitotoxic cell death by human immunodeficiency virus type 1 clade B and C tat proteins
- Hydroxyurea attenuates oxidative, metabolic, and excitotoxic stress in rat hippocampal neurons and improves spatial memory in a mouse model of Alzheimer’s …
- Differential effect of oxidative or excitotoxic stress on the transcriptional profile of amyotrophic lateral sclerosis‐linked mutant SOD1 cultured neurons
- Live imaging of Kv7. 2/7.3 cell surface dynamics at the axon initial segment: high steady-state stability and calpain-dependent excitotoxic downregulation revealed
- Insulin-like growth factor 1 promotes cochlear synapse regeneration after excitotoxic trauma in vitro
- PIKfyve regulates CaV1. 2 degradation and prevents excitotoxic cell death
- CXCL16 orchestrates adenosine A3 receptor and MCP-1/CCL2 activity to protect neurons from excitotoxic cell death in the CNS
- Contribution of a mitochondrial pathway to excitotoxic neuronal necrosis
- Pharmacological activation/inhibition of the cannabinoid system affects alcohol withdrawal-induced neuronal hypersensitivity to excitotoxic insults
- Glia-mediated regenerative response following acute excitotoxic damage in the postnatal squamate retina
- Neuroprotection of dopamine neurons by xenon against low-level excitotoxic insults is not reproduced by other noble gases
- Acute neuronal injury: the role of excitotoxic programmed cell death mechanisms
- Delayed application of the haematopoietic growth factors G-CSF/SCF and FL reduces neonatal excitotoxic brain injury
- Prolactin neuroprotective action against excitotoxic insult in the hippocampus of male mice
- … open probability of α7 nAChR can be overcome by positive allosteric modulation and serum factors leading to the generation of excitotoxic currents at physiological …
- The AMPA receptor positive allosteric modulator, S18986, is neuroprotective against neonatal excitotoxic and inflammatory brain damage through BDNF synthesis
- Decreased myeloperoxidase expressing cells in the aged rat brain after excitotoxic damage
- excitotoxic cell death induces delayed proliferation of endogenous neuroprogenitor cells in organotypic slice cultures of the rat spinal cord
- Effects of parafascicular excitotoxic lesions on two-way active avoidance and odor-discrimination
- The recombinant human erythropoietin administered in neonatal rats after excitotoxic damage induces molecular changes in the hippocampus
- DGKζ is degraded through the cytoplasmic ubiquitin–proteasome system under excitotoxic conditions, which causes neuronal apoptosis because of aberrant cell …
- VEGF receptor antagonist Cyclo-VEGI reduces inflammatory reactivity and vascular leakiness and is neuroprotective against acute excitotoxic striatal insult
- … of a novel injury-induced calcium-permeable channel that plays a key role in causing extended neuronal depolarization and initiating neuronal death in excitotoxic …
- Human immunodeficiency virus-1 protein Tat induces excitotoxic loss of presynaptic terminals in hippocampal cultures
- Aging and excitotoxic stress exacerbate neural circuit reorganization in amyloid precursor protein intracellular domain transgenic mice
- Force spectroscopy measurements show that cortical neurons exposed to excitotoxic agonists stiffen before showing evidence of bleb damage
- Lipid markers and related transcripts during excitotoxic neurodegeneration in kainate‐treated mice
- Predifferentiated GABAergic neural precursor transplants for alleviation of dysesthetic central pain following excitotoxic spinal cord injury
- Non‐canonical activation of CREB mediates neuroprotection in a Caenorhabditis elegans model of excitotoxic necrosis
- Dextromethorphan is protective against sensitized N‐methyl‐d‐aspartate receptor‐mediated excitotoxic brain damage in the developing mouse brain
- The endocannabinoid N-arachidonoyldopamine (NADA) exerts neuroprotective effects after excitotoxic neuronal damage via cannabinoid receptor 1 (CB1)
- A Multi-Scale Computational Model of excitotoxic Loss of Dopaminergic Cells in Parkinson’s Disease
- Long-term evaluation of sensorimotor and mnesic behaviour following striatal NMDA-induced unilateral excitotoxic lesion in the mouse
- Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform
- Neuroprotection from excitotoxic injury by local administration of lipid emulsion into the brain of rats
- Spinal cord transcriptomic and metabolomic analysis after excitotoxic injection injury model of syringomyelia
- Altered sensitivity to excitotoxic cell death and glutamate receptor expression between two commonly studied mouse strains
- Mitochondrial ATP-Mg/Pi carrier SCaMC-3/Slc25a23 counteracts PARP-1-dependent fall in mitochondrial ATP caused by excitotoxic insults in neurons
- Role of p75NTR in NMDAR-mediated excitotoxic brain injury in neonatal mice
- excitotoxic lesions of the nucleus paragigantocellularis facilitate male sexual behavior but attenuate female sexual behavior in rats
- … modulate mitochondrial membrane potential and neurofilament light mRNA expression in cultured dorsal root ganglion and spinal cord neurons during excitotoxic …
- URB597 Prevents the Short-Term excitotoxic Cell Damage in Rat Cortical Slices: Role of Cannabinoid 1 Receptors
- Effects of excitotoxic lesion with inhaled anesthetics on nervous system cells of rodents
- excitotoxic neuronal cell death during an oligodendrocyte-directed CD8+ T cell attack in the CNS gray matter
- Cytisine confers neuronal protection against excitotoxic injury by down-regulating GluN2B-containing NMDA receptors
- MRI overestimates excitotoxic amygdala lesion damage in rhesus monkeys
- Melanopsin-Containing ipRGCs Are Resistant to excitotoxic Injury and Maintain Functional Non-Image Forming Behaviors After Insult in a Diurnal Rodent Model
- Dorsal, ventral, and complete excitotoxic lesions of the hippocampus in rats failed to impair appetitive trace conditioning
- Adenosine A2A receptor blockade before striatal excitotoxic lesions prevents long term behavioural disturbances in the quinolinic rat model of Huntington’s disease
- … signaling target, activating transcription factor 3 (ATF3), protects against dendrotoxicity and facilitates the recovery of synaptic transmission after an excitotoxic …
- excitotoxic insult results in a long-lasting activation of CaMKIIα and mitochondrial damage in living hippocampal neurons
- … hormone 1‐39 promotes proliferation and differentiation of oligodendroglial progenitor cells and protects from excitotoxic and inflammation‐related damage
- Neuroprotection against excitotoxic and ischemic insults by bis (12)-hupyridone, a novel anti-acetylcholinesterase dimer, possibly via acting on multiple targets
- excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord
- Glycogen synthase kinase-3/Shaggy mediates ethanol-induced excitotoxic cell death of Drosophila olfactory neurons
- excitotoxic neonatal damage induced by monosodium glutamate reduces several GABAergic markers in the cerebral cortex and hippocampus in adulthood
- Neuroprotective effects vary across nonsteroidal antiinflammatory drugs in a mouse model of developing excitotoxic brain injury
- IL-1RAcPb signaling regulates adaptive mechanisms in neurons that promote their long-term survival following excitotoxic insults
- Defects in cytokine-mediated neuroprotective glial responses to excitotoxic hippocampal injury in senescence-accelerated mouse
- Respiratory motoneurons and pathological conditions: lessons from hypoglossal motoneurons challenged by excitotoxic or oxidative stress
- Subfield-specific neurovascular remodeling in the entorhino-hippocampal-organotypic slice culture as a response to oxygen–glucose deprivation and excitotoxic cell …
- Silymarin Inhibits Glutamate Release and Prevents against Kainic Acid-Induced excitotoxic Injury in Rats
- excitotoxic lesions of the bed nucleus of the stria terminalis (BNST) attenuate the effects of repeated stress on weight gain: evidence for the recruitment of BNST …
- Lack of kainic acid‐induced gamma oscillations predicts subsequent CA1 excitotoxic cell death
- Temporal progression of excitotoxic calcium following distal middle cerebral artery occlusion in freely moving mice
- Regenerative effect of growth hormone (GH) in the retina after kainic acid excitotoxic damage
- Distinct spatial and temporal activation of caspase pathways in neurons and glial cells after excitotoxic damage to the immature rat brain
- Computational analysis of AMPK-mediated neuroprotection suggests acute excitotoxic bioenergetics and glucose dynamics are regulated by a minimal set of …
- Cortical expression of brain derived neurotrophic factor and type-1 cannabinoid receptor after striatal excitotoxic lesions
- The sigma-1 receptor agonist 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) protects against newborn excitotoxic brain injury by stabilizing the mitochondrial …
- A prolonged pharmacological blockade of type-5 metabotropic glutamate receptors protects cultured spinal cord motor neurons against excitotoxic death
- Effect of Rufinamide on the kainic acid-induced excitotoxic neuronal death in the mouse hippocampus
- T3 replacement does not prevent excitotoxic cell death but reduces developmental neuronal apoptosis in newborn mice
- … of persistent organic pollutants (POPs) and perfluorooctane sulfonic acid (PFOS) differentially affect glutamate induced excitotoxic responses in chicken …
- Modulation of the magnitude of conditioned taste aversion in rats with excitotoxic lesions of the basolateral amygdala
- Absence of striatal newborn neurons with mature phenotype following defined striatal and cortical excitotoxic brain injuries
- Effect of the PARP-1 inhibitor PJ 34 on excitotoxic damage evoked by kainate on rat spinal cord organotypic slices
- Nicotine protects rat hypoglossal motoneurons from excitotoxic death via downregulation of connexin 36
- Temporal dependence of cysteine protease activation following excitotoxic hippocampal injury
- Haloperidol treatment after high-dose methamphetamine administration is excitotoxic to GABA cells in the substantia nigra pars reticulata
- The effect of pro-neurogenic gene expression on adult subventricular zone precursor cell recruitment and fate determination after excitotoxic brain injury
- The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation
- Exacerbation of excitotoxic neuronal death induced during mitochondrial inhibition in vivo: relation to energy imbalance or ATP depletion?
- Multicompartment Microreactors Prevent excitotoxic Dysfunctions In Rat Primary Cortical Neurons
- Morphometric analysis of NADPH diaphorase reactive neurons in a rat model of focal excitotoxic striatal injury
- excitotoxic-mediated transcriptional decreases in HCN2 channel function increase network excitability in CA1
- Increased expression of acyl-coenzyme A: cholesterol acyltransferase-1 and elevated cholesteryl esters in the hippocampus after excitotoxic injury
- Stress exacerbates neuron loss and microglia proliferation in a rat model of excitotoxic lower motor neuron injury
- Melanocortin receptor agonist ACTH 1–39 protects rat forebrain neurons from apoptotic, excitotoxic and inflammation-related damage
- Purinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: roles in the outcome of excitotoxic brain injury
- An organotypic hippocampal slice culture model of excitotoxic injury induced spontaneous recurrent epileptiform discharges
- Serial EEG and MRI changes in status epilepticus-induced excitotoxic neuronal necrosis
- … D modulates F2-isoprostane and 7-ketocholesterol formation and has a neuroprotective effect on organotypic hippocampal cultures after kainate-induced excitotoxic …
- Involvement of VIP and PACAP in neonatal brain lesions generated by a combined excitotoxic/inflammatory challenge
- Minimal impairment in a rat model of duration discrimination following excitotoxic lesions of primary auditory and prefrontal cortices
- Spinal and supraspinal changes in tumor necrosis factor-α expression following excitotoxic spinal cord injury
- Serial deletion reveals structural basis and stability for the core enzyme activity of human glutaminase 1 isoforms: relevance to excitotoxic neurodegeneration
- excitotoxic SLC7A11 expression is a marker of poor glioblastoma survival and a potential therapeutic target
- Selenium-induced antioxidant protection recruits modulation of thioredoxin reductase during excitotoxic/pro-oxidant events in the rat striatum
- excitotoxic insults lead to peroxiredoxin hyperoxidation
- … , a subpopulation spared in Huntington’s Disease, possess functional NMDA receptors but fail to generate mitochondrial ROS in response to an excitotoxic …
- Investigation of elemental changes in brain tissues following excitotoxic injury
- Protective effect of valproic acid on cultured motor neurons under glutamate excitotoxic conditions. Ultrastructural study
- Neuropathological characterization of spinal motor neuron degeneration processes induced by acute and chronic excitotoxic stimulus in vivo
- Loss of high‐affinity nicotinic receptors increases the vulnerability to excitotoxic lesion and decreases the positive effects of an enriched environment
- Complement component 3 (C3) expression in the hippocampus after excitotoxic injury: role of C/EBPβ
- excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1
- Anti-apoptotic therapy with a Tat fusion protein protects against excitotoxic insults in vitro and in vivo
- Distinct pattern of microglial response, cyclooxygenase‐2, and inducible nitric oxide synthase expression in the aged rat brain after excitotoxic damage
- Aprotinin confers neuroprotection by reducing excitotoxic cell death
- Donepezil attenuates excitotoxic damage induced by membrane depolarization of cortical neurons exposed to veratridine
- Ketone bodies attenuate excitotoxic cell injury in the rat hippocampal slice under conditions of reduced glucose availability
- Growth differentiation factor 15 expression in astrocytes after excitotoxic lesion in the mouse hippocampus
- excitotoxic motoneuron disease in chick embryo evolves with autophagic neurodegeneration and deregulation of neuromuscular innervation
- The use of propidium iodide to assess excitotoxic neuronal death in primary mixed cortical cultures
- PI3K mediated activation of GSK-3β reduces at-level primary afferent growth responses associated with excitotoxic spinal cord injury dysesthesias
- Differential patterns of inflammatory response, axonal damage and myelin impairment following excitotoxic or ischemic damage to the trigeminal spinal nucleus of …
- Prognostic value of MR spectroscopy in patients with acute excitotoxic encephalopathy
- Regenerative effect of a ROCK inhibitor, Y-27632, on excitotoxic trauma in an organotypic culture of the cochlea
- excitotoxic protection by polyanionic polysaccharide: Evidence of a cell survival pathway involving AMPA receptor–MAPK Interactions
- excitotoxic lesion of the hippocampus of Wistar rats disrupts the circadian control of the latent inhibition of taste aversion learning
- Pattern of injury with a graded excitotoxic insult and ensuing chronic medial septal damage in the rat brain
- Peroxisome proliferator‐activated receptor‐γ coactivator‐1α mediates neuroprotection against excitotoxic brain injury in transgenic mice: role of mitochondria and X …
- Reduction of Prepulse Inhibition (PPI) after neonatal excitotoxic lesion of the ventral thalamus in pubertal and adult rats
- Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo
- Calpain inhibition protects spinal motoneurons from the excitotoxic effects of AMPA in vivo
- An explanation of why schizophrenia begins with excitotoxic damage to the hippocampus
- ID4 mediates proliferation of astrocytes after excitotoxic damage in the mouse hippocampus
- Suppression to visual, auditory and gustatory stimuli habituates normally in rats with excitotoxic lesions of the perirhinal cortex
- Dibutyryl cyclic adenosine monophosphate rescues the neurons from degeneration in stab wound and excitotoxic injury models
- Neuroprotection by α2-adrenergic receptor stimulation after excitotoxic retinal injury: a study of the total population of retinal ganglion cells and their …
- Transgenic overexpression of corticotropin releasing hormone provides partial protection against neurodegeneration in an in vivo model of acute excitotoxic stress
- Transglutaminase 2 interaction with small heat shock proteins mediate cell survival upon excitotoxic stress
- Essential role of PIKE GTPases in neuronal protection against excitotoxic insults
- Effect of prefrontal cortex inactivation on behavioral and neurochemical abnormalities in rats with excitotoxic lesions of the entorhinal cortex
- Effect of pioglitazone on excitotoxic neuronal damage in the mouse hippocampus
- Latent inhibition of conditioned taste aversion in rats with excitotoxic dorsal hippocampal lesions
- AC105 increases extracellular magnesium delivery and reduces excitotoxic glutamate exposure within injured spinal cords in rats
- The proapoptotic BCL-2 homology domain 3-only protein Bim is not critical for acute excitotoxic cell death
- Memantine prevents sensitivity to excitotoxic cell death of rat cortical neurons expressing human truncated tau protein
- Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents
- CGX-1007 prevents excitotoxic cell death via actions at multiple types of NMDA receptors
- Cyclin D1 induction preceding neuronal death via the excitotoxic NMDA pathway involves selective stimulation of extrasynaptic NMDA receptors and JNK pathway
- Astrocytic phosphorylation of PDK1 on Tyr9 following an excitotoxic lesion in the mouse hippocampus
- The spatiotemporal pattern of somal and axonal pathology after perikaryal excitotoxic injury to retinal ganglion cells: a histological and morphometric study
- The new iminothiadiazole derivative VP1. 14 ameliorates hippocampal damage after an excitotoxic injury
- The kinetics of non-synaptically triggered acute excitotoxic responses in the central nervous system observed using intrinsic optical signals
- Hepatocyte growth factor improves synaptic localization of the NMDA receptor and intracellular signaling after excitotoxic injury in cultured hippocampal neurons
- Neuroprotective effects of C3 exoenzyme in excitotoxic retinopathy
- Sex and regional differences in effects of chronic intermittent ethanol exposure on subsequent excitotoxic challenges in hippocampal slice cultures
- Intracisternal IGF‐1 gene therapy abrogates kainic acid‐induced excitotoxic damage of the rat spinal cord
- IQGAP1 expression in spared CA1 neurons after an excitotoxic lesion in the mouse hippocampus
- excitotoxic spinal cord injury induced dysesthesias are associated with enhanced intrinsic growth of sensory neurons
- Sex differences in effects of excitotoxic spinal injury on below-level pain sensitivity
- The developmental expression of fluorescent proteins in organotypic hippocampal slice cultures from transgenic mice and its use in the determination of excitotoxic …
- Bax deficiency promotes an up-regulation of BimEL and Bak during striatal and cortical postnatal development, and after excitotoxic injury
- Retinal safety of intravitreal rtPA in healthy rats and under excitotoxic conditions
- Tex261 modulates the excitotoxic cell death induced by N-methyl-D-aspartate (NMDA) receptor activation
- excitotoxic effects of glutamate on cochlear organotypic cultures
- Response disengagement on a spatial self-ordered sequencing task: effects of regionally selective excitotoxic lesions and serotonin depletion within the prefrontal …
- Modifications in the Seizures Susceptibility by excitotoxic Neuronal Damage and Its Possible Relationship with the Pharmacoresistance
- excitotoxic lesions of the medial amygdala attenuate olfactory fear-potentiated startle and conditioned freezing behavior
- Studies of locomotor network neuroprotection by the selective poly(ADP‐ribose) polymerase‐1 inhibitor PJ‐34 against excitotoxic injury to the rat spinal cord in vitro
- Targeting IKK2 by pharmacological inhibitor AS602868 prevents excitotoxic injury to neurons and oligodendrocytes
- RhoGDI2 expression in astrocytes after an excitotoxic lesion in the mouse hippocampus
- Effects of dimeric PSD-95 inhibition on excitotoxic cell death and outcome after controlled cortical impact in rats
- Central pain from excitotoxic spinal cord injury induced by intraspinal NMDA injection: a pilot study
- Effects of neonatal excitotoxic lesions in ventral thalamus on social interaction in the rat
- An approach for neuroprotective therapies of secondary brain damage after excitotoxic retinal injury in mice
- Inflammation and neuronal susceptibility to excitotoxic cell death
- excitotoxicity Alters Endogenous Secretoneurin Plasma Levels, but Supplementation with Secretoneurin Does Not Protect Against excitotoxic Neonatal Brain Injury
- excitotoxic programmed cell death involves caspase-independent mechanisms
- … and altered glutamic acid decarboxylase (GAD) 65-and 67-kDa isoform protein expression from mouse cortical GABAergic neurons following excitotoxic injury in vitro
- Astrocytic insulin‐like growth factor‐1 prevents excitotoxic downregulation of adenosine deaminase acting on RNA in calcium dynamics
- excitotoxic lesions of the rodent striatum
- Repair of glutamate-induced excitotoxic neuronal damage mediated by intracerebroventricular transplantation of neural stem cells in adult mice
- excitotoxic potential of exogenous ferritin and apoferritin: Changes in ambient level of glutamate and synaptic vesicle acidification in brain nerve terminals
- Congenic strains provide evidence that a mapped locus on chromosome 15 influences excitotoxic cell death
- A quantitative trait locus on chromosome 18 is a critical determinant of excitotoxic cell death susceptibility
- Change of Nurr1 expression in mouse hippocampal CA3 region following excitotoxic neuronal damage
- excitotoxic lesion of the posterior part of the dorsal striatum does not affect the typically dopaminergic phenomenon of latent inhibition in conditioned taste aversion
- Overexpression of the nuclear factor kappaB inhibitor A20 is neurotoxic after an excitotoxic injury to the immature rat brain
- Exogenous GDNF increase the migration of the neural stem cells with no protection against kainic acid-induced excitotoxic cell death in rats
- excitotoxic injury to thoracolumbar gray matter alters sympathetic activation and thermal pain sensitivity
- Paraoxon: an anticholinesterase that triggers an excitotoxic cascade of oxidative stress, adhesion responses, and synaptic compromise
- … brain expression of both nerve growth factor and high-affinity receptor TrkA, and reverses memory and cognitive deficits, in rats with excitotoxic lesion of nucleus …
- Microglia express functional NMDA receptors: a novel finding and a promise for innovative treatment of excitotoxic and inflammatory brain disease
- Dynamics of Trace Element Concentration During Development and excitotoxic Cell Death in the Cerebellum of Lurcher Mutant Mice
- Exosomes secretion and autophagy in long-term protection of neurons from excitotoxic damage
- Pyruvate blocks blood-brain barrier disruption, lymphocyte infiltration and immune response in excitotoxic brain injury
- Simultaneous two-voxel localized 1H-observed 13C-edited spectroscopy for in vivo MRS on rat brain at 9.4 T: Application to the investigation of excitotoxic lesions
- Urocortin 2 treatment is protective in excitotoxic retinal degeneration
- Aprotinin, but not ε-aminocaproic acid and tranexamic acid, exerts neuroprotection against excitotoxic injury in an in vitro neuronal cell culture model
- Glutamate decarboxylase protects neurons against excitotoxic injury
- Impaired sensitivity to Pavlovian stimulus–outcome learning after excitotoxic lesion of the ventrolateral neostriatum
- A model of excitotoxic brain injury in larval zebrafish: potential application for high-throughput drug evaluation to treat traumatic brain injury
- Localization of the transcription factor, sterol regulatory element binding protein-2 (SREBP-2) in the normal rat brain and changes after kainate-induced excitotoxic …
- Ecdysterones from Rhaponticum carthamoides (Willd.) Iljin reduce hippocampal excitotoxic cell loss and upregulate mTOR signaling in rats
- … survival of adult neural stem cells generated physiologically in the hippocampus, but does not protect stem cells generated in surplus after an excitotoxic …
- Prostacyclin mediates endothelial COX-2-dependent neuroprotective effects during excitotoxic brain injury
- Susceptibility to seizure-induced excitotoxic cell death is regulated by an epistatic interaction between Chr 18 (Sicd1) and Chr 15 (Sicd2) loci in mice
- excitotoxic lesion of the perirhinal cortex impairs spatial working memory in a delayed-alternation task
- Cytotoxic and Anti-excitotoxic Effects of Selected Plant and Algal Extracts Using Comet and Cell Viability Assays
- Exosomes Secretion and Autophagy in Long-Term Protection of Neurons from excitotoxic Damage
- Intrastriatal excitotoxic lesion or dopamine depletion of the neostriatum differentially impairs response execution in extrapersonal space
- GRK2 and group I mGluR mediate inflammation-induced sensitization to excitotoxic neurodegeneration
- An Atlas of Phosphorylation and Proteolytic Processing Events During excitotoxic Neuronal Death Reveals New Therapeutic Opportunities
- Effects of behavioral and neurochemical changes on adult excitotoxic lesion of the ventral hippocampus
- excitotoxic lesions to the prefrontal cortex of Sprague–Dawley rats do not impair response matching
- Trophic factors deprivation induces long-term protection of neurons against excitotoxic damage
- Effect of pharmacological modulation of activity of metabotropic glutamate receptors on their gene expression after excitotoxic damage in hippocampal neurons
- Acute neuronal injury: the role of excitotoxic programmed cell death mechanisms
- excitotoxic Mechanisms in Non-Motor Dysfunctions and Levodopa-Induced Dyskinesia in Parkinson’s Disease: The Role of the Interaction Between the Dopaminergic …
- Regeneration of Cochlear Synapses after excitotoxic Trauma
- … of L-serine biosynthetic enzyme 3-phosphoglycerate dehydrogenase (Phgdh) and neutral amino acid transporter ASCT1 following an excitotoxic lesion in the mouse …
- Differential Neuroprotective Effects of Interleukin-1 Receptor Antagonist on Spinal Cord Neurons after excitotoxic Injury
- excitotoxic perirhinal cortex lesions leave stimulus-specific habituation of suppression to lights intact
- Development of an acute excitotoxic model of Huntington’s disease in sheep
- Early postnatal ethanol exposure: glutamatergic excitotoxic cell death during acute withdrawal
- In vitro evidence for post-insult neuroprotective activity of an evolutionarily conserved motif against excitotoxic neuronal cell death
- Role of NADPH oxidase-2 in the progression of the inflammatory response secondary to striatum excitotoxic damage
- Multi-ancestry genetic study in 5,876 patients identifies an association between excitotoxic genes and early outcomes after acute ischemic stroke
- The effect of ginsenoside Rd on the intracellular free calcium after excitotoxic injury in cultured cortical neurons [J]
- l‐dopa‐induced dyskinesias in unilateral 6‐hydroxydopamine‐lesioned rats are not modified by excitotoxic lesion of the entopeduncular nucleus and substantia nigra …
- Spasticity as an ictal pattern due to excitotoxic upper motor neuron damage
- Ethyl pyruvate does not require microglia for mediating neuroprotection after excitotoxic injury
- Neurobehavioral function of neonatal mice following excitotoxic brain damage
- Astrocytic expression of CTMP following an excitotoxic lesion in the mouse hippocampus
- Cyclosporine a protects RGC-5 cells from excitotoxic cell death
- A study of cannabinoid-1 receptors during the early phase of excitotoxic damage to rat spinal locomotor networks in vitro
- Kainic acid-induced seizures: inflammation and excitotoxic neuronal damage in the developing rat hippocampus
- Procedural performance benefits after excitotoxic hippocampal lesions in the rat sequential reaction time task
- Reduced size of the dendritic tree does not protect Purkinje cells from excitotoxic death
- excitotoxic Stimulation of Brain Microslices as an In vitro Model of Stroke
- Comparison of the effects of perinatal and neonatal administration of sodium ferulate on repair following excitotoxic neuronal damages induced by maternal …
- Author Correction: excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1
- Neuroprotective effect of estradiol-loaded poly (lactic-co-glycolic acid) nanoparticles on glutamate-induced excitotoxic neuronal death
- Microreactors: Multicompartment Microreactors Prevent excitotoxic Dysfunctions In Rat Primary Cortical Neurons (Adv. Biosys. 10/2020)
- Genes on distal chromosome 18 determine vulnerability to excitotoxic neurodegeneration following status epilepticus, but not striatal neurodegeneration induced by …
- Investigating the effects of excitotoxic stimuli on the suprachiasmatic nucleus
- Cysteine-Mediated excitotoxic Neuronal Death is an Apoptosis—Necrosis Continuum
- excitotoxic programmed cell death involves caspase-independent mechanisms
- In vivo assessment of experimental neonatal excitotoxic brain lesion with USPIO-enhanced MR imaging
- The neonatal excitotoxic process modifies the protein expression levels of EAAT1 (GLAST) and EAAT2 (GLT-1) in various brain regions of the adult rat brain.
- Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-PI3K-Akt pathway through its SHBG-like region
- EFFECTS OF excitotoxic LESION WITH INHALED ANESTHETICS ON NERVOUS SYSTEM CELLS OF RODENTS
- excitotoxic Injury Mechanisms in Central White Matter
- The GluK4 Kainate Receptor Subunit Regulates Mood, Memory and excitotoxic Neurodegeneration
- Key proteins of activating cell death can be predicted through a kainic acid-induced excitotoxic stress
- Neuroprotective strategies in excitotoxic brain injury: potential applications to the preterm brain
- Neuroprotection from excitotoxic RGC death: is there a role for MMPs?
- Ambivalent action of cyclic AMP on degeneration and regeneration of cochlear afferent synapses during and after excitotoxic trauma
- Kinetic Model of AMPK-mediated Autophagy as excitotoxic Stress Response
- Enhancement of endogenous cannabinoid responses through FAAH inhibition provides cellular and functional protection against excitotoxic brain damage.
- The excitotoxic impairment of brain in patients with discirculatory encephalopathyand therapeutic correction
- Transient sublethal excitotoxic stress and its connections to long term neurodegeneration in primary neurons.
- Neural crest stem cells protect spinal cord slice cultures from excitotoxic neuronal damage and inhibit glial activation
- excitotoxic PATHOLOGY: DESCRIPTION OF A MODEL IN THE VISUAL SYSTEM OF MICE
- Modeling excitotoxic ischemic brain injury of cerebellar Purkinje neurons by intravital and in vitro multi-photon laser scanning microscopy
- Effects of age on chick light adapted ERGs with and without inner retinal excitotoxic damage
- Intracellular zinc mobilization is required for nNOS (+) neuron loss. Role of zinc in the excitotoxic cascade
- Persistently altered metabolic phenotype following perinatal excitotoxic brain injury
- Longitudinal assessments of retinal degeneration after excitotoxic injury using an end-to-end pipeline with deep learning-based automatic layer segmentation
- excitotoxic Injury to Retinal Ganglion Cells
- Effects of furin inhibitors on excitotoxic neuronal damage
- FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for Gria2 mRNA processing
- VGLUT1 and VGLUT2 cleavage under excitotoxic conditions and in cerebral ischemia
- Exploring the signalling mechanism of excitotoxic neuronal injury by molecular and quantitative proteomic approaches
- Effect of Triiodothyronine on Brain Pathological Lesion and Expressions of Caspase-3 and Myelin Basic Protein after excitotoxic Brain Injury in Neonatal Mice
- Lipid alterations in excitotoxic brain injury
- excitotoxic MECHANISMS, NEUROINFLAMMATORY RESPONSE AND SERUM FACTORS IN EXPERIMENTAL AND HUMAN AMYOTROPHIC LATERAL …
- Synthesis and Anti-oxidant/Anti-excitotoxic Activity of (1S)-(-) Verbenone Derivatives
- The Mechanism of Axonal Degeneration after Perikaryal excitotoxic Injury to the Retina
- VGLUT1 and VGLUT2 cleavage under excitotoxic conditions and in cerebral ischemia
- Distinct Roles of Cyclooxygenase-1 and Cyclooxygenase-2 in Inflammatory and excitotoxic Brain Injury
- Investigating the role of c-Src in excitotoxic neuronal death
- Role of excitotoxic Programmed Necrosis in Acute Brain Injury
- MIF Inhibitor Ibudilast Prevents Retinal Cell Death in Chick excitotoxic Retinal Damage Model
- Assessment of the Involvement of Intrinsic and Extrinsic Cell Death Pathways in Retinal Ganglion Cell Death after excitotoxic Injury
- Retinal MMP expression is upregulated in an excitotoxic mouse model of glaucoma
- Developing novel therapeutics for excitotoxic neuronal death following stroke
- Studying the excitotoxic Amino Acids Impact on the Degree of Impairment of Consciousness in Purulent Meningitises in Children
- Therapeutic Proposals for Childhood Status Epilepticus-Induced excitotoxic Neuronal Injury
- Characterisation of calpain activation in response to excitotoxic events in primary neurons
- Animal Models of Cerebral Dysgenesis: excitotoxic Brain Injury
- Abstract TP264: Actin Reorganization is a Rapid and Reversible Adaptive Response by Neurons Exposed to Ischemic and excitotoxic Injury in vitro and in vivo
- Effects of visual inputs on recovery after excitotoxic lesion of visual cortex
- Regulatory Role of HIF-1α in the SH-SY5Y Cells excitotoxic Injury
- The role of adenosine A2A receptors in regeneration of afferent synapses in the cochlea after excitotoxic injury
- Detecting Acute Inner Retinal excitotoxic Injury in Mice Using Diffusion MRI
- Bioluminescent Imaging of excitotoxic and Endotoxic Brain Injury in Living Mice
- Aspects of retinal and optic nerve pathology after excitotoxic retinal injury.
- excitotoxic Cell Death Mediated by Ca2+-Permeable Ampa Receptors is Coupled to the JNK Signalling Pathway
- Regulation of GABA receptors under excitotoxic conditions: contribution to neuronal death and potential implications to novel therapeutic approaches
- The interplay of JNK and SCG10 during cortical development and in excitotoxic responses in brain
- IL-1β conveys neuroprotection via astrocytic IL1R1 signaling following excitotoxic retinal injury
- Effects of triiodothyronine on the learning and memory behaviors in neonatal mice following excitotoxic brain damage
- Glial response to 17β-estradiol in neonatal rats with excitotoxic brain injury
- ROLE OF REACTIVE OXIGEN SPECIES IN THE REGULATION OF NEUROINFLAMMATION INDUCED BY excitotoxic DAMAGE IN CEREBELLAR …
- Abstract TP281: Increased Susceptibility to excitotoxic Injury in Rat Hippocampal Slices Exposed to Intermittent Hypoxia
- The role of glutamate in immune cell infiltration and excitotoxic mechanisms in autoimmune demyelination
- A new transgenic mouse model for studying the neurotoxicity of spermine oxidase dosage in the response to excitotoxic injury
- Inflammation in excitotoxic neuronal death and survival: involvement of tumor necrosis factor-α and interleukin-1β
- The Neuroprotective Qualities of Creatine on Rat Retinal Cultures Exposed to Glutamate-Induced excitotoxic Injury
- Role of PTEN nuclear translocation in excitotoxic and ischemic neuronal injuries following stroke
- A New Transgenic Mouse Model for Studying the Neurotoxicity of Spermine Oxidase Dosage in the Response to excitotoxic Injury
- Neuroprotective roles for apelin, a novel neuropeptide, in HIV-associated excitotoxic injury
- The Role of Transcription Factors in Regulating Adult Neurogenesis after excitotoxic Brain Injury
- Somatic Injury Precedes Distal Atrophy Following excitotoxic Hippocampal Insult
- Calcineurin mediated CREB phosphorylation regulate hippocampal neuron death in excitotoxic rats
- Real-time imaging analysis and functional characterisation of transcription factor NF-kappaB activation in a model of excitotoxic injury in rat neurons.
- Endogenous WNT/β-catenin signaling in Müller cells protects retinal ganglion cells against excitotoxic damage
- The role of calpains on TrkB and Gephyrin cleavage under excitotoxic conditions: Characterization and functional implications
- Protecting Inner Hair Cell-Spiral Ganglion Neuron Synapses from excitotoxic Trauma
- Spatial memory impairments following excitotoxic lesions of the basal forebrain noncholinergic neuronal ensembles
- Tau Hyperphosphorylation In Retinal Ganglion Cells Is Associated With Reduced Axonal Transport And Enhanced Sensitivity To excitotoxic Injury
- Asymmetric dimethylarginine protects PC12 cells against glutamate-induced excitotoxic damage
- A new function for an old enzyme: Src protein tyrosine kinase directs excitotoxic neuronal death in stroke (596.3)
- Inhibition of excitotoxic and Aβ (25-35)-induced Neuronal Damage by Fractions Prepared from Mangosteen Pericarp in Primary Cultured Rat Cortical Cells
- Effects of clozapine (CLZ) on reduced prepulse inhibition (PPI) after neonatal excitotoxic lesion of the ventral thalamus in pubertal and adult rats
- Protein S protects neurons from excitotoxic injury by activating the TAM receptor Tyro3-PI3K-Akt pathway through its SHBG-like region
- … enhances brain expression of nerve growth factor and high-affinity receptor TrkA, and reverses memory and cognitive deficits, in rats with excitotoxic lesion of nucleus …
- PO-0472 Evaluation Of Secretoneurin As Therapeutic Strategy In Neonatal excitotoxic Brain Injury
- O-216 Melatonine Reduces Bbb Breakdown In A Rat Model Of Neonatal excitotoxic Damage
- 671. Gene Delivery to the Bone Marrow Targeting CCR5 Can Protect the CNS from In. ammation and In. ammation-Related excitotoxic Neuron Loss
- 299 PRE-084, A Sigma-1 Receptor Ligand, Protects Against excitotoxic Perinatal Brain Injury in Newborn Mice
- 197 P75 Ntr is Upregulated After Nmdar-Mediated excitotoxic Brain Injury in Newborn Mice
- Effects of Novel Benzofuran-2-carboxamide Derivatives on the excitotoxic Neuronal Damage in Primary Cultured Rat Cortical Cells
- L-trans-pyrrolidine-2, 4-dicarboxylate (PDC) induces excitotoxic and Oxidative Neuronal Death in Cultured Cortical Neurons
- Neuroprotection with Melatonin and the Caspase-2 Inhibitor TRP601: Novel Aspects by Analysis of the Metabolome in excitotoxic Brain Injury
- Effects of erythropoietin on neuron apoptosis and expression of caspase-3 after excitotoxic brain injury in mice during different developmental stages
- 311 The Sigma-Receptor-Agonist 4-Phenyl-1-(4-Phenylbutyl) Piperidine (PPBP) Decreases Neonatal excitotoxic Brain Injury and Diminishes Microglial Cell Activation
- Insulin-Like Growth Factor 1 (IGF1) Stimulates a Novel Type of Glia-Like Cell in the Retina and Renders Neurons Susceptible to excitotoxic Damage
- … is not mandatory for neuroprotection with 1alpha, 25-dihydroxyvitamin D3 in perinatal hypoxic-ischemic rat brain damage in vivo and in excitotoxic injury of primary …
- 195 The Selective Sigma-1 Receptor Agonist Pre-084 Reduces Ndmar-Mediated excitotoxic Brain Injury in Newborn Mice
- 9 The Sigma-1 Receptor Agonist PRE-084 Attenuates Inflammation-Sensitized Nmdar-Mediated excitotoxic Brain Injury in Newborn Mice
- Chapter’1 1 excitotoxic Lesions of the Developing Brain
- Mechanisms of Interleukin-1 (IL-1) Induced excitotoxic Neurodegeneration
- Mechanisms of excitotoxicity in neurologic diseases
- excitotoxicity hypothesis
- The role of excitotoxicity in neurodegenerative disease: implications for therapy
- excitotoxicity: an overview.
- Glutamate excitotoxicity in a model of multiple sclerosis
- Molecular mechanisms of calcium-dependent excitotoxicity
- The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis
- Apoptosis, excitotoxicity, and neuropathology
- Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
- The role of excitotoxicity in neurodegeneration.
- excitotoxicity in perinatal brain injury
- excitotoxicity, free radicals, and cell membrane changes
- Involvement of free radicals in excitotoxicity in vivo
- Pictorial review of glutamate excitotoxicity: fundamental concepts for neuroimaging
- excitotoxicity and nitric oxide in Parkinson’s disease pathogenesis
- The relationship between excitotoxicity and oxidative stress in the central nervous system
- excitotoxicity
- excitotoxicity and amyotrophic lateral sclerosis
- Possible role of excitotoxicity in the pathogenesis of glaucoma
- excitotoxicity in glial cells
- Bioenergetics and glutamate excitotoxicity
- Biochemical abnormalities and excitotoxicity in Huntington’s disease brain
- Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer’s disease
- Traumatic brain injury‐induced excitotoxicity assessed in a controlled cortical impact model
- Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts
- excitotoxicity in neonatal hypoxia
- A proposed role for excitotoxicity in glaucoma
- Kainic acid-mediated excitotoxicity as a model for neurodegeneration
- Glutamate, excitotoxicity and amyotrophic lateral sclerosis
- excitotoxicity, apoptosis and neuropsychiatric disorders
- The role of excitotoxicity in ALS–what is the evidence?
- The role of excitotoxicity in secondary mechanisms of spinal cord injury: a review with an emphasis on the implications for white matter degeneration
- Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity
- Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
- Role of excitotoxicity in human neurological disease
- beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
- Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging
- Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene
- Oxidative glutamate toxicity can be a component of the excitotoxicity cascade
- CB1 cannabinoid receptors and on-demand defense against excitotoxicity
- Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: a perspective on the contributions of apoptosis and necrosis
- NMDA receptor-dependent excitotoxicity: the role of intracellular Ca2+ release
- N-methyl-D-aspartate receptor subtypes: multiple roles in excitotoxicity and neurological disease
- Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases
- excitotoxicity and selective neuronal loss in epilepsy
- excitotoxicity and alcohol‐related brain damage
- excitotoxicity and neurodegeneration in amyotrophic lateral sclerosis.
- Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity
- An experimental basis for implicating excitotoxicity in glaucomatous optic neuropathy
- Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis
- excitotoxicity: a possible central mechanism in fluoride neurotoxicity
- The role of excitotoxicity in organophosphorous nerve agents central poisoning
- Inflammation and excitotoxicity: role in migraine pathogenesis
- excitotoxicity, synaptic repair, and functional recovery in the mammalian cochlea: a review of recent findings
- excitotoxicity and new antiglutamatergic strategies in Parkinson’s disease and Alzheimer’s disease
- Calpain-mediated mGluR1α truncation: a key step in excitotoxicity
- excitotoxicity: perspectives based onN-methyl-D-aspartate receptor subtypes
- Potential target sites in peripheral tissues for excitatory neurotransmission and excitotoxicity
- Mitochondria and neuronal glutamate excitotoxicity
- Pathophysiology of oligodendroglial excitotoxicity
- Neuroprotection by two polyphenols following excitotoxicity and experimental ischemia
- Role of astrocytes in glutamate homeostasis: implications for excitotoxicity
- excitotoxicity in neurological disorders—the glutamate paradox
- Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity
- excitotoxicity in ALS
- Mitochondrial dysfunction and glutamate excitotoxicity studied in primary neuronal cultures
- excitotoxicity in vitro by NR2A-and NR2B-containing NMDA receptors
- Is high extracellular glutamate the key to excitotoxicity in traumatic brain injury?
- Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity
- Neuroprotective properties of memantine in different in vitro and in vivo models of excitotoxicity
- A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia
- Wild‐type huntingtin protects neurons from excitotoxicity
- Interleukin‐1β promotes oligodendrocyte death through glutamate excitotoxicity
- Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia
- Subthalamic nucleus‐mediated excitotoxicity in Parkinson’s disease: a target for neuroprotection
- Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington’s disease
- N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington’s disease
- excitotoxicity and neurodegenerative diseases.
- Glutamate uptake by oligodendrocytes: Implications for excitotoxicity in multiple sclerosis
- Neurochemical aspects of excitotoxicity
- Dendritic and mitochondrial changes during glutamate excitotoxicity
- Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity
- Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2
- Neuronal excitotoxicity: the role of mitochondria
- Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells
- Involvement of brain‐derived neurotrophic factor in cannabinoid receptor‐dependent protection against excitotoxicity
- excitotoxicity and repair of cochlear synapses after noise-trauma induced hearing loss
- Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity
- Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress
- Invulnerability of retinal ganglion cells to NMDA excitotoxicity
- Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage
- Intracellular calcium levels during the period of delayed excitotoxicity
- Bioenergetics of mitochondria in cultured neurons and their role in glutamate excitotoxicity
- Growth factors and taurine protect against excitotoxicity by stabilizing calcium homeostasis and energy metabolism
- Mitochondrial membrane potential and glutamate excitotoxicity in cultured cerebellar granule cells
- Na-K-Cl cotransporter contributes to glutamate-mediated excitotoxicity
- Molecular mechanisms of cannabinoid protection from neuronal excitotoxicity
- The stress protein response in cultured neurons: characterization and evidence for a protective role in excitotoxicity
- Neuroprotective effects of atorvastatin against glutamate‐induced excitotoxicity in primary cortical neurones
- Caspase-mediated apoptosis in neuronal excitotoxicity triggered by nitric oxide
- Acute neuronal injury, excitotoxicity, and the endocannabinoid system
- Selenium deficiency increases susceptibility to glutamate‐induced excitotoxicity
- Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity
- excitotoxicity, oxidative stress, and the neuroprotective potential of melatonin
- Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo
- 17β-Estradiol protects against NMDA-induced excitotoxicity by direct inhibition of NMDA receptors
- Mechanisms of ionotropic glutamate receptor-mediated excitotoxicity in isolated spinal cord white matter
- Inflammatory neurodegeneration mediated by nitric oxide from activated glia-inhibiting neuronal respiration, causing glutamate release and excitotoxicity
- Chronic ethanol exposure potentiates NMDA excitotoxicity in cerebral cortical neurons
- Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice
- Enhanced astrocytic Ca2+ signals contribute to neuronal excitotoxicity after status epilepticus
- Glutamate excitotoxicity and therapeutic targets for amyotrophic lateral sclerosis
- NMDA but not non-NMDA excitotoxicity is mediated by Poly (ADP-ribose) polymerase
- Excitatory amino acid antagonists protect cochlear auditory neurons from excitotoxicity
- Role of the JNK pathway in NMDA-mediated excitotoxicity of cortical neurons
- Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid β‐peptide toxicity in hippocampal neurons
- Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation
- Blocking excitotoxicity
- Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium …
- Prolonged glutamate excitotoxicity: effects on mitochondrial antioxidants and antioxidant enzymes
- excitotoxicity and motor neurone disease: a review of the evidence
- P2X7 receptor blockade prevents ATP excitotoxicity in oligodendrocytes and ameliorates experimental autoimmune encephalomyelitis
- excitotoxicity and mitochondria
- ALS-linked Cu/Zn–SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium …
- Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
- Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells
- Ascorbate transport by primary cultured neurons and its role in neuronal function and protection against excitotoxicity
- Novel treatment of excitotoxicity: targeted disruption of intracellular signalling from glutamate receptors
- The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of …
- Immunocytochemical characterization of quisqualic acid‐and N‐methyl‐D‐aspartate‐induced excitotoxicity in the retina of chicks
- Calbindin-D28K-containing neurons in animal models of neurodegeneration: possible protection from excitotoxicity
- Changes in intracellular pH associated with glutamate excitotoxicity
- Mechanisms underlying initiation of excitotoxicity associated with metabolic inhibition.
- Human spinal motoneurons express low relative abundance of GluR2 mRNA: an implication for excitotoxicity in ALS
- excitotoxicity in the enteric nervous system
- GluR2-dependent properties of AMPA receptors determine the selective vulnerability of motor neurons to excitotoxicity
- Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions
- Temporal lobe epilepsy caused by domoic acid intoxication: evidence for glutamate receptor–mediated excitotoxicity in humans
- Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine …
- Memantine: targeting glutamate excitotoxicity in Alzheimer’s disease and other dementias
- Reduced Progesterone Metabolites Protect Rat Hippocampal Neurones From Kainic Acid excitotoxicity In Vivo
- Cysteine-induced hypoglycemic brain damage: an alternative mechanism to excitotoxicity
- Mitochondrial control of acute glutamate excitotoxicity in cultured cerebellar granule cells
- AMPA and kainate receptors each mediate excitotoxicity in oligodendroglial cultures
- PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors
- Allostasis, allostatic load, and the aging nervous system: role of excitatory amino acids and excitotoxicity
- Spare respiratory capacity rather than oxidative stress regulates glutamate excitotoxicity after partial respiratory inhibition of mitochondrial complex I with rotenone
- Involvement of nitric oxide in kainic acid-induced excitotoxicity in rat brain
- Relationships between cerebrospinal fluid markers of excitotoxicity, ischemia, and oxidative damage after severe TBI: the impact of gender, age, and hypothermia
- Glutamate transporters and retinal excitotoxicity
- Necrosis and apoptosis after retinal ischemia: involvement of NMDA-mediated excitotoxicity and p53.
- The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis
- Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice
- Lithium induces brain-derived neurotrophic factor and activates TrkB in rodent cortical neurons: an essential step for neuroprotection against glutamate excitotoxicity
- Asiatic acid derivatives protect cultured cortical neurons from glutamate-induced excitotoxicity.
- Tumor necrosis factor α but not interleukin 1β mediates neuroprotection in response to acute nitric oxide excitotoxicity
- Experimental excitotoxicity provokes oxidative damage in mice brain and attenuation by extract of Asparagus racemosus
- Modulator effects of interleukin-1β and tumor necrosis factor-α on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures
- Slowly triggered excitotoxicity occurs by necrosis in cortical cultures
- Multiple classes of the oligodendrocyte lineage are highly vulnerable to excitotoxicity
- Neuroprotection by Δ9-tetrahydrocannabinol, the main active compound in marijuana, against ouabain-induced in vivo excitotoxicity
- Neural stem cells protect against glutamate-induced excitotoxicity and promote survival of injured motor neurons through the secretion of neurotrophic factors
- The actin-severing protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons
- Transgenic mice expressing a Huntington’s disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity
- Oxidative stress, mitochondrial function, and acute glutamate excitotoxicity in cultured cerebellar granule cells
- Mechanisms of excitotoxicity and Excitoprotection
- Direct Evidence That excitotoxicity in Cultured Neurons Is Mediated via N‐Methyl‐D‐Aspartate (NMDA) as well as Non‐NMDA Receptors
- Glia modulate the response of murine cortical neurons to excitotoxicity: glia exacerbate AMPA neurotoxicity
- Neuroprotection by melatonin from kainate‐induced excitotoxicity in rats
- Prostaglandin EP1 receptor contributes to excitotoxicity and focal ischemic brain damage
- Lithium suppresses excitotoxicity-induced striatal lesions in a rat model of Huntington’s disease
- Neurodegeneration in methylmalonic aciduria involves inhibition of complex II and the tricarboxylic acid cycle, and synergistically acting excitotoxicity
- α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionate (AMPA) receptors mediate excitotoxicity in the oligodendroglial lineage
- excitotoxicity induced by enhanced excitatory neurotransmission in cultured hippocampal pyramidal neurons
- A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cultures
- Δ9-Tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
- Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease
- … α-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity
- Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation …
- Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington’s disease
- Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term …
- Ebselen prevents noise-induced excitotoxicity and temporary threshold shift
- Prevention of excitotoxicity in primary retinal ganglion cells by (+)-pentazocine, a sigma receptor-1–specific ligand
- Neurotrophic effects of Cerebrolysin® in animal models of excitotoxicity
- Cortical neurons containing calretinin are selectively resistant to calcium overload and excitotoxicity in vitro
- excitotoxicity and neurological disorders: involvement of membrane phospholipids
- Dual modulation of endocannabinoid transport and fatty acid amide hydrolase protects against excitotoxicity
- Reply to: Glutamate excitotoxicity in glaucoma: throwing the baby out with the bathwater?
- The role of neuronal and endothelial nitric oxide synthase in retinal excitotoxicity.
- Chemokine CX3CL1 protects rat hippocampal neurons against glutamate-mediated excitotoxicity
- Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus
- Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases
- NMDA and glutamate evoke excitotoxicity at distinct cellular locations in rat cortical neurons in vitro
- The olivocerebellar projection mediates ibogaine-induced degeneration of Purkinje cells: a model of indirect, trans-synaptic excitotoxicity
- Regulation of proteins affecting NMDA receptor‐induced excitotoxicity in a Huntington’s mouse model
- Neuroprotective effects of ginsenoside Rg3 against homocysteine-induced excitotoxicity in rat hippocampus
- excitotoxicity and oxidative stress during inhibition of energy metabolism
- Ca2+ entry via AMPA/KA receptors and excitotoxicity in cultured cerebellar Purkinje cells
- Hypoxic damage to the periventricular white matter in neonatal brain: role of vascular endothelial growth factor, nitric oxide and excitotoxicity
- Neurolathyrism: mitochondrial dysfunction in excitotoxicity mediated by L-β-oxalyl aminoalanine
- Ischemic preconditioning ameliorates excitotoxicity by shifting glutamate/γ‐aminobutyric acid release and biosynthesis
- Blockade of calpain proteolytic activity rescues neurons from glutamate excitotoxicity
- The α7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca2+ dependent …
- Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity
- Blockade of glutamate excitotoxicity and its clinical applications
- Peroxisome-proliferator-activated receptor-gamma (PPARγ) activation protects neurons from NMDA excitotoxicity
- Selective estrogen receptor modulators protect hippocampal neurons from kainic acid excitotoxicity: differences with the effect of estradiol
- Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity
- Phenolic antioxidants attenuate hippocampal neuronal cell damage against kainic acid induced excitotoxicity
- Glutamate‐mediated excitotoxicity in neonatal hippocampal neurons is mediated by mGluR‐induced release of Ca++ from intracellular stores and is prevented by …
- Nitric oxide synthase isoforms undertake unique roles during excitotoxicity
- Zinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicity
- Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons
- excitotoxicity of L-dopa and 6-OH-dopa: implications for Parkinson’s and Huntington’s diseases
- Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective …
- Neuroprotective effects of eliprodil in retinal excitotoxicity and ischemia.
- TNFα-induced AMPA-receptor trafficking in CNS neurons; relevance to excitotoxicity?
- Mitochondrial membrane potential and the permeability transition in excitotoxicity
- Gangliosides prevent excitotoxicity through activation of TrkB receptor
- The contributions of excitotoxicity, glutathione depletion and DNA repair in chemically induced injury to neurones: exemplified with toxic effects on cerebellar granule …
- Acidotoxicity trumps excitotoxicity in ischemic brain
- Topical flunarizine reduces IOP and protects the retina against ischemia-excitotoxicity
- Role of glutamate receptor-mediated excitotoxicity in bilirubin-induced brain injury in the Gunn rat model
- Glutamate excitotoxicity in transient global cerebral ischemia
- Ethanol inhibits NMDA receptor‐mediated excitotoxicity in rat primary neuronal cultures
- Cerebrospinal fluid hypoxanthine, xanthine and uric acid levels may reflect glutamate-mediated excitotoxicity in different neurological diseases
- Ca2+ influx through AMPA or kainate receptors alone is sufficient to initiate excitotoxicity in cultured oligodendrocytes
- Glutamate excitotoxicity—a mechanism for axonal damage and oligodendrocyte death in multiple sclerosis?
- Peripheral markers of oxidative stress and excitotoxicity in neurodegenerative disorders: tools for diagnosis and therapy?
- excitotoxicity is required for induction of oxidative stress and apoptosis in mouse striatum by the mitochondrial toxin, 3-nitropropionic acid
- Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid
- Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons
- Ursolic acid protects hippocampal neurons against kainate-induced excitotoxicity in rats
- The biochemical mechanisms of the excitotoxicity of kainic acid
- Glutamate excitotoxicity: a mechanism of neurologic injury associated with hypothermic circulatory arrest
- Modulation of glutamate release and excitotoxicity by adenosine A2A receptors
- Effects of Volatile Anesthetics on N -methyl-d-aspartate excitotoxicity in Primary Rat Neuronal–Glial Cultures
- Protection against kainate-induced excitotoxicity by adenosine A2A receptor agonists and antagonists
- The effect of thiopental and propofol on NMDA-and AMPA-mediated glutamate excitotoxicity
- Allopregnanolone attenuates N-methyl-D-aspartate-induced excitotoxicity and apoptosis in the human NT2 cell line in culture
- excitotoxicity in the lung: N-methyl-D-aspartate-induced, nitric oxide-dependent, pulmonary edema is attenuated by vasoactive intestinal peptide and by inhibitors of …
- Interactions of excitatory neurotransmitters and xenobiotics in excitotoxicity and oxidative stress: glutamate and lead
- In Vivo excitotoxicity Induced by Ouabain, a Na+/K+-ATPase Inhibitor
- Activation of neuropeptide Y receptors is neuroprotective against excitotoxicity in organotypic hippocampal slice cultures
- Beneficial effects of rolipram in a quinolinic acid model of striatal excitotoxicity
- excitotoxicity in a chronic model of multiple sclerosis: Neuroprotective effects of cannabinoids through CB1 and CB2 receptor activation
- The exacerbation of hippocampal excitotoxicity by glucocorticoids is not mediated by apoptosis
- Acteoside and its aglycones protect primary cultures of rat cortical cells from glutamate-induced excitotoxicity
- Inhibition of nuclear factor κB is associated with neuroprotective effects of glycyrrhizic acid on glutamate-induced excitotoxicity in primary neurons
- Glycogen synthase kinase 3β inhibitor Chir025 reduces neuronal death resulting from oxygen-glucose deprivation, glutamate excitotoxicity, and cerebral ischemia
- An activity‐dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors
- Delayed antagonism of calpain reduces excitotoxicity in cultured neurons
- Pathophysiology of neonatal brain lesions: lessons from animal models of excitotoxicity
- Oligodendrocyte excitotoxicity determined by local glutamate accumulation and mitochondrial function
- Calcium green-5N, a novel fluorescent probe for monitoring high intracellular free Ca2+ concentrations associated with glutamate excitotoxicity in cultured rat brain …
- Lactate induced excitotoxicity in hippocampal slice cultures
- Increased adenosine in cerebrospinal fluid after severe traumatic brain injury in infants and children: association with severity of injury and excitotoxicity
- Hyperthermia and hypoxia increase tolerance of retinal ganglion cells to anoxia and excitotoxicity.
- Apnea promotes glutamate-induced excitotoxicity in hippocampal neurons
- Potential signalling pathways underlying corticotrophin‐releasing hormone‐mediated neuroprotection from excitotoxicity in rat hippocampus
- Calpain and N-methyl-d-aspartate (NMDA)-induced excitotoxicity in rat retinas
- Protection against hippocampal kainate excitotoxicity by intracerebral administration of an adenosine A2A receptor antagonist
- Development of N-methyl-D-aspartate excitotoxicity in cultured hippocampal neurons
- Rapid and reversible changes in dendrite morphology and synaptic efficacy following NMDA receptor activation: implication for a cellular defense against excitotoxicity
- A role for Na+‐dependent Ca2+ extrusion in protection against neuronal excitotoxicity
- excitotoxicity and ALS: what is unique about the AMPA receptors expressed on spinal motor neurons?
- Curcumin treatment protects rat retinal neurons against excitotoxicity: effect on N-methyl-D-aspartate-induced intracellular Ca2+ increase
- Carboxyl‐terminal fragment of Alzheimer’s APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity
- Plasminogen activators promote excitotoxicity‐induced retinal damage
- Sympathetic excitotoxicity in sepsis: pro-inflammatory priming of macrophages by norepinephrine
- Localization of glutamate receptors in developing cortical neurons in culture and relationship to susceptibility to excitotoxicity
- Brevetoxins cause acute excitotoxicity in primary cultures of rat cerebellar granule neurons
- Glutamate excitotoxicity and neuronal energy metabolism
- Neuroprotective potential of dietary restriction against kainate-induced excitotoxicity in adult male Wistar rats
- Apolipoprotein E protects against NMDA excitotoxicity
- Different receptors mediate motor neuron death induced by short and long exposures to excitotoxicity
- Proinflammatory cytokines and apoptosis following glutamate-induced excitotoxicity mediated by p38 MAPK in the hippocampus of neonatal rats
- Medroxyprogesterone acetate exacerbates glutamate excitotoxicity
- Protective effects of tetramethylpyrazine on kainate-induced excitotoxicity in hippocampal culture
- Microglial response to N‐methyl‐D‐aspartate‐mediated excitotoxicity in the immature rat brain
- Peroxynitrite and nitric oxide donors induce neuronal apoptosis by eliciting autocrine excitotoxicity
- Hippocampal Seizure Resistance and Reduced Neuronal excitotoxicity in Mice Lacking the Cav2.3 E/R-Type Voltage-Gated Calcium Channel
- Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors
- … of ionotropic glutamate receptor subunits on specific striatal neuron types and its implication for striatal vulnerability in glutamate receptor-mediated excitotoxicity
- Role of glutamate and excitotoxicity in neurologic diseases
- 17β-Estradiol reduces cortical lesion size in the glutamate excitotoxicity model by enhancing extracellular lactate: a new neuroprotective pathway
- excitotoxicity and bioenergetics in glutaryl‐CoA dehydrogenase deficiency
- Stimulation of prostaglandin EP2 receptors prevents NMDA-induced excitotoxicity
- Ethanol, stroke, brain damage, and excitotoxicity
- Glutamate excitotoxicity is involved in cell death caused by tributyltin in cultured rat cortical neurons
- DNA strand breaks induced by sustained glutamate excitotoxicity in primary neuronal cultures
- Protective effect of apolipoprotein E-mimetic peptides on N-methyl-D-aspartate excitotoxicity in primary rat neuronal–glial cell cultures
- Protection by eliprodil against excitotoxicity in cultured rat retinal ganglion cells.
- Excitatory amino acids in the developing brain: ontogeny, plasticity, and excitotoxicity
- Enhanced hippocampal neurodegeneration after traumatic or kainate excitotoxicity in GFAP-null mice
- excitotoxicity of quinolinic acid: modulation by endogenous antagonists
- Enzymatic degradation protects neurons from glutamate excitotoxicity
- The NMDA receptor/ion channel complex: a drug target for modulating synaptic plasticity and excitotoxicity
- … of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen–glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal …
- Chicken cerebellar granule neurons rapidly develop excitotoxicity in culture
- Long-term activation of adenosine A2a receptors blocks glutamate excitotoxicity in cultures of avian retinal neurons
- Selectively increased sensitivity of cerebellar granule cells to AMPA receptor-mediated excitotoxicity in a mouse model of Batten disease
- Differential c-Fos and caspase expression following kainic acid excitotoxicity
- Acute excitotoxicity in chick retina caused by the unusual amino acids BOAA and BMAA: effects of MK-801 and kynurenate
- excitotoxicity and dopaminergic dysfunction in the acquired immunodeficiency syndrome dementia complex: therapeutic implications
- AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity
- Lipopolysaccharide induces early tolerance to excitotoxicity via nitric oxide and cGMP
- Potassium channel activators abolish excitotoxicity in cultured hippocampal pyramidal neurons
- Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development
- The role of excitotoxicity and metabolic failure in the pathogenesis of neurological disorders.
- Neuroprotective potency of kynurenic acid against excitotoxicity
- Evaluation of the role of NMDA-mediated excitotoxicity in the selective neuronal loss in experimental Wernicke encephalopathy
- Blockade of cannabinoid CB1 receptor function protects against in vivo disseminating brain damage following NMDA‐induced excitotoxicity
- Delayed neurodegeneration and early astrogliosis after excitotoxicity to the aged brain
- Calretinin and calbindin D-28k, but not parvalbumin protect against glutamate-induced delayed excitotoxicity in transfected N18–RE 105 neuroblastoma–retina hybrid …
- Hypoxia, excitotoxicity, and neuroprotection in the hippocampal slice preparation
- Relative resistance of striatal neurons containing calbindin or parvalbumin to quinolinic acid-mediated excitotoxicity compared to other striatal neuron types
- Differential effects of BDNF, ADNF9, and TNFα on levels of NMDA receptor subunits, calcium homeostasis, and neuronal vulnerability to excitotoxicity
- In vivo neuroprotective role of NMDA receptors against kainate‐induced excitotoxicity in murine hippocampal pyramidal neurons
- Neuroprotective Effects of Thymosin β4 in Experimental Models of excitotoxicity
- Excitatory amino acid receptors, excitotoxicity, and the human nervous system.
- Brevetoxin‐Induced Autocrine excitotoxicity Is Associated with Manifold Routes of Ca2+ Influx
- Ability of GDNF to diminish free radical production leads to protection against kainate‐induced excitotoxicity in hippocampus
- Calcium mediated excitotoxicity in neurofilament aggregate-bearing neurons in vitro is NMDA receptor dependant
- Growth factors and gangliosides as neuroprotective agents in excitotoxicity and ischemia
- Nitric oxide inhibitors attenuate N-methyl-D-aspartate excitotoxicity in rat hippocampal slices
- Cyclosporin A targets involved in protection against glutamate excitotoxicity
- AMPA protects cultured neurons against glutamate excitotoxicity through a phosphatidylinositol 3‐kinase‐dependent activation in extracellular signal‐regulated …
- Neuroprotection of striatal neurons against kainate excitotoxicity by neurotrophins and GDNF family members
- Emergence of excitotoxicity in cultured forebrain neurons coincides with larger glutamate-stimulated [Ca2+] i increases and NMDA receptor mRNA levels
- Interferon‐γ is up‐regulated in the hippocampus in response to intermittent fasting and protects hippocampal neurons against excitotoxicity
- The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo
- Prevention of in vivo excitotoxicity by a family of trialkylglycines, a novel class of neuroprotectants
- Acetylcholine protection of adult pig retinal ganglion cells from glutamate-induced excitotoxicity
- Protein-protein coupling/uncoupling enables dopamine D2 receptor regulation of AMPA receptor-mediated excitotoxicity
- Novel neuroprotective mechanisms of pramipexole, an anti-Parkinson drug, against endogenous dopamine-mediated excitotoxicity
- Enhanced cell death in MeCP2 null cerebellar granule neurons exposed to excitotoxicity and hypoxia
- excitotoxicity‐related endocytosis in cortical neurons
- Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression: a prominent role in neuroprotection against excitotoxicity
- TGFβ trophic factors differentially modulate motor axon outgrowth and protection from excitotoxicity
- … membrane potential and increased mitochondrial reactive oxygen species production correlate with age‐related glutamate excitotoxicity in rat hippocampal neurons
- Ergothioneine treatment protects neurons against N-methyl-D-aspartate excitotoxicity in an in vivo rat retinal model
- Genetic basis of kainate-induced excitotoxicity in mice: phenotypic modulation of seizure-induced cell death
- An ex vivo rat retinal preparation for excitotoxicity studies
- excitotoxicity and N‐methyl‐D‐Aspartate receptors
- N‐methyl‐D‐aspartate and TrkB receptors protect neurons against glutamate excitotoxicity through an extracellular signal‐regulated kinase pathway
- Potentiation of excitotoxicity in HIV-1-associated dementia and the significance of glutaminase
- A novel organotypic culture model of the postnatal mouse retina allows the study of glutamate-mediated excitotoxicity
- Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity
- Adeno-associated viruses containing bFGF or BDNF are neuroprotective against excitotoxicity
- Oxidative stress in anticholinesterase-induced excitotoxicity
- Potentiation by histamine of synaptically mediated excitotoxicity in cultured hippocampal neurones: a possible role for mast cells
- excitotoxicity, energy metabolism and neurodegeneration
- Downregulation of glutaredoxin but not glutathione loss leads to mitochondrial dysfunction in female mice CNS: implications in excitotoxicity
- mGluR7‐like metabotropic glutamate receptors inhibit NMDA‐mediated excitotoxicity in cultured mouse cerebellar granule neurons
- Basic fibroblast growth factor protects against excitotoxicity and chemical hypoxia in both neonatal and adult rats
- Glutamate excitotoxicity attenuates insulin-like growth factor-I prosurvival signaling
- Neuronal death and tumor necrosis factor-α response to glutamate-induced excitotoxicity in the cerebral cortex of neonatal rats
- The role of neurotransporters in excitotoxicity, neuronal cell death, and other neurodegenerative processes
- Nitric oxide in cerebral ischemic neurodegeneration and excitotoxicity
- Acute neuroinflammation exacerbates excitotoxicity in rat hippocampus in vivo
- Melatonin protects primary cultures of cerebellar granule neurons from kainate but not from N-methyl-D-aspartate excitotoxicity
- Neuropeptide Y expression in mouse hippocampus and its role in neuronal excitotoxicity1
- Taxol stabilizes [Ca2+] i and protects hippocampal neurons against excitotoxicity
- Recovery of structure and function of inner ear afferent synapses following kainic acid excitotoxicity
- excitotoxicity mediated by non‐NMDA receptors causes distal axonopathy in long‐term cultured spinal motor neurons
- GABAA Receptor Activation Attenuates excitotoxicity but Exacerbates Oxygen—Glucose Deprivation-Induced Neuronal Injury In Vitro
- Cyclic AMP‐elevating agents prevent oligodendroglial excitotoxicity
- Is zinc the link between compromises of brain perfusion (excitotoxicity) and Alzheimer’s disease?
- The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A …
- … inhibition of Src tyrosine kinase in rat cerebral cortical neurons: a role in neuroprotection against N-methyl-D-aspartate receptor-mediated excitotoxicity
- N-methyl-D-aspartate excitotoxicity: relationships among plasma membrane potential, Na+/Ca2+ exchange, mitochondrial Ca2+ overload, and cytoplasmic …
- Dietary restriction differentially protects from neurodegeneration in animal models of excitotoxicity
- Effects of puerarin against glutamate excitotoxicity on cultured mouse cerebral cortical neurons.
- Glutamate excitotoxicity in glaucoma: truth or fiction?
- In vitro and in vivo protection against kainate‐induced excitotoxicity by melatonin
- Melatonin protects primary cultures of rat cortical neurones from NMDA excitotoxicity and hypoxia/reoxygenation
- Platelet activating factor receptor expression is associated with neuronal apoptosis in an in vivo model of excitotoxicity
- Neuronal bioenergetic defects, excitotoxicity and Alzheimer’s disease:“Use it and lose it”
- Rabies virus infection of primary neuronal cultures and adult mice: failure to demonstrate evidence of excitotoxicity
- 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect cortical neurons from excitotoxicity
- Synergistic versus antagonistic actions of glutamate and glutathione: the role of excitotoxicity and oxidative stress in neuronal disease.
- Dopaminergic modulation of early signs of excitotoxicity in visualized rat neostriatal neurons
- … nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainate-induced excitotoxicity
- Differential vulnerability of hippocampus, basal ganglia, and prefrontal cortex to long-term NMDA excitotoxicity
- Strain-dependent differences in calcium signaling predict excitotoxicity in murine hippocampal neurons
- A behavioral model of excitotoxicity: retinal degeneration, loss of vision, and subsequent recovery after intraocular NMDA administration in adult rats
- Acamprosate is neuroprotective against glutamate‐induced excitotoxicity when enhanced by ethanol withdrawal in neocortical cultures of fetal rat brain
- HIV‐1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity
- Slow and selective death of spinal motor neurons in vivo by intrathecal infusion of kainic acid: implications for AMPA receptor‐mediated excitotoxicity in ALS
- Developmental expression, compartmentalization, and possible role in excitotoxicity of a putative NMDA receptor protein in cultured hippocampal neurons
- The intact isolated (ex vivo) retina as a model system for the study of excitotoxicity
- Neuroprotection against NMDA excitotoxicity by group I metabotropic glutamate receptors is associated with reduction of NMDA stimulated currents
- Reversible and irreversible damage to cochlear afferent neurons by kainic acid excitotoxicity
- Glutamate receptors and excitotoxicity.
- NMDA and AMPA receptor expression and cortical neuronal death are associated with p38 in glutamate‐induced excitotoxicity in vivo
- The role of group I metabotropic glutamate receptors in neuronal excitotoxicity in Alzheimer’s disease
- The role of apoptosis and excitotoxicity in the death of spinal motoneurons and interneurons after neonatal nerve injury
- Evidence that actin depolymerization protects hippocampal neurons against excitotoxicity by stabilizing [Ca2+] i
- N-methyl-D-aspartate-induced excitotoxicity in adult rat retina is antagonized by single systemic injection of MK-801
- l‐(−)‐Desmethylselegiline, a Metabolite of Selegiline [l‐(−)‐Deprenyl], Protects Mesencephalic Dopamine Neurons from excitotoxicity In Vitro
- Chronic treatment with glutaric acid induces partial tolerance to excitotoxicity in neuronal cultures from chick embryo telencephalons
- Differential contribution of plasmalemmal Na+/Ca2+ exchange isoforms to sodium‐dependent calcium influx and NMDA excitotoxicity in depolarized neurons
- Neuroprotection of adenoviral-vector-mediated GDNF expression against kainic-acid-induced excitotoxicity in the rat hippocampus
- excitotoxicity in Huntington disease
- AMPA‐mediated excitotoxicity in oligodendrocytes: role for Na+–K+–Cl− co‐transport and reversal of Na+/Ca2+ exchanger
- excitotoxicity in the embryonic chick spinal cord
- Differential effects of NMDA–receptor antagonists on long-term potentiation and hypoxic/hypoglycaemic excitotoxicity in hippocampal slices
- The Guam cycad toxin methylazoxymethanol damages neuronal DNA and modulates tau mRNA expression and excitotoxicity
- Kainate excitotoxicity in organotypic hippocampal slice cultures: evidence for multiple apoptotic pathways
- Homocysteic and homocysteine sulphinic acid exhibit excitotoxicity in organotypic cultures from rat brain
- Evidence of excitotoxicity in the brain of the ornithine carbamoyltransferase deficient sparse fur mouse
- 1-Methyl-4-phenylpyridinium induces autocrine excitotoxicity, protease activation, and neuronal apoptosis
- Ability of retinal Müller glial cells to protect neurons against excitotoxicity in vitro depends upon maturation and neuron‐glial interactions
- Basic fibroblast growth factor protects striatal neurons in vitro from NMDA-receptor mediated excitotoxicity
- Poly (ADP-ribose) polymerase as a key player in excitotoxicity and post-ischemic brain damage
- Pharmacological properties of acquired excitotoxicity in Chinese hamster ovary cells transfected with N-methyl-D-aspartate receptor subunits.
- Involvement of superoxide in excitotoxicity and DNA fragmentation in striatal vulnerability in mice after treatment with the mitochondrial toxin, 3-nitropropionic acid
- alpha-Phenyl-N-tert-butylnitrone attenuates excitotoxicity in rat striatum by preventing hydroxyl radical accumulation
- Acetylcholine neuroprotection against glutamate-induced excitotoxicity in adult pig retinal ganglion cells is partially mediated through α4 nAChRs
- excitotoxicity in the brain
- Basal ganglia calcification induced by excitotoxicity: an experimental model characterised by electron microscopy and X-ray microanalysis
- Secondary excitotoxicity contributes to dopamine-induced apoptosis of dopaminergic neuronal cultures
- Antiparkinsonian drugs and in vitro excitotoxicity
- Susceptibility of cerebellar granule neurons from GM2/GD2 synthase-null mice to apoptosis induced by glutamate excitotoxicity and elevated KCl: rescue by GM1 and …
- Ethanol inhibits excitotoxicity in cerebral cortical cultures
- Chronic excitotoxicity in the guinea pig cochlea induces temporary functional deficits without disrupting otoacoustic emissions
- Modulation of NMDA‐mediated excitotoxicity by protein kinase C
- Maturation of vulnerability to excitotoxicity: intracellular mechanisms in cultured postnatal hippocampal neurons
- … 2+‐dependent generation of mitochondrial reactive oxygen species serves as a signal for poly(ADP‐ribose) polymerase‐1 activation during glutamate excitotoxicity
- Protection of cortical cells by equine estrogens against glutamate-induced excitotoxicity is mediated through a calcium independent mechanism
- Genetic evidence for adenylyl cyclase 1 as a target for preventing neuronal excitotoxicity mediated by N-methyl-D-aspartate receptors
- Regulation of c‐Jun N‐terminal kinase, p38 kinase and AP‐1 DNA binding in cultured brain neurons: roles in glutamate excitotoxicity and lithium neuroprotection
- … enhances endogenous extracellular glutamate levels in primary cultures of rat cortical neurons: involvement of neurotensin receptor in NMDA induced excitotoxicity
- Protective effect of methanol extract of Uncaria rhynchophylla against excitotoxicity induced by N-methyl-D-aspartate in rat hippocampus
- 9. excitotoxicity and epileptic brain damage
- Effects of IL6 and IL1β on aFGF expression and excitotoxicity in NT2N cells
- Mechanisms of neuronal apoptosis and excitotoxicity
- Ivermectin inhibits AMPA receptor-mediated excitotoxicity in cultured motor neurons and extends the life span of a transgenic mouse model of amyotrophic lateral …
- Decreased epileptic susceptibility correlates with neuropeptide Y overexpression in a model of tolerance to excitotoxicity
- Intracellular calcium and magnesium: critical determinants of excitotoxicity?
- NMDA receptor overstimulation triggers a prolonged wave of immediate early gene expression: relationship to excitotoxicity
- N-methyl-D-aspartate-induced excitotoxicity causes myopia in hatched chicks.
- excitotoxicity and neuroprotection
- Dopaminergic modulation of excitotoxicity in rat striatum: evidence from nigrostriatal lesions
- Lysosomal enzyme cathepsin B is involved in kainic acid-induced excitotoxicity in rat striatum
- … , phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates following quinolinic acid excitotoxicity in the rat
- Exacerbation of NMDA, AMPA, and l‐Glutamate excitotoxicity by the Succinate Dehydrogenase Inhibitor Malonate
- Why do many NMDA antagonists fail, while others are safe and effective at blocking excitotoxicity associated with dementia and acute injury?
- Free radicals and mitochondria dysfunction in excitotoxicity and neurodegenerative disease
- Neuroprotectins A and B, bicyclohexapeptides protecting chick telencephalic neuronal cells from excitotoxicity I. Fermentation, isolation, physico-chemical properties …
- Susceptibility of retinal ganglion cells to excitotoxicity depends on soma size and retinal eccentricity
- Haloperidol induces neurotoxicity by the NMDA receptor downstream signaling pathway, alternative from glutamate excitotoxicity
- c-fos mRNA Expression in Rat Cortical Neurons During Glutamate-Mediated excitotoxicity
- Heterogeneity between hippocampal and septal astroglia as a contributing factor to differential in vivo AMPA excitotoxicity
- Dearth of glutamate transporters contributes to striatal excitotoxicity
- Phenformin suppresses calcium responses to glutamate and protects hippocampal neurons against excitotoxicity
- Intrastriatal grafting of a GDNF‐producing cell line protects striatonigral neurons from quinolinic acid excitotoxicity in vivo
- Sequential expression of surface antigens and transcription factor NFκB by hippocampal cells in excitotoxicity and experimental epilepsy
- Selective activation of group II mGluRs with LY354740 does not prevent neuronal excitotoxicity
- … transport alteration triggers differentiation‐state selective oxidative death of cultured astrocytes: a mechanism different from excitotoxicity depending on intracellular …
- Glutamate-induced excitotoxicity in retina: neuroprotection with receptor antagonist, dextromethorphan, but not with calcium channel blockers
- Vulnerability of the hippocampus to kainate excitotoxicity in the aged, mature and young adult rat
- Neuroprotection by melatonin from glutamate‐induced excitotoxicity during development of the cerebellum in the chick embryo
- Evidence disputing the importance of excitotoxicity in hippocampal neuron death after experimental traumatic brain injury
- Reduction of excitotoxicity and associated leukocyte recruitment by a broad‐spectrum matrix metalloproteinase inhibitor
- The dual role of prostaglandin E2 in excitotoxicity and preconditioning-induced neuroprotection
- Erratum to “Roles of phospholipases A2 in brain cell and tissue injury associated with ischemia and excitotoxicity”[J. Lip. Med. Cell Signal. 14 (1996) 15]
- GDNF and neublastin protect against NMDA-induced excitotoxicity in hippocampal slice cultures
- Electrophysiological mechanisms of delayed excitotoxicity: positive feedback loop between NMDA receptor current and depolarization-mediated glutamate release
- The excitotoxicity theory of glaucoma
- Excitatory amino acid neurotransmission, excitotoxicity and excitotoxins.
- Depolarization of mitochondria in isolated CA1 neurons during hypoxia, glucose deprivation and glutamate excitotoxicity
- Roles of phospholipases A2 in brain cell and tissue injury associated with ischemia and excitotoxicity
- Parvalbumin-containing interneurons in rat hippocampus have an AMPA receptor profile suggestive of vulnerability to excitotoxicity
- Hypothermia, metabolic stress, and NMDA‐mediated excitotoxicity
- Ro5‐4864, a peripheral benzodiazepine receptor ligand, reduces reactive gliosis and protects hippocampal hilar neurons from kainic acid excitotoxicity
- Diltiazem-induced neuroprotection in glutamate excitotoxicity and ischemic insult of retinal neurons
- Failure of neuronal ion exchange, not potentiated excitation, causes excitotoxicity after inhibition of oxidative phosphorylation
- … glucose‐deprived neurons, Na+ influx reverses plasmalemmal K+‐dependent and K+‐independent Na+/Ca2+ exchangers and contributes to NMDA excitotoxicity
- Metabotropic glutamate receptor modulation of excitotoxicity in the neostriatum: role of calcium channels
- Hippocampal alterations of apolipoprotein E and D mRNA levels in vivo and in vitro following kainate excitotoxicity
- The effects of excitotoxicity on the expression of the amyloid precursor protein gene in the brain and its modulation by neuroprotective agents
- Recovery of kainic acid excitotoxicity in chinchilla cochlea
- Role of cyclooxygenase-2 in neuronal cell cycle activity and glutamate-mediated excitotoxicity
- excitotoxicity mediated by Ca 2+-permeable GluR4-containing AMPA receptors involves the AP-1 transcription factor
- Activation of multiple metabotropic glutamate receptor subtypes prevents NMDA‐induced excitotoxicity in rat hippocampal slices
- Roles of phospholipases A2 in brain cell and tissue injury associated with ischemia and excitotoxicity.
- Manipulation of membrane potential modulates malonate‐induced striatal excitotoxicity in vivo
- Schwann cells exhibit excitotoxicity consistent with release of NMDA receptor agonists
- In vitro hypoxia and excitotoxicity in human brain induce calcineurin–Bcl-2 interactions
- Characterization of neuroprotection from excitotoxicity by moderate and profound hypothermia in cultured cortical neurons unmasks a temperature-insensitive …
- excitotoxicity and plasticity of IHC-auditory nerve contributes to both temporary and permanent threshold shift
- Induction of neurosteroid synthesis by NMDA receptors in isolated rat retina: a potential early event in excitotoxicity
- Astroglial alterations in amyotrophic lateral sclerosis (ALS) model of slow glutamate excitotoxicity in vitro.
- Involvement of the Snk-SPAR pathway in glutamate-induced excitotoxicity in cultured hippocampal neurons
- Dopamine–glutamate interactions in the striatum: behaviourally relevant modification of excitotoxicity by dopamine receptor-mediated mechanisms
- Suppression of murine cerebral F2-isoprostanes and F4-neuroprostanes from excitotoxicity and innate immune response in vivo by α-or γ-tocopherol
- Glutamate excitotoxicity in glaucoma: truth or fiction? By AJ Lotery
- Excitatory receptors and their role in excitotoxicity
- The effect of gp130 stimulation on glutamate-induced excitotoxicity in primary hippocampal neurons
- Heme oxygenase-1 protects brain from acute excitotoxicity
- Instrumental role of Na+ in NMDA excitotoxicity in glucose‐deprived and depolarized cerebellar granule cells
- Interleukin-1β exacerbates hypoxia-induced neuronal damage, but attenuates toxicity produced by simulated ischaemia and excitotoxicity in rat organotypic …
- Tachykinins protect cholinergic neurons from quinolinic acid excitotoxicity in striatal cultures
- Phosphoinositide second messengers in cholinergic excitotoxicity.
- NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization
- Nuclear disintegration as a leading step of glutamate excitotoxicity in brain neurons
- Roscovitine triggers excitotoxicity in cultured granule neurons by enhancing glutamate release
- β‐Amyloid excitotoxicity in Rat Magnocellular Nucleus Basalis: Effect of Cortical Deafferentation on Cerebral Blood Flow Regulation and Implications for Alzheimer’s …
- Blockade of desensitization augments quisqualate excitotoxicity in hippocampal neurons
- Fimbria–fornix transection and excitotoxicity produce similar neurodegeneration in the septum
- The Competitive Transport Inhibitor L‐trans‐pyrrolidine‐2,4‐dicarboxylate Triggers excitotoxicity in Rat Cortical Neuron‐Astrocyte Co‐cultures via Glutamate Release …
- Ethanol pretreatment enhances NMDA excitotoxicity in biogenic amine neurons: protection by brain derived neurotrophic factor
- Nuclear magnetic resonance imaging measurements of water diffusion in the perfused hippocampal slice during N-methyl-D-aspartate-induced excitotoxicity
- Neurotrophic factor mediated protection from excitotoxicity and disturbances in calcium and free radical metabolism
- Astrocytes regulate N-methyl-D-aspartate receptor subunit composition increasing neuronal sensitivity to excitotoxicity
- AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization.
- excitotoxicity of NMDA and kainic acid is modulated by nigrostriatal dopaminergic fibres
- Role of endonuclease G in neuronal excitotoxicity in mice
- NMDA-evoked excitotoxicity increases tissue transglutaminase in cerebellar granule cells
- Bilobalide, a component of the Ginkgo biloba extract (EGb 761), protects against neuronal death in global brain ischemia and in glutamate-induced excitotoxicity.
- Lubeluzole protects hippocampal neurons from excitotoxicity in vitro and reduces brain damage caused by ischemia
- GM1 and NGF modulate Ca2+ homeostasis and GAP43 mRNA expression in cultured dorsal root ganglion neurons with excitotoxicity induced by glutamate
- Targeting PDZ domain proteins for treating NMDA receptor-mediated excitotoxicity
- Neuroprotectins A and B, Bicyclohexapeptides Protecting Chick Telencephalic Neurons from excitotoxicity
- NMDA excitotoxicity and free radical generation in rat brain homogenates: application of a chemiluminescence assay
- Contributing mechanisms for cysteine excitotoxicity in cultured cerebellar granule cells
- The effects of artificial calcium buffers on calcium responses and glutamate-mediated excitotoxicity in cultured hippocampal neurons
- NMDA receptor-mediated excitotoxicity contributes to the cerebral hypoxic injury of a rat model of posthypoxic myoclonus
- DNA damage and nonhomologous end joining in excitotoxicity: Neuroprotective role of DNA‐PKcs in kainic acid‐induced seizures
- … ‐specific repression of calpain expression and calpain enzymatic activity in neuronal cells – implications for neuroprotection against Ca2+‐mediated excitotoxicity
- An experimental model combining microdialysis with electrophysiology, histology, and neurochemistry for studying excitotoxicity in spinal cord injury
- The selective AMPA receptor antagonist GYKI 53784 blocks action potential generation and excitotoxicity in the guinea pig cochlea
- Amyotrophic lateral sclerosis, excitotoxicity and riluzole
- Evaluation of drugs acting at glutamate transporters in organotypic hippocampal cultures: new evidence on substrates and blockers in excitotoxicity
- Nitric oxide in retina: relation to excitatory amino acids and excitotoxicity
- Brain‐derived neurotrophic factor prevents changes in Bcl‐2 family members and caspase‐3 activation induced by excitotoxicity in the striatum
- Release and uptake of glutamate as related to excitotoxicity.
- Prevention of glutamate excitotoxicity in motor neurons by 5, 6-dihydrocyclopenta-1, 2-dithiole-3-thione: implication to the development of neuroprotective drugs
- excitotoxicity, apoptosis, and ischemic stroke
- Effect of ebselen and organochalcogenides on excitotoxicity induced by glutamate in isolated chick retina
- Peroxiredoxin 2 overexpression protects cortical neuronal cultures from ischemic and oxidative injury but not glutamate excitotoxicity, whereas Cu/Zn superoxide …
- Glial‐derived arginine, the nitric oxide precursor, protects neurons from NMDA‐induced excitotoxicity
- Cyclic GMP/cyclic GMP‐dependent protein kinase system prevents excitotoxicity in an immortalized oligodendroglial cell line
- Neurotensin enhances glutamate excitotoxicity in mesencephalic neurons in primary culture
- Subchronic intraventricular infusion of quinolinic acid produces working memory impairment—a model of progressive excitotoxicity
- Kainic acid—induced excitotoxicity is associated with a complex c‐Fos and c‐Jun response which does not preclude either cell death or survival
- Quinolinic Acid Accumulation During Neuroinflammation: Does it Imply excitotoxicity?
- Cholesterol deficiency increases the vulnerability of hippocampal glia in primary culture to glutamate-induced excitotoxicity
- In vivo assessment of kynurenate neuroprotective potency and quinolinate excitotoxicity
- Short‐term effects of kainic acid on CA1 hippocampal interneurons differentially vulnerable to excitotoxicity
- Rat cerebellar granule cells are protected from glutamate-induced excitotoxicity by S-nitrosoglutathione but not glutathione
- Neuroprotective effects of lamotrigine and remacemide on excitotoxicity induced by glutamate agonists in isolated chick retina
- Intrinsic redox properties of N-methyl-D-aspartate receptor can determine the developmental expression of excitotoxicity in rat cortical neurons in vitro
- Cortical and striatal neuronal cultures of the same embryonic origin show intrinsic differences in glutamate receptor expression and vulnerability to excitotoxicity
- Effects of calcium chelators on intracellular calcium and excitotoxicity
- Pregnenolone sulfate modulates NMDA receptors, inducing and potentiating acute excitotoxicity in isolated retina
- Mechanisms of VIP‐induced neuroprotection against neonatal excitotoxicity
- The mode of spinal motor neurons degeneration in a model of slow glutamate excitotoxicity in vitro.
- The influence of glutamate receptor 2 expression on excitotoxicity in Glur2 null mutant mice
- … of 1, 2, 3, 4‐tetrahydroisoquinolines neuroprotection: the importance of free radicals scavenging properties and inhibition of glutamate‐induced excitotoxicity
- Transcriptional pharmacology of neurodegenerative disorders: novel venue towards neuroprotection against excitotoxicity?
- Substance P containing polymer implants protect against striatal excitotoxicity
- Aldolase C‐positive cerebellar Purkinje cells are resistant to delayed death after cerebral trauma and AMPA‐mediated excitotoxicity
- excitotoxicity
- Kainic acid-induced excitotoxicity in neurons and glial cells
- Glutamate-related excitotoxicity neuroprotection with memantine, an uncompetitive antagonist of NMDA-glutamate receptor, in Alzheimer’s disease and vascular …
- Hypoxia in presence of blockers of excitotoxicity induces a caspase-dependent neuronal necrosis
- Insulin-specific sensitization of cultured cerebrocortical neurons to glutamate excitotoxicity
- excitotoxicity and neuropsychiatric disorders
- HSV-mediated delivery of virally derived anti-apoptotic genes protects the rat hippocampus from damage following excitotoxicity, but not metabolic disruption
- Use of a multiwell fluorescence scanner with propidium iodide to assess NMDA mediated excitotoxicity in rat cortical neuronal cultures
- [3H]L-NG-Nitroarginine Binding after Transient Focal Ischemia and NMDA-Induced excitotoxicity in Type I and Type III Nitric Oxide Synthase Null Mice
- Association of c‐fos mRNA expression and excitotoxicity in primary cultures of mouse neocortical and cerebellar neurons
- A sublethal dose of TNFα potentiates kainate-induced excitotoxicity in optic nerve oligodendrocytes
- Lentiviral-mediated delivery of Bcl-2 or GDNF protects against excitotoxicity in the rat hippocampus
- Ca 2+ and Na+ dependence of 3-hydroxyglutarate-induced excitotoxicity in primary neuronal cultures from chick embryo telencephalons
- excitotoxicity plays a role in the death of tyrosine hydroxylase-immunopositive nigral neurons cultured in serum-free medium
- excitotoxicity affects membrane potential and calmodulin kinase II activity in cultured rat cortical neurons.
- Improvements in an in-vitro assay for excitotoxicity by measurement of early gene (c-fos mRNA) levels
- excitotoxicity in neurological diseases: New therapeutic challenge
- Aurintricarboxylic acid protects hippocampal neurons from glutamate excitotoxicity in vitro
- T-cells and excitotoxicity
- Kainate excitotoxicity is mediated by AMPA-but not kainate-preferring receptors in embryonic rat hippocampal cultures
- AMPA receptor‐mediated excitotoxicity in human NT2‐N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+
- Caspase-3-mediated cleavage of PHF-1 tau during apoptosis irrespective of excitotoxicity and oxidative stress: an implication to Alzheimer’s disease
- Peptide growth factors but not ganglioside protect against excitotoxicity in rat retinal neurons in vitro
- Parathyroid hormone-related protein protects against kainic acid excitotoxicity in rat cerebellar granule cells by regulating L-type channel calcium flux
- Lithium protection from glutamate excitotoxicity: therapeutic implications
- excitotoxicity and neuroprotection
- Vascular changes in the spinal cord in N-methyl-D-aspartate-induced excitotoxicity: morphological and permeability studies
- Caspase-3 activation and DNA fragmentation in primary hippocampal neurons following glutamate excitotoxicity
- Effects of Ginkgo biloba extract against excitotoxicity induced by NMDA receptors and mechanism thereof
- Polyamine metabolism and glutamate receptor agonists‐mediated excitotoxicity in the rat brain
- In vivo studies on the protective role of minocycline against excitotoxicity caused by malonate or N-methyl-D-aspartate
- excitotoxicity at Both NMDA and Non‐NMDA Glutamate Receptors Is Antagonized by Aurintricarboxylic Acid: Evidence for Differing Mechanisms of Action
- Real-time imaging of intrinsic optical signals during early excitotoxicity evoked by domoic acid in the rat hippocampal slice
- Glycine-induced CA1 excitotoxicity in the rat hippocampal slice
- Nerve growth factor and basic fibroblast growth factor protect cholinergic neurons against quinolinic acid excitotoxicity in rat neostriatum
- Na+/H+ Exchanger Inhibitor, SM-20220, Is Protective Against excitotoxicity in Cultured Cortical Neurons
- Presenilin-1 regulates the neuronal threshold to excitotoxicity both physiologically and pathologically
- Postnatal treatment with ACTH-(4-9) analog ORG 2766 attenuates N-methyl-D-aspartate-induced excitotoxicity in rat nucleus basalis in adulthood
- ■ REVIEW: excitotoxicity, Free Radicals, Necrosis, and Apoptosis
- Intracellular Survival Pathways against Glutamate Receptor Agonist excitotoxicity in Cultured Neurons: Intracellular Calcium Responsesa
- Erythropoietin is neuroprotective on GABAergic neurons against kainic acid-excitotoxicity in the rat spinal cell cultures
- Metabotropic and ionotropic transducers of glutamate signal inversely control cytoplasmic Ca2+ concentration and excitotoxicity in cultured cerebellar granule …
- 17β-Estradiol effect on the extracellular concentration of amino acids in the glutamate excitotoxicity model in the rat
- Action of the anti-ischemic agent ifenprodil onn-methyl-D-aspartate and kainate-mediated excitotoxicity
- Ethanol and excitotoxicity in Cultured Cortical Neurons: Differential Sensitivity of N‐Methyl‐D‐Aspartate and Sodium Nitroprusside Toxicity
- Aurintricarboxylic acid prevents NMDA‐mediated excitotoxicity: evidence for its action as an NMDA receptor antagonist
- Infection with adeno-associated virus may protect against excitotoxicity
- Normal sensitivity to excitotoxicity in a transgenic Huntington’s disease rat
- Transforming growth factor α‐induced expression of type‐1 plasminogen activator inhibitor in astrocytes rescues neurons from excitotoxicity
- Selectively increasing inducible heat shock protein 70 via TAT‐protein transduction protects neurons from nitrosative stress and excitotoxicity
- Heat shock protein HSP70 increases the resistance of cortical cells to glutamate excitotoxicity
- Oxidative stress during energy impairment in mesencephalic cultures is not a downstream consequence of a secondary excitotoxicity
- Tyrosine phosphatase SHP‐2 is a mediator of activity‐dependent neuronal excitotoxicity
- Group I metabotropic glutamate receptor inhibition selectively blocks a prolonged Ca2+ elevation associated with age-dependent excitotoxicity
- Nuclear translocation of extracellular signal-regulated kinases in neuronal excitotoxicity
- Neuronal TGF-β1 mediates IL-9/mast cell interaction and exacerbates excitotoxicity in newborn mice
- Short-term consequences of N-methyl-D-aspartate excitotoxicity in rat magnocellular nucleus basalis: effects on in vivo labelling of cholinergic neurons
- Diminished calcium homeostasis and increased susceptibility to excitotoxicity of JS 3/16 progenitor cells after differentiation to oligodendroglia
- The antioxidant cocktail, effective microorganism X (EM-X), protects retinal neurons in rats against N-methyl-D-aspartate excitotoxicity in vivo
- … factor, neurotrophin-3 and neurotrophin-4/5 differentially regulate the phenotype and prevent degenerative changes in striatal projection neurons after excitotoxicity in …
- Accumulation of quinolinic acid with neuroinflammation: does it mean excitotoxicity?
- GM1 ganglioside administration protects spinal neurons after glutamate excitotoxicity
- Role of polyamine metabolism in kainic acid excitotoxicity in organotypic hippocampal slice cultures
- Glycogen synthase kinase-3 inhibitors protect central neurons against excitotoxicity
- ω-Agatoxin IVA and excitotoxicity in cortical neuronal cultures
- Neuroprotection against excitotoxicity by N-alkylglycines in rat hippocampal neurons
- Apoptosis is not enhanced in primary mixed neuronal/glial cultures protected by isoflurane against N-methyl-D-aspartate excitotoxicity
- Radiation-induced apoptosis in developing rats and kainic acid-induced excitotoxicity in adult rats are associated with distinctive morphological and biochemical c-Jun …
- Differential vulnerability of autonomic and somatic motor neurons to N-methyl-D-aspartate-induced excitotoxicity
- Propionyl-IIGL tetrapeptide antagonizes β-amyloid excitotoxicity in rat nucleus basalis
- … 3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit composition and cAMP-response element-binding protein regulate oligodendrocyte excitotoxicity
- TrkB and TrkC are differentially regulated by excitotoxicity during development of the basal ganglia
- Postlesional transcriptional regulation of metabotropic glutamate receptors: implications for plasticity and excitotoxicity
- Reversal of glutamate excitotoxicity by activation of PKC‐associated metabotropic glutamate receptors in cerebellar granule cells relies on NR2C subunit expression
- excitotoxicity-induced expression of amyloid precursor protein (beta-APP) in the hippocampus and cortex of rat brain. an electron-microscopy and biochemical study.
- The metabotropic glutamate receptor agonist 1S, 3R-ACPD stimulates and modulates NMDA receptor mediated excitotoxicity in organotypic hippocampal slice …
- excitotoxicity of lathyrus sativus neurotoxin in leech retzius neurons
- Preliminary evaluation of an in vitro test for assessment of excitotoxicity by measurement of early gene (c-fos mRNA) levels
- Inhibition of excitotoxicity in cultured rat cortical neurons by a mixture of conjugated linoleic acid isomers
- Effects of kainate-mediated excitotoxicity on the expression of rat counterparts of A170 and MSP23 stress proteins in the brain
- The calretinin‐containing mossy cells survive excitotoxic insult in the gerbil dentate gyrus. Comparison of excitotoxicity‐induced neuropathological changes in the …
- Adenylyl cyclase isoforms as novel therapeutic targets: an exciting example of excitotoxicity neuroprotection
- Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity
- Human, bovine, and rabbit retinal glutamate-induced [3H] D-aspartate release: role in excitotoxicity
- Melatonin Reducesthe Expression of excitotoxicity-Triggered Markers of Apoptosis1
- Altered vulnerability to kainate excitotoxicity of transgenic-Cu/Zn SOD1 neurones
- Excitatory and inhibitory pathways modulate kainate excitotoxicity in hippocampal slice cultures
- The correlation between excitatory amino acid-induced current responses and excitotoxicity in striatal cultures
- Electroclinical and pathological studies after parenteral administration of domoic acid in freely moving nonanesthetized rats: an animal model of excitotoxicity
- Effects of a traditional Chinese medicine, Qing Nao Yi Zhi Fang, on glutamate excitotoxicity in rat fetal cerebral neuronal cells in primary culture
- excitotoxins, glutamate receptors, and excitotoxicity
- excitotoxicity can be mediated through an interaction within the optic nerve; activation of cell body NMDA receptors is not required
- Effects of ciliary neurotrophic factor on excitotoxicity and calcium-ionophore A23187-induced cell death in cultured embryonic striatal neurons
- excitotoxicity and stroke
- Neurotrophins and excitotoxicity
- Effect of the noncompetitive NMDA antagonists MK-801 and ketamine on the spastic Han-Wistar mutant: a rat model of excitotoxicity
- Gangliosides in the protection against glutamate excitotoxicity
- … proteomic analysis and characterization of the intracellular mechanisms of bis (7)-tacrine in protecting against glutamate-induced excitotoxicity in primary cultured …
- Distinct subsets of nucleus basalis neurons exhibit similar sensitivity to excitotoxicity
- Characterization of cyclothiazide-enhanced kainate excitotoxicity in rat hippocampal cultures
- The difference between mechanisms of kainate and glutamate excitotoxicity in vitro: osmotic lesion versus mitochondrial depolarization
- … between acute exposures to ethanol and acetaldehyde on neurotoxicity, nitric oxide production and NMDA-induced excitotoxicity in primary cultures of cortical …
- Spin trapping agent phenyl-N-tert-butylnitrone prevents diisopropylphosphorofluoridate-induced excitotoxicity in skeletal muscle of the rat
- Glutamate-mediated excitotoxicity
- Wernicke’s encephalopathy: an excitotoxicity hypothesis
- Tiagabine and vigabatrin reduce the severity of NMDA-induced excitotoxicity in chick retina
- Bioenergetics and excitotoxicity: the weak excitotoxic hypothesis
- Differential regulation of the expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 after excitotoxicity in a rat model of Huntington’s …
- The vulnerability of striatal projection neurons and interneurons to excitotoxicity is differentially regulated by dopamine during development
- Nitric oxide synthase inhibitors L-NAME and 7-nitroindazole protect rat hippocampus against kainate-induced excitotoxicity
- Evidence against a permissive role of the metabotropic glutamate receptor 1 in acute excitotoxicity.
- Superoxide dismutase activity in organotypic midbrain–striatum co‐cultures is associated with resistance of dopaminergic neurons to excitotoxicity
- excitotoxicity in aging and dementia
- Elevated Extracellular K+ Concentrations InhibitN-Methyl-d-Aspartate-Induced Ca2+ Influx and excitotoxicity
- Involvement of three glutamate receptor ϵ subunits in the formation of N-methyl-d-aspartate receptors mediating excitotoxicity in primary cultures of mouse cerebellar …
- Effects of glutamate-induced excitotoxicity on calretinin-expressing neuron populations in the area postrema of the rat
- excitotoxicity of glutamate and four analogs in primary spinal cord cell cultures
- Neuroprotective role of neurokinin B (NKB) on β-amyloid (25–35) induced toxicity in aging rat brain synaptosomes: involvement in oxidative stress and excitotoxicity
- Biochemical and morphological analysis of non-NMDA receptor mediated excitotoxicity in chick embryo retina
- Secobarbital Attenuates excitotoxicity but Potentiates Oxygen—Glucose Deprivation Neuronal Injury in Cortical Cell Culture
- Soluble KDI domain of γ1 laminin protects adult hippocampus from excitotoxicity of kainic acid
- Transforming growth factor-β2 increases NMDA receptor-mediated excitotoxicity in rat cerebral cortical neurons independently of glia
- Neurotrophin‐3 (NT‐3) diminishes susceptibility of the oligodendroglial lineage to AMPA glutamate receptor‐mediated excitotoxicity
- Stroke: Mechanisms of excitotoxicity and Approaches for Therapy
- Reduction of excitotoxicity-induced brain damage by the competitive NMDA antagonist CGP 40116: a longitudinal study using diffusion-weighted imaging
- GYKI 52466 protects against non-NMDA receptor-mediated excitotoxicity in primary rat hippocampal cultures
- Growth hormone releasing peptide‐6 acts as a survival factor in glutamate‐induced excitotoxicity
- Reduced NMDA receptor sensitivity may underlie the resistance of subpopulations of PVN neurons to excitotoxicity
- Differential regulation of ciliary neurotrophic factor and its receptor in the rat hippocampus in response to kainic acid-induced excitotoxicity.
- Effects of antisense oligodeoxynucleotides to NR1 on suppression of seizures and protection of cortical neurons from excitotoxicity in vivo and in vitro.
- Mitochondrial dysfunction and increased sensitivity to excitotoxicity in mice deficient in DNA mismatch repair
- excitotoxicity and Traumatic Brain Injury
- Calcium indicators and excitotoxicity in cultured cortical neurons
- excitotoxicity on cultured cortical neurons
- Enhanced excitotoxicity in primary feline neural cultures exposed to feline immunodeficiency virus (FIV)
- Mitochondria as targets for neuronal protection against excitotoxicity: a role for phenolic compounds?
- Lack of involvement of glutamate‐induced excitotoxicity in MPP+ toxicity in striatal dopaminergic terminals: possible involvement of ascorbate
- Chromatin condensation during glutamate-induced excitotoxicity of celebellar granule neurons precedes disintegration of nuclear DNA into high molecular weight …
- Oxidative stress-related proteins A170 and heme oxygenase-1 are differently induced in the rat cerebellum under kainate-mediated excitotoxicity
- excitotoxicity in amyotrophic lateral sclerosis: selective vulnerability of motor neurons
- Kainate‐induced excitotoxicity is dependent upon extracellular potassium concentrations that regulate the activity of AMPA/KA type glutamate receptors
- 17β‐estradiol does not protect cerebellar granule cells from excitotoxicity or apoptosis
- Apoptosis is induced by excitotoxicity in goldfish retina
- Tolerance of horizontal cells to excitotoxicity in the developing FVB/N mouse retina
- Prevention of kainate-induced excitotoxicity by a purine analogue.
- Ca2+-dependent kainate excitotoxicity in the chick embryonic neural retina ex vivo
- excitotoxicity induces changes in rat brain gangliosides
- Differential actions and excitotoxicity of glutamate agonists on motoneurons in adult mouse cervical spinal cord slices
- Selective glutamate antagonists block the excitotoxicity caused either by glutamate agonists or by ischemia
- Neurodegeneration induced by reversed microdialysis of NMDA; a quantitative model for excitotoxicity in vivo
- 2,7-Bis-(4-Amidinobenzylidene)-Cycloheptan-1-One Dihydrochloride, tPA Stop, Prevents tPA-Enhanced excitotoxicity Both In Vitro and In Vivo
- A derivative of a rigid glutamate analog protects the retina from excitotoxicity.
- The excitotoxicity of heterocyclic dicar☐ yclic acids in rat hippocampal slices: structure-activity relationships
- Signaling pathways to neuronal damage and apoptosis in human immunodeficiency virus type 1-associated dementia: chemokine receptors, excitotoxicity, and …
- Induction of Ornithine Decarboxylase by N‐Methyl‐D‐Aspartate Receptor Activation Is Unrelated to Potentiation of Glutamate excitotoxicity by Polyamines in …
- An unconventional hypothesis of oxidation in Alzheimer’s disease: intersections with excitotoxicity
- The study of protective effects of ginsenoside against excitotoxicity in neurons [J]
- Malonic acid and the chronic administration model of excitotoxicity
- In vivo brain microdialysis as a tool in studies of neuroprotective effects of cyclosporin A in acute excitotoxicity.
- AMPA-induced excitotoxicity increases nuclear levels of CAD, endonuclease G, and acinus and induces chromatin condensation in rat hippocampal pyramidal …
- β-Amyloid prevents excitotoxicity via recruitment of glial glutamate transporters
- Calcium homeostasis deregulation in glutamate-induced excitotoxicity and its role in neurodegenerative diseases
- Stereoselective neuroprotection by novel 2, 3-benzodiazepine non-competitive AMPA antagonists against non-NMDA receptor-mediated excitotoxicity in primary rat …
- Regulation of protein kinase C activity by taurine and β-alanine during excitotoxicity in cat and mouse cerebellar cultures
- Neonatal hypothalamic c-fos expression in an excitotoxicity-induced model of precocious puberty
- Increased sensitivity to N-methyl-D-aspartate receptor-induced excitotoxicity in cerebellar granule cells from interleukin-1 receptor type I-deficient mice
- Post-lesion administration of 5-HT1A receptor agonist 8-OH-DPAT protects cholinergic nucleus basalis neurons against NMDA excitotoxicity
- Selective enhancement of tonic inhibition by increasing ambient GABA is insufficient to suppress excitotoxicity in hippocampal neurons
- Methanol extract of Polygalae radix protects excitotoxicity in cultured neuronal cells
- Possible role for the FosB/JunD AP‐1 transcription factor complex in glutamate‐mediated excitotoxicity in cultured cerebellar granule cells
- Protection against non-NMDA receptor-mediated excitotoxicity by GYKI 52466 in mature telencephalic cultures of the rat.
- Amino acid neurotransmitter levels in the cerebral cortex of mice receiving imipenem/cilastatin-lack of excitotoxicity in the central nervous system
- Insulin growth factor-1 protects against excitotoxicity in the rat striatum
- Tachykinins and excitotoxicity in cerebellar granule cells
- Protective effect of NT-3 gene mediated by hydroxyapatite nanoparticle on the cochlea of guinea pigs injured by excitotoxicity
- Alterations of chaperone protein expression in presenilin mutant neurons in response to glutamate excitotoxicity
- Mechanisms of selective neuronal vulnerability: bioenergetics and excitotoxicity
- Glutathione prevents 2, 4, 5-trihydroxyphenylalanine excitotoxicity by maintaining it in a reduced, non-active form
- Glutamate-Induced white matter injury: excitotoxicity without synapses
- Kainic acid induced excitotoxicity and cfos expression in fibroblasts transfected with glutamate receptor subunit, GluR1
- Ibudilast prevents oligodendroglial excitotoxicity
- … neurotrophic factor-14 requires protein kinase C and mitogen-associated protein kinase kinase activation to protect the developing mouse brain against excitotoxicity
- Correlation of CGS 19755 neuroprotection against in vitro excitotoxicity and focal cerebral ischemia
- Pathological study of retinal excitotoxicity following subretinal injection of NMDA
- excitotoxicity: theories and diseases
- Contribution of astrocyte glutamate release to excitotoxicity
- Mice heterozygous for neurotrophin-3 display enhanced vulnerability to excitotoxicity in the striatum through increased expression of N-methyl-D-aspartate receptors
- Mitochondrial dysfunction in oxidative stress, excitotoxicity, and apoptosis
- excitotoxicity as a stochastic process.
- An antisense construct reduces N‐methyl‐D‐aspartate receptor 2A expression and receptor‐mediated excitotoxicity as determined by a novel flow cytometric …
- excitotoxicity and the future of stroke imaging
- excitotoxicity
- … of p75 receptors and nerve growth factor neurotrophic effects: lack of p75 immunoreactivity in striatum following physical trauma, excitotoxicity and NGF administration
- Type‐2 astrocyte‐like cells are more resistant than oligodendrocyte‐like cells against non‐N‐methyl‐D‐aspartate glutamate receptor‐mediated excitotoxicity
- Protease-activated receptor (PAR) 1-mediated anti-apoptotic effect of activated protein C on glutamate excitotoxicity in hippocampal neurons
- Batten Disease: A Typical Neuronal Storage Disease or a Genetic Neurodegenerative Disorder Characterized by excitotoxicity?
- Cl−-dependent excitotoxicity is associated with 3H2O influx in chick embryonic retina
- bcl-2 gene therapy exacerbates excitotoxicity
- Nitric oxide: implication in excitotoxicity and cerebral ischemia
- excitotoxicity in Huntington’s Disease
- Counteractive Mechanism of Tongmai Injection for excitotoxicity in Rats with Cerebral Ischemia/Reperfusion [J]
- Drug treatments to reduce excitotoxicity in vivo: a potential for α 2-adrenoceptor antagonists?
- Ester derivatives of tournefolic acid B attenuate N-methyl-D-aspartate-mediated excitotoxicity in rat cortical neurons
- Psychosine blocks quisqualate-induced glutamate excitotoxicity in hippocampal CA sector neurons
- Induction of heme oxygenase-1 in the rat brain by kainic acid-mediated excitotoxicity: the dissociation of mRNA and protein expression in hippocampus
- Intracellular signalling in glutamate excitotoxicity
- The AMPA-receptor antagonist YM90K reduces AMPA receptor-mediated excitotoxicity in rat hippocampal cultures
- Do the glutamate excitotoxicity theory and potential free radicals implication in schizophrenia aetiopathogenesis provide a new enlightenment to links between …
- excitotoxicity and neurodegenerative disorders
- excitotoxicity: Too Much Glutamate May Be Hazardous to Your Health
- excitotoxicity and Oxidative Stress in Pathogenesis of Amyotrophic Lateral Sclerosis/Motor Neuron Disease
- Effect of GDNF against kainic acid excitotoxicity on cultured neonatal rats doral root ganlian neurons
- Effects of dopamine and excitotoxicity in experimental models of Huntington’s disease
- Glutamate excitotoxicity in the immunopathogenesis of multiple sclerosis
- The role of free radicals in NMDA and glutamate excitotoxicity
- excitotoxicity, cerebral ischemia, and neuroprotection by competitive NMDA receptor antagonists
- In vitro neuronal death: contrasts between excitotoxicity and chemical hypoxia
- Cyclosporin A and Bcl-2 do not inhibit quinolinic acid-induced striatal excitotoxicity in rodents
- Effects of glutamate excitotoxicity and taurine intervention on retinal expression of glial fibrillary acid protein in rats [J]
- Developmental expression of NMDA receptors in primary cortical cell culture: relationship to function and excitotoxicity
- Epilepsy and Seizures: excitotoxicity or Excitotrophicity?
- … produce a loss of neuroprotective efficacy of competitive but not non-competitive antagonists in a model of NMDA-mediated excitotoxicity in organotypic hippocampal …
- 2-Deoxy-D-glucose protects retinal ganglion cells against excitotoxicity
- Neuroinflammation and excitotoxicity in neurobiology of HIV-1 infection and AIDS: targets for neuroprotection
- Nitric oxide, mitochondrial function and excitotoxicity
- excitotoxicity and cholinergic chemical markers during programmed motor neurone death
- Administration Model of excitotoxicity
- Amyotrophic lateral sclerosis: is excitotoxicity the key?
- ACUTE excitotoxicity IN THE ECIPPOCAMPAL
- Multiple mechanisms of excitotoxicity
- Effect of melatonin against glutamate-induced excitotoxicity on cultured cerebral cortical neurons
- Brain excitatory amino acid concentrations are lower in the neonatal pig: A buffer against excitotoxicity?
- THE PROTECTIVE EFFECTS OF TAURINE AGAINST GLUTAMATE-INDUCED excitotoxicity IN RAT RETINA [J]
- excitotoxicity in motor neurone diseases
- Role of Nitric Oxide in excitotoxicity and Memory Impairment Induced by Kanic Acid
- Mitochondrial inhibition induces glutamate excitotoxicity mediated motoneuron death
- Role of nitric oxide in excitotoxicity and memory impairment induced by kainic acid
- N-Acetylaspartate monomethyl ester increases N-acetylaspartate concentration in cultured rat hippocampal slices: Effects on excitotoxicity and levels of amino acids …
- NITRIC OXIDE, LIPIDPEROXIDATION AND TOTAL ANTIOXIDANT STATUS IN DIFFERENT REGIONS OF RAT BRAIN IN KAINIC ACID MEDIATED excitotoxicity.
- Ultrastructural studies of endothelium in NMDA-induced excitotoxicity
- excitotoxicity, genetics and neurodegeneration in amyotrophic lateral sclerosis
- The NR1-4 C-terminus interferes with N-methyl-d-aspartate receptor-mediated excitotoxicity: Evidence against a typical T/SXV-PDZ interaction
- Neuroprotective activity of neuroserpin against NMDA receptor-mediated excitotoxicity
- Can secondary brain insults exacerbate diffuse brain injuries through glutamate excitotoxicity and cyclic nucleotides system: a randomly controlled study in SD rats
- excitotoxicity and excitatory amino acid antagonists in chronic neurodegenerative diseases
- Endocytosis and autophagy in cerebral ischemia and excitotoxicity
- Blocking the pathway to excitotoxicity
- N-Methyl-D-Aspartate excitotoxicity: Is It Important in Ischemic Neuronal Injury?
- Markers of excitotoxicity in Patients: Tool for Diagnosis or Therapy?
- Effect of dizocilpine and taurine on the cerebral excitotoxicity of manganese chloride in rats
- Metabolic alterations as major contributing factors to the excitotoxicity-induced cellular damage and/or death
- excitotoxicity in Cerebral Ischemia
- Modifications of Phosphorylated Tau Immunoreactivity Linked to excitotoxicity in Neuronal Cultures
- excitotoxicity IN HUNTINGTON’S
- Seizure-linked hippocampal plasticity and protection against excitotoxicity: possible role of neuropeptide-y
- excitotoxicity, reflex responses, and evoked changes in extracellular potassium in the frog spinal cord.
- MONITORING OF excitotoxicity IN NEUROLOGIC DISORDERS
- Role of excitotoxicity in the degeneration of motor neurones in ALS
- Neuron protection of N-acetylcysteine on hippocampal neuron against glutamate excitotoxicity
- Nerve growth factor protects cholinergic neurons against quinolinic acid-induced excitotoxicity in wistar rats
- AND ASSESSMENT OF excitotoxicity MODILATION BY NEUROSTEROIDS
- excitotoxicity in ALS: Investigations of underlying molecular mechanisms and evaluation of neuroprotective strategies
- Does Ketamine Affect excitotoxicity?
- Characteristics of direct and indirect excitotoxicity in the mammalian hippocampus in vitro.
- AMPA‐induced excitotoxicity stimulates calpain activity and is exacerbated by tumor necrosis factor‐α;(TNF‐α) in the CA1 and CA3 regions of the hippocampus in an …
- Noradrenergic Modulation of excitotoxicity
- Glutamate excitotoxicity in Multiple Sclerosis
- Microglia recruitment during excitotoxicity
- The process and purpose of establishing excitotoxicity model with hippocampal neurons
- Chromatin condensation during glutamate-induced excitotoxicity of cerebellar [correction of celebellar] granule neurons precedes disintegration of nuclear DNA into …
- Development of excitotoxicity model with primary hippocampal neurons and implications of viability essay
- AMPA receptor mediated excitotoxicity in ALS: pathophysiology and neuropharmacology
- Excito-depletion: An Upside Down View of excitotoxicity Following Brain Injury
- KN-62 provides neuroprotection against glutamate-induced excitotoxicity in neurons.
- Neuroprotectins A and B, Two New Bicyclohexapeptides Protecting Primary Cultured Neurons from excitotoxicity
- excitotoxicity plays an important role in the pathologic progress of amyotrophic lateral sclerosis.
- Neuroprotective effects of nGBE against glutamate excitotoxicity
- excitotoxicity, Glutamate, Calcium and Neuronal Damage
- Neuroprotective properties of memantine in different models of excitotoxicity
- Fourier transform infrared spectroscopic investigation of excitotoxicity-protective mechanism of monoclonal antibody against NMDAR
- Tardive dyskinesia: An excitotoxicity hypothesis investigated in a rat model.
- Glutamate excitotoxicity in pathogenesis of multiple sclerosis
- Inhibiting glutamate excitotoxicity in spinal cord injury
- Counteractive Mechanism of Tongmai Injection for excitotoxicity in Rats with Cerebral Ischemia/Reperfusion
- Mechanisms of kainate-induced neuronal excitotoxicity.
- Glutamate excitotoxicity In Epilepsy And Ischemia
- The role of the NMDA receptor in the developmental onset of excitotoxicity in rat cortical neurons in vitro.
- An in Vivo Study of excitotoxicity in Generalized Epilepsy with MRS at 0.5 Tesla
- Na and K Changes Due to excitotoxicity are Mediated by Glutamate Transporters
- Characterization of the Molecular Mechanisms by which Endocytosed AMP AR Mediates NMDAR-Mediated Synaptic Plasticity and excitotoxicity
- Modulation of kainate-induced excitotoxicity in rats
- Secondary Neuronal Injury After Head Trauma: Role of excitotoxicity
- Involvement of Antioxidant Enzymes in NMDA-Induced Retinal excitotoxicity
- Hyperexcitability in adrenal cells after culture in ethanol: withdrawal or excitotoxicity.
- Myristicae Semen Extract Protects excitotoxicity in Cultured Neuronal Cells
- Glutamate excitotoxicity on primary cultured hippocampal neurons
- INVOLVEMENT OF GLUTAMINE SYNTHETASE IN KAINIC ACID MEDIATED excitotoxicity IN RAT BRAIN.
- Digital imaging of free intracellular calcium: a quantitative approach to assess excitotoxicity and neuronal protection in vitro
- The effect of glutamate excitotoxicity on the dopaminergic cells in the rat retina
- Involvement of excitotoxicity or oxidative stress in the pathophysiology of white and grey matter injury
- Molecular mechanisms of Tay Sachs Disease: calcium, excitotoxicity, and apoptosis
- Neuroprotective effects of stearic acid in primarily cultured hippocampal neurons insulted by excitotoxicity
- Glutamate excitotoxicity: An apoptosis-necrosis continuum of neuronal cell death.
- The effects of excitotoxicity and microglial activation on oligodendrocyte survival
- Regulation of effector pathways involved in protection from NMDA receptor-induced excitotoxicity in a mouse model of Huntington’s disease
- Neuronal apoptosis in excitotoxicity: involvement of nitric oxide and cytoskeletal damage
- Interactions between excitotoxicity and lysosomal inhibition: Implications for Alzheimer’s disease pathogenesis
- Interactions of excitatory neurotransmitters and xenobiotics in excitotoxicity and oxidative stress
- The Effects of Ginkgo Biloba Extract on Glutamate excitotoxicity in vitro and Its Correlation with Cholesterol Pathway
- Effect of Minocycline on the Survival of Cultered Retinal Neurons in Glutamate excitotoxicity Assays
- Acute DNA fragmentation detected by Comet Assay in excitotoxicity
- LIGA20 ganglioside prevents excitotoxicity through activation of TrkB receptor
- Kainate Receptors in the Striatum: Implications for excitotoxicity in Huntington’s Disease
- Purines, Lactate and Myo-Inositol in CSF Might Reflect excitotoxicity in Inherited Metabolic Disorders
- Volume-sensitive chloride channel involved in necrotic neuronal death by excitotoxicity
- ROLE OF CITRULLINE-NITRIC OXIDE CYCLE ENZYMES AND ARGINASE IN KAINIC ACID MEDIATED excitotoxicity.
- An orchestra of glutamate receptors and transporters in synaptic transmission, plasticity and excitotoxicity
- Neuroprotective Effects of Lithium on NMDA-induced excitotoxicity in Mouse Cerebrum
- Correction: Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity
- Dantrolene protects motoneurons in culture against AMPA receptor mediated excitotoxicity
- Protein Kinase B (PKB) and Protein Kinase C (PKC) in N-Methyl-D-Aspartate (NMDA)-Induced excitotoxicity in Rats
- Glutamate-induced changes in intracellular calcium and magnesium in rat forebrain neurons in vitro: Relationship to excitotoxicity.
- The protective effect of CDP-choline on neuronal changes in a model of slow glutamate excitotoxicity in vitro
- 2-deoxy-D-glucose Protects Retinal Ganglion Cells against N-methyl-D-aspartate Mediated excitotoxicity
- ACh Receptor Activation Links Two Separate Signaling Proteins to Neuroprotection Against Glutamate–Induced excitotoxicity in Isolated Pig Retinal Ganglion Cells
- EFFECT OF CALCIUM CHANNEL ANTAGONISTS ON EAA-MEDIATED excitotoxicity IN ETHANOL WITHDRAWN NEOCORTICAL CULTURES
- Effects of glutamate excitotoxicity and taurine intervention on retinal expression of glial fibrillary acid protein in rats
- Neuroprotective effects of calpain inhibitor MDL 28170 in a model of intravitreal excitotoxicity
- Histological changes in brain tissue of rat induced neuronal excitotoxicity by NMDA (N-methyl-D-asparate)
- excitotoxicity of AMPA and kainate receptor activation and desensitization in cultured neurons
- AIDS DEMENTIA AS A FORM OF excitotoxicity: POTENTIAL THERAPY WITH NMDA OPEN-CHANNEL BLOCKERS AND REDOX CONGENERS OF NITRIC …
- Mutant huntingtin enhanced sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity
- A possible mechanism of excitotoxicity: Autoregulation of glutamate release from hippocampal mossy fiber terminals.
- Actions and Interactions of Cholinergic and Excitatory Aminoacid Receptors on Phosphoinositide Signals, excitotoxicity and Neuroplasticity
- AIDS dementia as a form of excitotoxicity: potential therapy with NMDA open-channel blockers and redox congeners of nitric oxide
- Hypothetical Mechanisms of G protein-coupled neurodegeneration in glutamate excitotoxicity in human SH-SY5Y neuroblastoma cells
- The role of mitochondria in N-methyl-D-aspartate receptor-mediated excitotoxicity: A mechanistic explanation for neurodegeneration.
- Mechanisms of domoic acid action: Glutamate receptor-mediated excitotoxicity and changes of hippocampal neurotransmission and synaptic plasticity
- Crude Extract of Zizyphi Jujube Semen Protects Kainic Acid-induced excitotoxicity in Cultured Rat Neuronal Cells
- Protective Effects of Na+/H+ Exchanger Inhibition Against Glutamate excitotoxicity Occur through Blockade of Mitochondrial Ca2+ Overload
- Protective Effects of Shenqi-wan and Its Fractions on N-methyl-D-aspartate-induced excitotoxicity in Rat Hippocampal CA1 Region
- Hypothetical Mechanisms of G protein-coupled neurodegeneration in glutamate excitotoxicity in human SH-SY5Y neuroblastoma cells
- Dibenzylbutyrolactone lignans from Torreya nucifera Protect CuItured Rat Cortical Neurons from Glutamate-lnduced excitotoxicity
- Proteomics Analysis of the Retina of EAAC1–Knock Out Mice: Neuroprotective Effect of PDGF Against Glutamate–Induced excitotoxicity in Retinal Ganglion Cells
- Delayed preconditioning with rosuvastatin protects cultured rat cortical neurons against oxygen‐glucose deprivation and excitotoxicity
- P25 IN VITRO NEUROPROTECTIVE EFFECTS OF MTEP, A SELECTIVE MGLUR5 ANTAGONIST AGAINST KAINATE–INDUCED excitotoxicity.
- Olfactory receptor neurons persist during extensive remodeling of the olfactory bulb following NMDA-induced excitotoxicity
- THE AUTOCRINE excitotoxicity OF ANTILLATOXIN, A NOVEL LIPOPEPTIDE DERIVED FROM THE PANTROPICAL MARINE CYANOBACTERIUM …
- Neuroprotective effect of betaine against N-methyl-D-aspartate excitotoxicity in hippocampal slice culture
- Intrinsic optical signals characterizing acute excitotoxicity in the hippocampal slice evoked by the marine toxin domoic acid.
- In vitro studies with AMPA and NMDA receptor antagonists and modulators on synaptic transmission, LTP and excitotoxicity-implications for therapeutic safety
- The autocrine excitotoxicity of antillatoxin, a novel lipopeptide derived from the antropical [sic] marine cyanobacterium Lyngbya majuscula
- Low Mg2+-induced Calcium Spiking Protects Against Subsequent Longer Exposure-induced excitotoxicity in Cultured Rat Hippocampal Neurons
- Nitric oxid inhibits excitotoxicity of glutamate in purified chick embryo retinal cultures: role of NMDA receptors; Oxido nitrico inibe a excitotoxicidade do glutamato em …
- … Huntingtin-mediated alterations of N-Methyl-D-Aspartate receptor currents and downstream events underlying enhanced excitotoxicity in Huntington’s disease
- A Possible Central Mechanism in Autism Spectrum Disorders: Interaction of Activated Microglia, excitotoxicity, Reactive Oxygen and Nitrogen Species, Lipid …
- Neuroprotective effect of Acanthopanax sessiliflorm Stems and Roots against N-methyl-D-aspartate excitotoxicity in rat organotypic hippocampal slice culture
- 1069. The HSV-2 Vector ΔRR Prevents excitotoxicity-Induced Neuronal Cell Loss through Activation of Survival Pathways and Glial Cell Modulation
- Protective Effects of Li’s No. 5 on Glutamate excitotoxicity on Primary Cultured Cortical Neurons by Serum Pharmacological Test [J]
- Molecular pathogenesis of Huntington’s disease: the role of excitotoxicity
- Change of the Ca~(2+) density in the cortical neurons after excitotoxicity
- 14 Minocycline in Cerebral Ischemia and excitotoxicity
- STUDIES ON THE CHANGES OF Ca-(2+)/CaM PKⅡ ACTIVITY ANDTHEIR RELATION WITH excitotoxicity OF BRAIN ISCHEMIA
- Insulin-like growth factor type 1 receptor activity promotes survival and inhibits glutamate-induced excitotoxicity of cortical neurons
- The Role of Glia in excitotoxicity and Stroke
- Non-NMDA Glutamate Receptors in the Regulation of Neuronal Ca2+ and excitotoxicity
- IL-6 Decreases Low Mg2+-induced excitotoxicity in Cultured Rat Hippocampal Neurons by Inhibition of [Ca2+] i Spikes and Activation of RAS/MAPK and JAK-STAT
- IL-6 Decreases Low [Mg2+] o-induced excitotoxicity in Cultured Rat Hippocampal Neurons
- Metabotropic and ionotropic transducers of glutamate signal inversely control cytoplasmic Ca 2+ concentration and excitotoxicity
- The HSV-2 protein ICP10PK protects CNS neurons from NMDA-induced excitotoxicity in vitro and in vivo
- Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases
- Calcium, ischemia and excitotoxicity
- excitotoxicity: bridge to various triggers in neurodegenerative disorders
- excitotoxicity and stroke: identifying novel targets for neuroprotection
- A further update on the role of excitotoxicity in the pathogenesis of Parkinson’s disease
- Methylxanthines, seizures, and excitotoxicity
- Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity
- excitotoxicity in ALS: overstimulation, or overreaction?
- excitotoxicity in the pathogenesis of autism
- Slow excitotoxicity in Alzheimer’s disease
- excitotoxicity in the pathogenesis of neurological and psychiatric disorders: Therapeutic implications
- Spare respiratory capacity, oxidative stress and excitotoxicity
- Neurodegeneration in multiple sclerosis: the role of oxidative stress and excitotoxicity
- Kainate receptors in epilepsy and excitotoxicity
- Interleukin‐1β: a bridge between inflammation and excitotoxicity?
- Mechanisms underlying the loss of mitochondrial membrane potential in glutamate excitotoxicity
- Oxidative stress and excitotoxicity: a therapeutic issue in multiple sclerosis?
- Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients
- Glutamate-mediated excitotoxicity in schizophrenia: a review
- Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation
- A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics
- Multiple sclerosis and glutamate excitotoxicity
- Misplaced NMDA receptors in epileptogenesis contribute to excitotoxicity
- Chemical pathology of homocysteine. IV. excitotoxicity, oxidative stress, endothelial dysfunction, and inflammation
- Neuroprotective function for ramified microglia in hippocampal excitotoxicity
- Beyond the critical point: An overview of excitotoxicity, calcium overload and the downstream consequences
- excitotoxicity triggered by Neurobasal culture medium
- Amyotrophic lateral sclerosis and excitotoxicity: from pathological mechanism to therapeutic target
- Molecular mechanisms of necrosis in glioblastoma: the role of glutamate excitotoxicity
- Multiple interacting cell death mechanisms in the mediation of excitotoxicity and ischemic brain damage: a challenge for neuroprotection
- White matter vulnerability to ischemic injury increases with age because of enhanced excitotoxicity
- Amyloid β, glutamate, excitotoxicity in Alzheimer’s disease: are we on the right track?
- Mechanisms of neuronal protection against excitotoxicity, endoplasmic reticulum stress, and mitochondrial dysfunction in stroke and neurodegenerative …
- Mechanisms of synaptic dysfunction and excitotoxicity in Huntington’s disease
- Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicity
- Cortical cultures coupled to micro-electrode arrays: a novel approach to perform in vitro excitotoxicity testing
- ATP signaling in brain: release, excitotoxicity and potential therapeutic targets
- Quinolinic acid, an endogenous molecule combining excitotoxicity, oxidative stress and other toxic mechanisms
- Cholesterol loss during glutamate‐mediated excitotoxicity
- Is there a role for glutamate-mediated excitotoxicity in inflammation-induced depression?
- Update of cell damage mechanisms in thiamine deficiency: focus on oxidative stress, excitotoxicity and inflammation
- Abnormalities in glutamate metabolism and excitotoxicity in the retinal diseases
- Inhibition of reactive gliosis attenuates excitotoxicity-mediated death of retinal ganglion cells
- Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity
- Dopamine protects neurons against glutamate-induced excitotoxicity
- FTY720 attenuates excitotoxicity and neuroinflammation
- Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death
- Spreading depolarizations mediate excitotoxicity in the development of acute cortical lesions
- Polysaccharides from wolfberry antagonizes glutamate excitotoxicity in rat cortical neurons
- MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons
- Microglial CB2 cannabinoid receptors are neuroprotective in Huntington’s disease excitotoxicity
- Mitochondrial disturbances, excitotoxicity, neuroinflammation and kynurenines: novel therapeutic strategies for neurodegenerative disorders
- Postsynaptic mechanisms of excitotoxicity: Involvement of postsynaptic density proteins, radicals, and oxidant molecules
- Serine racemase deletion protects against cerebral ischemia and excitotoxicity
- Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP
- Hyperactive somatostatin interneurons contribute to excitotoxicity in neurodegenerative disorders
- Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly (ADP-ribose) polymer-induced cell death
- P2X7 receptor blockade prevents ATP excitotoxicity in neurons and reduces brain damage after ischemia
- Neuroprotective effects of naturally occurring polyphenols on quinolinic acid‐induced excitotoxicity in human neurons
- Protection of apigenin against kainate-induced excitotoxicity by anti-oxidative effects
- α2 adrenergic modulation of NMDA receptor function as a major mechanism of RGC protection in experimental glaucoma and retinal excitotoxicity
- Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons
- An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis
- Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals
- excitotoxicity and oxidative stress in acute ischemic stroke
- Cellular prion protein and NMDA receptor modulation: protecting against excitotoxicity
- NMDA receptor-mediated excitotoxicity depends on the coactivation of synaptic and extrasynaptic receptors
- VEGF protects motor neurons against excitotoxicity by upregulation of GluR2
- In vivo evidence for NMDA receptor-mediated excitotoxicity in a murine genetic model of Huntington disease
- Adiponectin protects rat hippocampal neurons against excitotoxicity
- L-Lactate protects neurons against excitotoxicity: implication of an ATP-mediated signaling cascade
- Necroptosis contributes to the NMDA-induced excitotoxicity in rat’s cultured cortical neurons
- Taming glutamate excitotoxicity: strategic pathway modulation for neuroprotection
- Down-regulation of Homer1b/c attenuates glutamate-mediated excitotoxicity through endoplasmic reticulum and mitochondria pathways in rat cortical neurons
- An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation
- NR1 and GluR2 expression mediates excitotoxicity in chronic hypobaric hypoxia
- Calpains and delayed calcium deregulation in excitotoxicity
- Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration
- Altered cholesterol homeostasis contributes to enhanced excitotoxicity in Huntington’s disease
- Glutamate excitotoxicity and oxidative stress in epilepsy: modulatory role of melatonin
- Mechanisms underlying the neurotoxicity induced by glyphosate-based herbicide in immature rat hippocampus: involvement of glutamate excitotoxicity
- Histone deacetylase inhibitors preserve white matter structure and function during ischemia by conserving ATP and reducing excitotoxicity
- Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity‐induced axonal degeneration
- … : motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity
- Coenzyme Q10 inhibits glutamate excitotoxicity and oxidative stress–mediated mitochondrial alteration in a mouse model of glaucoma
- excitotoxicity as a common mechanism for fetal neuronal injury with hypoxia and intrauterine inflammation
- Cdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicity
- Normobaric hyperoxia is associated with increased cerebral excitotoxicity after severe traumatic brain injury
- Mitochondria, bioenergetics and excitotoxicity: new therapeutic targets in perinatal brain injury
- The metabolic response to excitotoxicity–lessons from single-cell imaging
- excitotoxicity and metabolic crisis are associated with spreading depolarizations in severe traumatic brain injury patients
- GABAergic excitotoxicity injury of the immature hippocampal pyramidal neurons’ exposure to isoflurane
- excitotoxicity in acute encephalopathy with biphasic seizures and late reduced diffusion
- In vivo and in vitro effects of multiple sclerosis immunomodulatory therapeutics on glutamatergic excitotoxicity
- Neuroprotective effect of magnesium acetyltaurate against NMDA-induced excitotoxicity in rat retina
- Glutamate excitotoxicity inflicts paranodal myelin splitting and retraction
- Perspectives on neuroinflammation and excitotoxicity: a neurotoxic conspiracy?
- Endoplasmic reticulum Ca2+ release through ryanodine and IP3 receptors contributes to neuronal excitotoxicity
- excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage
- Axonal degeneration induced by glutamate excitotoxicity is mediated by necroptosis
- excitotoxicity and oxidative stress in acute stroke
- Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity
- Neuroprotective effects of yokukansan, a traditional Japanese medicine, on glutamate-mediated excitotoxicity in cultured cells
- Mitogen‐activated protein kinase‐signaling regulates the ability of Müller glia to proliferate and protect retinal neurons against excitotoxicity
- Role of nonsynaptic GluN2B-containing NMDA receptors in excitotoxicity: evidence that fluoxetine selectively inhibits these receptors and may have neuroprotective …
- Nicotinamide Prevents NAD+ Depletion and Protects Neurons Against excitotoxicity and Cerebral Ischemia: NAD+ Consumption by SIRT1 may Endanger …
- Microglial contact prevents excess depolarization and rescues neurons from excitotoxicity
- Simvastatin is the statin that most efficiently protects against kainate-induced excitotoxicity and memory impairment
- Tinospora cordifolia as a potential neuroregenerative candidate against glutamate induced excitotoxicity: an in vitro perspective
- Differentiation renders susceptibility to excitotoxicity in HT22 neurons
- Excess cerebral TNF causing glutamate excitotoxicity rationalizes treatment of neurodegenerative diseases and neurogenic pain by anti-TNF agents
- Glutamate excitotoxicity and Ca2+-regulation of respiration: Role of the Ca2+ activated mitochondrial transporters (CaMCs)
- Involvement of the GluN2A and GluN2B subunits in synaptic and extrasynaptic N-methyl-D-aspartate receptor function and neuronal excitotoxicity
- P38 MAPK is involved in enhanced NMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease
- Progesterone inhibition of voltage-gated calcium channels is a potential neuroprotective mechanism against excitotoxicity
- Vascular endothelial growth factor protects spinal cord motoneurons against glutamate‐induced excitotoxicity via phosphatidylinositol 3‐kinase
- Adiponectin protects hippocampal neurons against kainic acid-induced excitotoxicity
- PGC-1α negatively regulates extrasynaptic NMDAR activity and excitotoxicity
- NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons
- Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFα pathway and protection by …
- NR2D-containing NMDA receptors mediate tissue plasminogen activator-promoted neuronal excitotoxicity
- Mechanisms of tau and Aβ-induced excitotoxicity
- Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB
- The Tau/A152T mutation, a risk factor for frontotemporal‐spectrum disorders, leads to NR 2B receptor‐mediated excitotoxicity
- Progesterone with vitamin D affords better neuroprotection against excitotoxicity in cultured cortical neurons than progesterone alone
- Caloric restriction increases brain mitochondrial calcium retention capacity and protects against excitotoxicity
- Abnormal visual gain control and excitotoxicity in early-onset Parkinson’s disease Drosophila models
- Data of multiple regressions analysis between selected biomarkers related to glutamate excitotoxicity and oxidative stress in Saudi autistic patients
- Changes in brain cholesterol metabolome after excitotoxicity
- Carnosine protects against permanent cerebral ischemia in histidine decarboxylase knockout mice by reducing glutamate excitotoxicity
- Mesenchymal stem cells protect CNS neurons against glutamate excitotoxicity by inhibiting glutamate receptor expression and function
- Cytoprotective effects of melatonin on C6 astroglial cells exposed to glutamate excitotoxicity and oxidative stress
- Neuronal Gap Junctions Are Required for NMDA Receptor–Mediated excitotoxicity: Implications in Ischemic Stroke
- … exposure to glyphosate-based herbicide and depressive-like behavior in adult offspring: Implication of glutamate excitotoxicity and oxidative stress
- Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity
- β-N-methylamino-L-alanine toxicity in PC12: excitotoxicity vs. misincorporation
- Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington’s disease: a STEP in the resistance to excitotoxicity
- excitotoxicity and focal cerebral ischemia induce truncation of the NR2A and NR2B subunits of the NMDA receptor and cleavage of the scaffolding protein …
- Adipose-derived mesenchymal stem cells protect PC12 cells from glutamate excitotoxicity-induced apoptosis by upregulation of XIAP through PI3-K/Akt activation
- Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity
- TNF‐α‐mediates neuroprotection against glutamate‐induced excitotoxicity via NF‐κB‐dependent up‐regulation of KCa2.2 channels
- The beta-lactam antibiotic, ceftriaxone, provides neuroprotective potential via anti-excitotoxicity and anti-inflammation response in a rat model of traumatic brain injury
- Involvement of PrP C in kainate-induced excitotoxicity in several mouse strains
- Zinc binding to S100B affords regulation of trace metal homeostasis and excitotoxicity in the brain
- Ammonia mediates methamphetamine-induced increases in glutamate and excitotoxicity
- Increased mitochondrial fission and volume density by blocking glutamate excitotoxicity protect glaucomatous optic nerve head astrocytes
- Subventricular zone neural progenitors protect striatal neurons from glutamatergic excitotoxicity
- Preventing NAD+ depletion protects neurons against excitotoxicity: bioenergetic effects of mild mitochondrial uncoupling and caloric restriction
- L-lactate-mediated neuroprotection against glutamate-induced excitotoxicity requires ARALAR/AGC1
- excitotoxicity of TNFα derived from KA activated microglia on hippocampal neurons in vitro and in vivo
- Biodegradable spheres protect traumatically injured spinal cord by alleviating the glutamate‐induced excitotoxicity
- Chemical analysis and effect of blueberry and lingonberry fruits and leaves against glutamate-mediated excitotoxicity
- Brimonidine blocks glutamate excitotoxicity-induced oxidative stress and preserves mitochondrial transcription factor a in ischemic retinal injury
- Chronic NMDA administration increases neuroinflammatory markers in rat frontal cortex: cross-talk between excitotoxicity and neuroinflammation
- Probucol modulates oxidative stress and excitotoxicity in Huntington’s disease models in vitro
- Single-cell imaging of bioenergetic responses to neuronal excitotoxicity and oxygen and glucose deprivation
- Protection from glutamate-induced excitotoxicity by memantine
- excitotoxicity: an organized crime at the cellular level
- Glutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagy
- Extrasynaptic NMDA receptor in excitotoxicity: function revisited
- Neuroprotective effect of resveratrol against glutamate-induced excitotoxicity
- Blockade of monoacylglycerol lipase inhibits oligodendrocyte excitotoxicity and prevents demyelination in vivo
- System xc− regulates microglia and macrophage glutamate excitotoxicity in vivo
- Recent findings on neuroprotection against excitotoxicity in the hippocampus of female rats
- Prolactin reduces the damaging effects of excitotoxicity in the dorsal hippocampus of the female rat independently of ovarian hormones
- Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation
- The interplay of microRNAs and post-ischemic glutamate excitotoxicity: an emergent research field in stroke medicine
- Synaptic activity protects neurons against calcium-mediated oxidation and contraction of mitochondria during excitotoxicity
- Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice
- excitotoxicity and metabolic changes in association with infarct progression
- Prolactin mediates neuroprotection against excitotoxicity in primary cell cultures of hippocampal neurons via its receptor
- excitotoxicity downregulates TrkB. FL signaling and upregulates the neuroprotective truncated TrkB receptors in cultured hippocampal and striatal neurons
- Glutamate excitotoxicity linked to spermine oxidase overexpression
- Glutamatergic metabolites, volume and cortical thickness in antipsychotic-naive patients with first-episode psychosis: implications for excitotoxicity
- The neuroprotective effects of SIRT1 on NMDA-induced excitotoxicity
- Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus
- Neuroprotection by donepezil against glutamate excitotoxicity involves stimulation of α7 nicotinic receptors and internalization of NMDA receptors
- Total oligomeric flavonoids of Cyperus rotundus ameliorates neurological deficits, excitotoxicity and behavioral alterations induced by cerebral ischemic–reperfusion …
- Ethanol and adult CNS neurodamage: oxidative stress, but possibly not excitotoxicity.
- … medium of human adipose-derived mesenchymal stem cells mediates protection in neurons following glutamate excitotoxicity by regulating energy …
- Calpain-dependent degradation of nucleoporins contributes to motor neuron death in a mouse model of chronic excitotoxicity
- β-Caryophyllene protects the C6 glioma cells against glutamate-induced excitotoxicity through the Nrf2 pathway
- excitotoxicity triggered by neonatal monosodium glutamate treatment and blood–brain barrier function
- Novel model for the mechanisms of glutamate-dependent excitotoxicity: role of neuronal gap junctions
- Direct interaction between GluR2 and GAPDH regulates AMPAR-mediated excitotoxicity
- Galantamine potentiates the neuroprotective effect of memantine against NMDA‐induced excitotoxicity
- Identifying the primary site of pathogenesis in amyotrophic lateral sclerosis–vulnerability of lower motor neurons to proximal excitotoxicity
- Regulated expression of surface AMPA receptors reduces excitotoxicity in auditory neurons
- Acidotoxicity via ASIC1a mediates cell death during oxygen glucose deprivation and abolishes excitotoxicity
- Susceptibility to excitotoxicity in aged hippocampal cultures and neuroprotection by non‐steroidal anti‐inflammatory drugs: role of mitochondrial calcium
- Glutamate excitotoxicity is involved in the induction of paralysis in mice after infection by a human coronavirus with a single point mutation in its spike protein
- L-theanine protects the APP (Swedish mutation) transgenic SH-SY5Y cell against glutamate-induced excitotoxicity via inhibition of the NMDA receptor pathway
- Post-ischemic administration of nimodipine following focal cerebral ischemic-reperfusion injury in rats alleviated excitotoxicity, neurobehavioural alterations and …
- Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by …
- Experimental glutamatergic excitotoxicity in rabbit retinal ganglion cells: block by memantine
- Ceftriaxone rescues hippocampal neurons from excitotoxicity and enhances memory retrieval in chronic hypobaric hypoxia
- Anthocyanins Protect against Kainic Acid‐induced excitotoxicity and Apoptosis via ROS‐activated AMPK Pathway in Hippocampal Neurons
- Phosphorylation of tau at Y18, but not tau-fyn binding, is required for tau to modulate NMDA receptor-dependent excitotoxicity in primary neuronal culture
- Myelin‐associated glycoprotein protects neurons from excitotoxicity
- Agathisflavone, a flavonoid derived from Poincianella pyramidalis (Tul.), enhances neuronal population and protects against glutamate excitotoxicity
- Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: implications for excitotoxicity
- Differential molecular targets for neuroprotective effect of chlorogenic acid and its related compounds against glutamate induced excitotoxicity and oxidative stress in …
- Unraveling the neuroprotective mechanisms of PrPC in excitotoxicity
- Molecular mechanisms of NMDA receptor-mediated excitotoxicity: implications for neuroprotective therapeutics for stroke
- Inhibition of Bcl-xL prevents pro-death actions of ΔN-Bcl-xL at the mitochondrial inner membrane during glutamate excitotoxicity
- Alterations in mGluR5 expression and signaling in Lewy body disease and in transgenic models of alpha-synucleinopathy–implications for excitotoxicity
- Alzheimer’s disease: recent concepts on the relation of mitochondrial disturbances, excitotoxicity, neuroinflammation, and kynurenines
- A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity
- Cannabinoid receptor agonists reduce the short-term mitochondrial dysfunction and oxidative stress linked to excitotoxicity in the rat brain
- NeuroEPO preserves neurons from glutamate-induced excitotoxicity
- C9orf72 dipeptide repeats cause selective neurodegeneration and cell-autonomous excitotoxicity in Drosophila glutamatergic neurons
- Pharmacological enhancement of glutamate transport reduces excitotoxicity in vitro
- Glutamate excitotoxicity induced by orally administered propionic acid, a short chain fatty acid can be ameliorated by bee pollen
- Progesterone inhibits estrogen‐mediated neuroprotection against excitotoxicity by down‐regulating estrogen receptor‐β
- Ginsenoside Rd Protects Neurons Against Glutamate-Induced excitotoxicity by Inhibiting Ca2+ Influx
- DR-region of Na+/K+ ATPase is a target to treat excitotoxicity and stroke
- Brain energy metabolism in glutamate-receptor activation and excitotoxicity: role for APC/C-Cdh1 in the balance glycolysis/pentose phosphate pathway
- Alcohol, excitotoxicity and adult brain damage: an experimentally unproven chain-of-events
- A ‘danse macabre’: tau and F yn in STEP with amyloid beta to facilitate induction of synaptic depression and excitotoxicity
- Iron is a potential key mediator of glutamate excitotoxicity in spinal cord motor neurons
- Chronic stress enhances methamphetamine‐induced extracellular glutamate and excitotoxicity in the rat striatum
- The role of canonical transient receptor potential channels in seizure and excitotoxicity
- Role of adaptor protein MyD88 in TLR-mediated preconditioning and neuroprotection after acute excitotoxicity
- Kainic acid-induced excitotoxicity experimental model: protective merits of natural products and plant extracts
- Microglia activation contributes to quinolinic acid-induced neuronal excitotoxicity through TNF-α
- Growth hormone protects against kainate excitotoxicity and induces BDNF and NT3 expression in chicken neuroretinal cells
- A novel Conus snail polypeptide causes excitotoxicity by blocking desensitization of AMPA receptors
- Lactation is a natural model of hippocampus neuroprotection against excitotoxicity
- Kainate-induced delayed onset of excitotoxicity with functional loss unrelated to the extent of neuronal damage in the in vitro spinal cord
- Calpain-mediated degradation of drebrin by excitotoxicity in vitro and in vivo
- Dock3 interaction with a glutamate-receptor NR2D subunit protects neurons from excitotoxicity
- Homocysteine-induced acute excitotoxicity in cerebellar granule cells in vitro is accompanied by PP2A-mediated dephosphorylation of tau
- Sulforaphane prevents methylmercury-induced oxidative damage and excitotoxicity through activation of the Nrf2-ARE pathway
- Neuroprotection of the leaf and stem of Vitis amurensis and their active compounds against ischemic brain damage in rats and excitotoxicity in cultured neurons
- The β2-adrenoceptor agonist clenbuterol elicits neuroprotective, anti-inflammatory and neurotrophic actions in the kainic acid model of excitotoxicity
- Oncostatin M promotes excitotoxicity by inhibiting glutamate uptake in astrocytes: implications in HIV-associated neurotoxicity
- Mild mitochondrial uncoupling’induced protection against neuronal excitotoxicity requires AMPK activity
- Kainate-mediated excitotoxicity induces neuronal death in the rat spinal cord in vitro via a PARP-1 dependent cell death pathway (Parthanatos)
- Humanin attenuates NMDA-induced excitotoxicity by inhibiting ROS-dependent JNK/p38 MAPK pathway
- Intrinsically photosensitive retinal ganglion cells are resistant to N-methyl-D-aspartic acid excitotoxicity
- Inhibition of cPLA2 activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress‐induced cell death
- Protection of cortical neurons from excitotoxicity by conjugated linoleic acid
- Novel regimen through combination of memantine and tea polyphenol for neuroprotection against brain excitotoxicity
- Patrolling monocytes play a critical role in CX3CR1-mediated neuroprotection during excitotoxicity
- Glutamatergic nervous system degeneration in a C. elegans TauA152T tauopathy model involves pathways of excitotoxicity and Ca2+ dysregulation
- Withanone, an active constituent from Withania somnifera, affords protection against NMDA-induced excitotoxicity in neuron-like cells
- Guanosine protects against traumatic brain injury-induced functional impairments and neuronal loss by modulating excitotoxicity, mitochondrial dysfunction, and …
- NMDA and AMPA receptor mediated excitotoxicity in cerebral cortex of streptozotocin induced diabetic rat: ameliorating effects of curcumin
- Attenuation of glutamate-induced excitotoxicity by Withanolide-A in neuron-like cells: role for PI3K/Akt/MAPK signaling pathway
- Hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats
- The effects of NAD+ on apoptotic neuronal death and mitochondrial biogenesis and function after glutamate excitotoxicity
- Topiramate protects against glutamate excitotoxicity via activating BDNF/TrkB-dependent ERK pathway in rodent hippocampal neurons
- excitotoxicity induced by realgar in the rat hippocampus: the involvement of learning memory injury, dysfunction of glutamate metabolism and NMDA receptors
- Tetramethylpyrazine inhibits activities of glioma cells and glutamate neuro-excitotoxicity: potential therapeutic application for treatment of gliomas
- Insight into glutamate excitotoxicity from synaptic zinc homeostasis
- Anesthetic protection of neurons injured by hypothermia and rewarming: roles of intracellular Ca2+ and excitotoxicity
- p53 mediates autophagy activation and mitochondria dysfunction in kainic acid-induced excitotoxicity in primary striatal neurons
- Synthetic and endogenous cannabinoids protect retinal neurons from AMPA excitotoxicity in vivo, via activation of CB1 receptors: involvement of PI3K/Akt and MEK …
- Protective role of arginase II in cerebral ischemia and excitotoxicity
- Neuroprotective effects of daphnetin against NMDA receptor-mediated excitotoxicity
- ATP leakage induces P2XR activation and contributes to acute synaptic excitotoxicity induced by soluble oligomers of β-amyloid peptide in hippocampal neurons
- A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicity
- Rapid loss of glutamine synthetase from astrocytes in response to hypoxia: implications for excitotoxicity
- Adenosine A 2B receptor-mediated leukemia inhibitory factor release from astrocytes protects cortical neurons against excitotoxicity
- HIF‐1α triggers long‐lasting glutamate excitotoxicity via system xc− in cerebral ischaemia–reperfusion
- Green tea polyphenols attenuated glutamate excitotoxicity via antioxidative and antiapoptotic pathway in the primary cultured cortical neurons
- A new generation fatty acid amide hydrolase inhibitor protects against kainate-induced excitotoxicity
- Development of a neuroprotective peptide that preserves survival pathways by preventing Kidins220/ARMS calpain processing induced by excitotoxicity
- Bis (propyl)-cognitin protects against glutamate-induced neuro-excitotoxicity via concurrent regulation of NO, MAPK/ERK and PI3-K/Akt/GSK3β pathways
- NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotoxicity in experimental stroke
- SIRT1-mediated deacetylation of PGC1α attributes to the protection of curcumin against glutamate excitotoxicity in cortical neurons
- Transient mitochondrial permeability transition mediates excitotoxicity in glutamate-sensitive NSC34D motor neuron-like cells
- ACh receptors link two signaling pathways to neuroprotection against glutamate‐induced excitotoxicity in isolated RGCs
- Pharmacologic modulation of cerebral metabolic derangement and excitotoxicity in a porcine model of traumatic brain injury and hemorrhagic shock
- Acetate mediates alcohol excitotoxicity in dopaminergic-like PC12 cells
- Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms
- Dietary taurine supplementation ameliorates diabetic retinopathy via anti-excitotoxicity of glutamate in streptozotocin-induced Sprague-Dawley rats
- Schizandrin protects primary cultures of rat cortical cells from glutamate-induced excitotoxicity
- Acidosis-induced dysfunction of cortical GABAergic neurons through astrocyte-related excitotoxicity
- Glutamate excitotoxicity mediates neuronal apoptosis after hypothermic circulatory arrest
- Tumour associated epilepsy and glutamate excitotoxicity in patients with gliomas
- Notch signaling in response to excitotoxicity induces neurodegeneration via erroneous cell cycle reentry
- Neuroprotective effects of the mood stabilizer lamotrigine against glutamate excitotoxicity: roles of chromatin remodelling and Bcl-2 induction
- PFOS-induced excitotoxicity is dependent on Ca2+ influx via NMDA receptors in rat cerebellar granule neurons
- Adiponectin protects against glutamate-induced excitotoxicity via activating SIRT1-dependent PGC-1 expression in HT22 hippocampal neurons
- Protective Effect of Gabapentin on N-Methyl-D-aspartate–Induced excitotoxicity in Rat Hippocampal CA1 Neurons
- … -rich protamine peptides, poly-arginine peptides (R12-cyclic, R22) and arginine–tryptophan-containing peptides following in vitro excitotoxicity and/or permanent …
- Role of the c‐Jun N‐terminal kinase pathway in retinal excitotoxicity, and neuroprotection by its inhibition
- Medicinal species as MTDLs: Turnera diffusa Willd. Ex Schult inhibits CNS enzymes and delays glutamate excitotoxicity in SH-SY5Y cells via oxidative damage
- Aβ induces excitotoxicity mediated by APC/C-Cdh1 depletion that can be prevented by glutaminase inhibition promoting neuronal survival
- Glutamate excitotoxicity activates the MAPK/ERK signaling pathway and induces the survival of rat hippocampal neurons in vivo
- CX3CL1 protects neurons against excitotoxicity enhancing GLT-1 activity on astrocytes
- Oxidative stress and glutamate excitotoxicity contribute to apoptosis in cerebral venous sinus thrombosis
- Interaction between neuropeptide Y (NPY) and brain‐derived neurotrophic factor in NPY‐mediated neuroprotection against excitotoxicity: a role for microglia
- Icariin, a major constituent from Epimedium brevicornum, attenuates ibotenic acid-induced excitotoxicity in rat hippocampus
- excitotoxicity upregulates SARM1 protein expression and promotes Wallerian-like degeneration of retinal ganglion cells and their axons
- BMP4 is a peripherally-derived factor for motor neurons and attenuates glutamate-induced excitotoxicity in vitro
- Parkin overexpression protects retinal ganglion cells against glutamate excitotoxicity
- Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity
- … ischemia and reperfusion injury in middle cerebral artery occlusion of rat via modulation of apoptosis, inflammation, oxidative stress, and excitotoxicity
- Tetramethylpyrazine nitrone protects retinal ganglion cells against N‐methyl‐d‐aspartate‐induced excitotoxicity
- Mesenchymal stem cell protection of neurons against glutamate excitotoxicity involves reduction of NMDA-triggered calcium responses and surface GluR1, and is …
- RNF146 inhibits excessive autophagy by modulating the Wnt-β-Catenin pathway in glutamate excitotoxicity injury
- A novel tetramethylpyrazine derivative prophylactically protects against glutamate-induced excitotoxicity in primary neurons through the blockage of N-methyl …
- αCaMKII is differentially regulated in brain regions that exhibit differing sensitivities to ischemia and excitotoxicity
- Cannabinoid receptor activation reduces TNFα-induced surface localization of AMPAR-type glutamate receptors and excitotoxicity
- Real‐time visualization of cytoplasmic calpain activation and calcium deregulation in acute glutamate excitotoxicity
- Astrocyte-dependent vulnerability to excitotoxicity in spermine oxidase-overexpressing mouse
- excitotoxicity and mitochondrial dysfunction underlie age-dependent ischemic white matter injury
- Mitochondrial fragmentation in excitotoxicity requires ROCK activation
- Protection of neuronal cells from excitotoxicity by disrupting nNOS-PSD95 interaction with a small molecule SCR-4026
- Melanopsin-expressing retinal ganglion cells are relatively resistant to excitotoxicity induced by N-methyl-d-aspartate
- Ghrelin protects spinal cord motoneurons against chronic glutamate excitotoxicity by inhibiting microglial activation
- Depletion of polysialic acid from neural cell adhesion molecule (PSA-NCAM) increases CA3 dendritic arborization and increases vulnerability to excitotoxicity
- Neuroprotection against glutamate-induced excitotoxicity and induction of neurite outgrowth by T-006, a novel multifunctional derivative of tetramethylpyrazine in …
- Changes in cholesterol biosynthetic and transport pathways after excitotoxicity
- Both prolactin (PRL) and a molecular mimic of phosphorylated PRL, S179D-PRL, protect the hippocampus of female rats against excitotoxicity
- Blocking glutamate carboxypeptidase II inhibits glutamate excitotoxicity and regulates immune responses in experimental autoimmune encephalomyelitis
- Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: a novel pharmacological strategy against brain injury
- Knockdown of the aryl hydrocarbon receptor attenuates excitotoxicity and enhances NMDA‐induced BDNF expression in cortical neurons
- Selective mGluR1 antagonist EMQMCM inhibits the kainate-induced excitotoxicity in primary neuronal cultures and in the rat hippocampus
- Acute treatment with red wine polyphenols protects from ischemia-induced excitotoxicity, energy failure and oxidative stress in rats
- Identification of Bax-interacting proteins in oligodendrocyte progenitors during glutamate excitotoxicity and perinatal hypoxia–ischemia
- Knockdown of m‐calpain increases survival of primary hippocampal neurons following NMDA excitotoxicity
- Striatal glutamate induces retrograde excitotoxicity and neuronal degeneration of intralaminar thalamic nuclei: their potential relevance for P arkinson’s disease
- Neuroprotective effects of oxymatrine against excitotoxicity partially through down-regulation of NR2B-containing NMDA receptors
- Self‐induced accumulation of glutamate in striatal astrocytes and basal ganglia excitotoxicity
- Ciliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake
- Unconjugated TAT carrier peptide protects against excitotoxicity
- O-GlcNAc glycosylation of nNOS promotes neuronal apoptosis following glutamate excitotoxicity
- Neuroprotective effects of intrastriatal injection of rapamycin in a mouse model of excitotoxicity induced by quinolinic acid
- Activation of ERK1/2 and PI3K/Akt by IGF-1 on GAP-43 expression in DRG neurons with excitotoxicity induced by glutamate in vitro
- Sodium metabisulfite: effects on ionic currents and excitotoxicity
- Nicotine‐mediated neuroprotection of rat spinal networks against excitotoxicity
- excitotoxicity‐induced endocytosis confers drug targeting in cerebral ischemia
- Spatiotemporal resolution of BDNF neuroprotection against glutamate excitotoxicity in cultured hippocampal neurons