Cianidanol

Cianidanol (Ci), also known as (+)-catechin, is a flavonoid, a type of plant-based compound with antioxidant properties. It is a natural polyphenolic compound found in various plants, including tea, cocoa, grapes, and fruits. Catechin is a member of the flavan-3-ol class of flavonoids, and it has been widely studied for its potential health benefits, including anti-inflammatory, anti-cancer, and anti-diabetic properties. It has also been found to improve cardiovascular health by reducing the risk of coronary heart disease, reducing blood pressure, and improving cholesterol levels. Furthermore, catechin has been shown to have neuroprotective effects and may help prevent cognitive decline and dementia. Overall, cianidanol (Ci) or catechin is a potent natural compound with various potential health benefits, and its consumption through a healthy diet or supplementation may help promote overall wellness.

Antioxidant properties of Cianidanol:

Cianidanol has strong antioxidant properties that may help protect the body against damage from free radicals, which are unstable molecules that can cause cellular damage and contribute to the development of chronic diseases like cancer, diabetes, and heart disease.

Cianidanol for Cardiovascular Health:

Studies have suggested that cianidanol may help improve cardiovascular health by promoting healthy blood pressure levels and reducing the risk of blood clots. It may also help improve blood vessel function and reduce inflammation, both of which can contribute to the development of cardiovascular disease.

Cianidanol for Neuroprotective Effects:

Some research has suggested that cianidanol may have neuroprotective effects, meaning it may help protect the brain against damage and reduce the risk of neurological disorders like Alzheimer’s disease and Parkinson’s disease. Cianidanol may do this by reducing inflammation and oxidative stress in the brain, as well as by promoting healthy blood flow and protecting brain cells from damage.

Additional Studies

1. Cianidanol therapy for HBe‐antigen‐positive chronic hepatitis: a multicentre, double‐blind study
2. Development and evaluation of the essential oil from Magnolia fargesii for enhancing the transdermal absorption of theophylline and cianidanol
3. cianidanol and its metabolites bind tightly to red cells and are responsible for the production of auto‐and/or drug‐dependent antibodies against these cells
4. Effect of cianidanol on natural killer cell activity in patients with chronic B virus hepatitis.
5. Effects of cianidanol on the blood lipid peroxide status in patients with chronic hepatitis.
6. The effect of cianidanol on rat hepatic monooxygenase activities.
7. Molecular docking analysis of cianidanol fromGinkgo biloba with HER2+ breast cancer target
8. Photo-stability of several crystal forms of cianidanol
9. Influence of cianidanol on specific and non-specific immune mechanisms.
10. cianidanol ([+]-cyanidanol-3) prevents the development of abdominal adhesions in rats
11. Synthesis of (3-2H)-and (3-3H)-cianidanol
12. Photo-stability of cianidanol in aqueous solution and in the solid state
13. The pathogenesis of cianidanol-induced fever
14. Effect of cianidanol on chronic liver injury induced by carbon tetrachloride and on liver regeneration after partial hepatectomy in rats
15. Effects of cianidanol (KB-53) on liver cirrhosis induced by CCl4 in rats: a pathological investigation
16. Immunomodulating properties of cianidanol on responsiveness and function of human peripheral blood T-cells and K-cells
17. The immunoenhancing effect of cianidanol (C) on macrophages and on the T-cell system.
18. Effects of cianidanol (KB-53) on experimental liver injury in mice–histopathological, histochemical and enzyme-histochemical studies
19. Effect of cianidanol (KB-53) on the activity of mouse cytotoxic-T-lymphocytes
20. Effect of cianidanol (KB-53) on the activity of mouse natural killer cells
21. Crystal forms of cianidanol
22. Effect of cianidanol (KB-53) on delayed skin reactions in mice compromised by carbon tetrachloride and 1-naphthylisothiocyanate
23. Augmentation of immune responses in vitro by cianidanol
24. Protection of liver cells from experimentally-induced liver cell injury by cianidanol, a constituent of Uncaria Ganbir
25. Investigation of cianidanol metabolism using capillary GC/MS