April 30, 2019

AUTOPHAGY: 1,000 Scientific Studies

Autophagy (or autophagocytosis) (from the Ancient Greek αὐτόφαγος autóphagos, meaning “self-devouring”[1] and κύτος kýtos, meaning “hollow”[2]) is the natural, regulated mechanism of the cell that removes unnecessary or dysfunctional components.[3] It allows the orderly degradation […]
May 1, 2019

AMPK

AMP-activated protein kinase (AMPK) is a cellular energy regulator that plays a critical role in maintaining metabolic balance. In obesity, AMPK activity is often impaired, hindering […]
July 17, 2019

SIRT1

The anti-aging effects of SIRT1 activation include: – Protection against oxidative stress – Regulation of age-related diseases – Increased stress resistance – Potential lifespan elongation – […]
July 27, 2019

FOXO3

FOXO3 belongs to the O subclass of the forkhead family of transcription factorswhich are characterized by a distinct fork head DNA-binding domain. There are three other […]
July 28, 2019

FGF21

Fibroblast growth factor 21 (FGF21) is a hormone-like member of FGF family which controls metabolic multiorgan crosstalk enhancing energy expenditure through glucose and lipid metabolism. In […]
July 30, 2019

KLOTHO

Klotho is a transmembrane protein that, in addition to other effects, provides some control over the sensitivity of the organism to insulin and appears to be […]
January 4, 2020

P53

P53 is a crucial tumor suppressor protein that acts as the body’s guardian of the genome. When DNA damage occurs from environmental stresses like radiation or […]
January 6, 2020

HSP90

Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation. It also stabilizes a number of proteins […]